> Dihydrolipoamide branched chain transacylase E2 (DBT)
NCBI UniGene banner graphic
PubMed Nucleotide Protein Genome Structure Popset Taxonomy
 Search
NCBI

UniGene
Homepage
FAQs
Help
Query Tips
Build Info
Library Browser
DDD
Download UniGene

Related Databases
Gene
HomoloGene
EST
SRA

NIH cDNA Projects
MGC | ZGC | XGC
Finding cDNAs
UGID:3321394     UniGene Hs.709187     Homo sapiens (human)   DBT Order cDNA clone, Links
Dihydrolipoamide branched chain transacylase E2 (DBT)

Human protein-coding gene DBT. Represented by 163 ESTs from 118 cDNA libraries. Corresponds to reference sequence NM_001918.3. [UniGene 3321394 - Hs.709187]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001909.3 DBT gene product H. sapiens 100.0 481
NP_034152.2 Dbt gene product M. musculus 93.2 481
NP_001087792.1 dihydrolipoamide branched chain transacylase E2 X. laevis 82.9 491
NP_001013533.1 dbt gene product D. rerio 77.9 492
NP_495670.1 Protein ZK669.4 C. elegans 59.0 418
NP_573000.1 CG5599 D. melanogaster 53.6 433
NP_187341.1 2-oxoisovalerate dehydrogenase E2 component (dihydrolipoyl transacylase) A. thaliana 51.9 232
XP_965477.1 hypothetical protein NCU02704 N. crassa 46.8 186
Other hits (2 of 51) [Show all]SpeciesId(%)Len(aa)
XP_001107312.1 PREDICTED: lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial isoform 3 M. mulatta 99.2 481
XP_003892313.1 PREDICTED: lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial P. anubis 99.2 481

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; blood; embryonic tissue; pituitary gland; kidney; testis; uncharacterized tissue; mixed; pharynx; thyroid; prostate; pancreas; placenta; lung; skin; umbilical cord; uterus; intestine; bladder; bone marrow; mammary gland; larynx; mouth; heart; liver; eye; connective tissue; esophagus; spleen; trachea; thymus; cervix; stomach; lymph; lymph node; adipose tissue; bone
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 1
Map position: 1p31
UniSTS entry: Dbt
UniSTS entry: Chr 1 SHGC-35260 [Map Viewer]
UniSTS entry: Chr 1 RH39750
UniSTS entry: Chr 1 SHGC-75206 [Map Viewer]
UniSTS entry: Chr 1 L17971
UniSTS entry: Chr 1 L18441
UniSTS entry: Chr 1 D1S1423
UniSTS entry: Chr 1 D11S2921
UniSTS entry: Chr 1 D1S1361
UniSTS entry: Chr 1 L17709
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (11)

BT007372.1 Homo sapiens dihydrolipoamide branched chain transacylase (E2 component of branched chain keto acid dehydrogenase complex; maple syrup urine disease) mRNA, complete cds P
NM_001918.3 Homo sapiens dihydrolipoamide branched chain transacylase E2 (DBT), nuclear gene encoding mitochondrial protein, mRNA PA
AK024946.1 Homo sapiens cDNA: FLJ21293 fis, clone COL01972 A
M19301.1 Human branched-chain alpha-keto acid dehydrogenase (E2) mRNA, complete cds P
M27093.1 Homo sapiens nuclear-encoded mitochondrial branched chain alpha-keto acid dehydrogenase transacylase subunit (E2b) mRNA, complete cds P
BC016675.1 Homo sapiens dihydrolipoamide branched chain transacylase E2, mRNA (cDNA clone MGC:9061 IMAGE:3924492), complete cds PA
AK313191.1 Homo sapiens cDNA, FLJ93690, Homo sapiens dihydrolipoamide branched chain transacylase (E2component of branched chain keto acid dehydrogenase complex; maplesyrup urine disease) (DBT), mRNA P
X66785.1 H.sapiens mRNA for transacylase (DBT) P
BC030002.1 Homo sapiens dihydrolipoamide branched chain transacylase E2, mRNA (cDNA clone IMAGE:3924372) PA
X57677.1 H.sapiens mRNA for transacylase, partial
J03208.1 Human branched chain acyltransferase mRNA, complete cds P

EST sequences (10 of 163) [Show all sequences]

AI004719.1 Clone IMAGE:1624563 embryonic tissue 3' read PA
R23046.1 Clone IMAGE:131003 placenta 5' read
AI139973.1 Clone IMAGE:1689886 mixed 3' read
BX097005.1 Clone IMAGp998B06134_;_IMAGE:128933 mixed A
BX108752.1 Clone IMAGp998H12181_;_IMAGE:131003 placenta P
BX108381.1 Clone IMAGp998C09153_;_IMAGE:32095 brain A
R27465.1 Clone IMAGE:133472 placenta 3' read
CB116378.1 Clone L10ChoCK0-5-G12 liver 5' read
AI367373.1 Clone IMAGE:1989345 uterus 3' read A
AI420361.1 Clone IMAGE:2094251 prostate 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
NLM | NIH | UniGene | Privacy Statement | Disclaimer | NCBI Help