Insulin induced gene 2 (INSIG2)

NCBI

UniGene
Homepage
FAQs
Help
Query Tips
Build Info
Library Browser
DDD
Download UniGene

Related Databases
Gene
HomoloGene
EST
SRA

NIH cDNA Projects
MGC | ZGC | XGC
Finding cDNAs

UGID:132027 UniGene Hs.7089 Homo sapiens (human) INSIG2

Order cDNA clone, Links

Insulin induced gene 2 (INSIG2)

Human protein-coding gene INSIG2. Represented by 239 ESTs from 122 cDNA libraries. Corresponds to reference sequence NM_016133.2. [UniGene 132027 - Hs.7089]

SELECTED PROTEIN SIMILARITIES

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.

Best Hits and Hits from model organisms		Species	Id(%)	Len(aa)
XP_002799450.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: insulin-induced gene 2 protein-like isoform 1	M. mulatta	100.0	224
NP_001162382.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	INSIG2 gene product	P. anubis	100.0	224
XP_001155360.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: insulin-induced gene 2 protein isoform 3	P. troglodytes	100.0	224
NP_057217.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	INSIG2 gene product	H. sapiens	100.0	224
XP_003581891.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: insulin-induced gene 2 protein isoform 1	B. taurus	100.0	224
XP_002712431.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: insulin induced gene 2-like	O. cuniculus	100.0	224
XP_001488133.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: insulin-induced gene 2 protein-like	E. caballus	99.6	224
NP_001123440.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	INSIG2 gene product	S. scrofa	99.6	224
XP_004004796.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: insulin-induced gene 2 protein	O. aries	99.6	224
NP_598509.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Insig2 gene product	M. musculus	98.2	224
NP_001087688.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	insulin-induced gene 2 protein	X. laevis	89.3	204
NP_997969.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	insig2 gene product	D. rerio	87.2	210
Other hits (2 of 18) [Show all]		Species	Id(%)	Len(aa)
XP_853105.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: insulin-induced gene 2 protein	C. lupus familiaris	99.1	224
NP_835192.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Insig2 gene product	R. norvegicus	98.2	224

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

	EST Profile:	Approximate expression patterns inferred from EST sources. [Show more entries with profiles like this]
	GEO Profiles:	Experimental gene expression data (Gene Expression Omnibus).
	cDNA Sources:	brain; pharynx; testis; mixed; bladder; embryonic tissue; placenta; kidney; lung; uncharacterized tissue; muscle; pancreas; uterus; lymph node; intestine; parathyroid; eye; trachea; pituitary gland; skin; stomach; ascites; connective tissue; thymus; bone; liver; mammary gland; vascular; prostate; nerve; blood

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	2
Map position:	2q14.2
UniSTS entry:	Chr 2	STS-AA009428
UniSTS entry:	Chr 2	RH103254
UniSTS entry:	Chr 2	WI-15665	[Map Viewer]
UniSTS entry:	Chr 2	RH11985

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (9)

AL080184.1	Homo sapiens mRNA; cDNA DKFZp434O071 (from clone DKFZp434O071)	A
BX647805.1	Homo sapiens mRNA; cDNA DKFZp781K1743 (from clone DKFZp781K1743)	PA
AF125392.1	Homo sapiens insulin induced protein 2 mRNA, complete cds	P
AK021692.1	Homo sapiens cDNA FLJ11630 fis, clone HEMBA1004248, moderately similar to INSULIN-INDUCED GROWTH RESPONSE PROTEIN CL-6	P
BC022475.1	Homo sapiens insulin induced gene 2, mRNA (cDNA clone MGC:26273 IMAGE:4794938), complete cds	PA
AK291433.1	Homo sapiens cDNA FLJ76618 complete cds, highly similar to Homo sapiens insulin induced gene 2 (INSIG2), mRNA	P
AK298599.1	Homo sapiens cDNA FLJ51633 complete cds, highly similar to Homo sapiens insulin induced gene 2 (INSIG2), mRNA	P
AF527632.1	Homo sapiens INSIG-2 membrane protein mRNA, complete cds	PA
NM_016133.2	Homo sapiens insulin induced gene 2 (INSIG2), mRNA	PA

EST sequences (10 of 239) [Show all sequences]

AA970419.1	Clone IMAGE:1573065	kidney	3' read	A
AA971573.1	Clone IMAGE:1583524	mixed	3' read
AI027128.1	Clone IMAGE:1649795	parathyroid	3' read	A
AI027886.1	Clone IMAGE:1650470	parathyroid	3' read
R19146.1	Clone IMAGE:33322	brain	5' read
AI219843.1	Clone IMAGE:1841777	mixed	3' read	A
R28035.1	Clone IMAGE:134674	placenta	5' read
R28057.1	Clone IMAGE:134697	placenta	5' read
R28257.1	Clone IMAGE:134674	placenta	3' read
R28277.1	Clone IMAGE:134697	placenta	3' read

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria