> Three prime repair exonuclease 1 (TREX1)
NCBI UniGene banner graphic
PubMed Nucleotide Protein Genome Structure Popset Taxonomy
 Search
NCBI

UniGene
Homepage
FAQs
Help
Query Tips
Build Info
Library Browser
DDD
Download UniGene

Related Databases
Gene
HomoloGene
EST
SRA

NIH cDNA Projects
MGC | ZGC | XGC
Finding cDNAs
UGID:3273221     UniGene Hs.707026     Homo sapiens (human)   TREX1 Links
Three prime repair exonuclease 1 (TREX1)

Human protein-coding gene TREX1. Represented by 105 ESTs from 71 cDNA libraries. EST representation biased toward adult. Corresponds to 3 reference sequences (different isoforms). [UniGene 3273221 - Hs.707026]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_057465.1 TREX1 gene product H. sapiens 100.0 368
NP_035767.4 Trex1 gene product M. musculus 77.4 313
Other hits (2 of 13) [Show all]SpeciesId(%)Len(aa)
XP_003309834.1 PREDICTED: three prime repair exonuclease 1 isoform 1 P. troglodytes 99.5 368
XP_003894527.1 PREDICTED: three prime repair exonuclease 1 P. anubis 97.4 303

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: adult [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: mixed; brain; uncharacterized tissue; prostate; lymph node; lung; kidney; placenta; intestine; blood; pancreas; testis; mammary gland; tonsil; eye; bone marrow; cervix; skin; connective tissue; uterus; lymph; ovary; ascites; salivary gland; ganglia; spleen; pineal gland; larynx
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 3
Map position: 3p21.31
UniSTS entry: Chr 3 WI-11814 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (9)

AJ243797.1 Homo sapiens mRNA for deoxyribonuclease III (drn3 gene) PA
AL137745.1 Homo sapiens mRNA; cDNA DKFZp434J0310 (from clone DKFZp434J0310) PA
CR457119.1 Homo sapiens full open reading frame cDNA clone RZPDo834B0212D for gene TREX1, three prime repair exonuclease 1; complete cds, incl. stopcodon P
NM_016381.4 Homo sapiens three prime repair exonuclease 1 (TREX1), transcript variant 1, mRNA PA
BT020053.1 Homo sapiens three prime repair exonuclease 1 mRNA, complete cds P
BT020052.1 Homo sapiens three prime repair exonuclease 1 mRNA, complete cds P
AF151105.3 Homo sapiens 3'-5' exonuclease TREX1 mRNA, complete cds PA
NM_033629.3 Homo sapiens three prime repair exonuclease 1 (TREX1), transcript variant 4, mRNA PA
NM_007248.2 Homo sapiens three prime repair exonuclease 1 (TREX1), transcript variant 5, mRNA PA

EST sequences (10 of 105) [Show all sequences]

AI091422.1 Clone IMAGE:1651428 mixed 3' read PA
R23917.1 Clone IMAGE:131083 placenta 5' read
R23918.1 Clone IMAGE:131083 placenta 3' read A
AI285342.1 Clone IMAGE:1874637 intestine 3' read PA
AI300592.1 Clone IMAGE:1902247 kidney 3' read PA
AI422509.1 Clone IMAGE:2095916 brain 3' read A
AI453560.1 Clone IMAGE:2145613 mixed 3' read PA
AI472848.1 Clone IMAGE:2147251 mixed 3' read PA
AI472938.1 Clone IMAGE:2147294 mixed 3' read PA
AI479115.1 Clone IMAGE:2158195 uncharacterized tissue 3' read PA


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
NLM | NIH | UniGene | Privacy Statement | Disclaimer | NCBI Help