> Siah E3 ubiquitin protein ligase 1 (SIAH1)
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UGID:3273023     UniGene Hs.706828     Homo sapiens (human)   SIAH1 Order cDNA clone, Links
Siah E3 ubiquitin protein ligase 1 (SIAH1)

Human protein-coding gene SIAH1. Represented by 338 ESTs from 160 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 3273023 - Hs.706828]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001114300.1 PREDICTED: e3 ubiquitin-protein ligase SIAH1 isoform 1 M. mulatta 100.0 312
XP_003916898.1 PREDICTED: E3 ubiquitin-protein ligase SIAH1 P. anubis 100.0 312
NP_001006611.1 SIAH1 gene product H. sapiens 100.0 312
NP_033198.1 Siah1a gene product M. musculus 100.0 281
NP_543181.2 Siah1a gene product R. norvegicus 100.0 281
NP_001085438.1 siah E3 ubiquitin protein ligase 1 X. laevis 100.0 281
NP_001015836.1 siah1 gene product X. tropicalis 100.0 281
XP_414105.2 PREDICTED: E3 ubiquitin-protein ligase SIAH1 G. gallus 100.0 281
XP_003209815.1 PREDICTED: e3 ubiquitin-protein ligase SIAH1-like M. gallopavo 100.0 281
XP_003428562.1 PREDICTED: E3 ubiquitin-protein ligase SIAH1-like O. anatinus 100.0 281
NP_001233288.1 SIAH1 gene product P. troglodytes 100.0 281
XP_001490900.2 PREDICTED: e3 ubiquitin-protein ligase SIAH1-like E. caballus 100.0 281
XP_003127039.1 PREDICTED: E3 ubiquitin-protein ligase SIAH1-like isoform 1 S. scrofa 100.0 281
XP_004015022.1 PREDICTED: E3 ubiquitin-protein ligase SIAH1 O. aries 100.0 281
XP_001370323.1 PREDICTED: e3 ubiquitin-protein ligase SIAH1 M. domestica 99.7 312
XP_003222961.1 PREDICTED: e3 ubiquitin-protein ligase SIAH1-like A. carolinensis 99.7 312
XP_003638979.1 PREDICTED: E3 ubiquitin-protein ligase SIAH1-like C. lupus familiaris 99.7 312
NP_001180122.1 SIAH1 gene product B. taurus 99.7 312
XP_002721389.1 PREDICTED: seven in absentia homolog 1 O. cuniculus 99.7 312
NP_955815.1 siah1 gene product D. rerio 98.9 283
NP_476725.1 seven in absentia, isoform A D. melanogaster 85.2 304
NP_500409.1 Protein SIAH-1 C. elegans 72.6 325
Other hits (2 of 21) [Show all]SpeciesId(%)Len(aa)
XP_002197771.1 PREDICTED: E3 ubiquitin-protein ligase SIAH1 T. guttata 99.4 312
XP_004069806.1 PREDICTED: E3 ubiquitin-protein ligase Siah1-like O. latipes 98.9 283

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: placenta; mixed; brain; testis; uncharacterized tissue; kidney; lung; intestine; embryonic tissue; ovary; bladder; stomach; salivary gland; ear; mammary gland; thyroid; mouth; esophagus; spleen; bone marrow; skin; prostate; lymph node; eye; liver; pancreas; uterus; heart; cervix; trachea; epididymis; larynx; blood; thymus; connective tissue; muscle; vascular; bone; pineal gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 16
Map position: 16q12
UniSTS entry: Chr 16 G20682
UniSTS entry: Chr 16 RH17142
UniSTS entry: Chr 16 RH68358
UniSTS entry: Chr 16 RH68065
UniSTS entry: Chr 16 RH64986
UniSTS entry: Chr 16 PMC149152P1
UniSTS entry: Chr 16 RH75389
UniSTS entry: Chr 16 SIAH1_2345
UniSTS entry: Chr 1 D1S1425
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (16)

BC042550.1 Homo sapiens seven in absentia homolog 1 (Drosophila), mRNA (cDNA clone MGC:34550 IMAGE:5198176), complete cds PA
BX647064.1 Homo sapiens mRNA; cDNA DKFZp686L1897 (from clone DKFZp686L1897); complete cds PA
NM_003031.3 Homo sapiens siah E3 ubiquitin protein ligase 1 (SIAH1), transcript variant 1, mRNA P
NM_001006610.1 Homo sapiens siah E3 ubiquitin protein ligase 1 (SIAH1), transcript variant 2, mRNA PA
BC044920.1 Homo sapiens seven in absentia homolog 1 (Drosophila), mRNA (cDNA clone MGC:44340 IMAGE:5295925), complete cds PA
AK023458.1 Homo sapiens cDNA FLJ13396 fis, clone PLACE1001323
AK225895.1 Homo sapiens mRNA for seven in absentia homolog 1 isoform a variant, clone: FCC120G04 P
EF026094.1 Homo sapiens SIAH1 short protein (SIAH1) mRNA, complete cds, alternatively spliced P
AK313861.1 Homo sapiens cDNA, FLJ94493, highly similar to Homo sapiens seven in absentia homolog 1 (Drosophila) (SIAH1),mRNA P
AK094663.1 Homo sapiens cDNA FLJ37344 fis, clone BRAMY2021139, highly similar to Ubiquitin ligase SIAH1 (EC 6.3.2.-) P
AB451377.1 Homo sapiens SIAH1 mRNA for seven in absentia homolog 1 isoform a, partial cds, clone: FLJ08065AAAF P
AB451253.1 Homo sapiens SIAH1 mRNA for seven in absentia homolog 1 isoform a, complete cds, clone: FLJ08065AAAN P
U63295.1 Homo sapiens seven in absentia homolog mRNA, complete cds P
BC018193.1 Homo sapiens seven in absentia homolog 1 (Drosophila), mRNA (cDNA clone IMAGE:3857590), containing frame-shift errors PA
BC035562.1 Homo sapiens seven in absentia homolog 1 (Drosophila), mRNA (cDNA clone MGC:40343 IMAGE:5224755), complete cds PA
U76247.1 Human hSIAH1 mRNA, complete cds P

EST sequences (10 of 338) [Show all sequences]

AA923663.1 Clone IMAGE:1457224 intestine 3' read P
AA971734.1 Clone IMAGE:1584620 lung 3' read P
AA987413.1 Clone IMAGE:1593886 kidney 3' read P
AA996352.1 Clone IMAGE:1603742 lung 3' read P
AA904493.1 Clone IMAGE:1507213 mixed 3' read
R17298.1 Clone IMAGE:31849 brain 5' read P
AI023418.1 Clone IMAGE:1652308 mixed 3' read A
AI034173.1 Clone IMAGE:1656129 mixed 3' read
AI052673.1 Clone IMAGE:1675697 mixed 3' read A
AI076884.1 Clone IMAGE:1670277 brain 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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