> Protein phosphatase 1, catalytic subunit, beta isozyme (PPP1CB)
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UGID:3094792     UniGene Hs.702907     Homo sapiens (human)   PPP1CB Order cDNA clone, Links
Protein phosphatase 1, catalytic subunit, beta isozyme (PPP1CB)

Human protein-coding gene PPP1CB. Represented by 1206 ESTs from 430 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 3094792 - Hs.702907]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_766295.2 Ppp1cb gene product M. musculus 100.0 326
NP_037197.1 Ppp1cb gene product R. norvegicus 100.0 326
XP_003216122.1 PREDICTED: serine/threonine-protein phosphatase PP1-beta catalytic subunit-like A. carolinensis 100.0 326
NP_001187645.1 serine/threonine-protein phosphatase pp1-beta catalytic subunit I. punctatus 100.0 326
XP_004080069.1 PREDICTED: serine/threonine-protein phosphatase PP1-beta catalytic subunit-like O. latipes 100.0 326
NP_001085426.1 serine/threonine-protein phosphatase PP1-beta catalytic subunit X. laevis 100.0 326
NP_001011467.1 ppp1cb gene product X. tropicalis 100.0 326
NP_990453.1 PPP1CB gene product G. gallus 100.0 326
XP_001101844.1 PREDICTED: serine/threonine-protein phosphatase PP1-beta catalytic subunit-like isoform 2 M. mulatta 100.0 326
XP_003908502.1 PREDICTED: serine/threonine-protein phosphatase PP1-beta catalytic subunit isoform 1 P. anubis 100.0 326
XP_001161723.1 PREDICTED: serine/threonine-protein phosphatase PP1-beta catalytic subunit isoform 2 P. troglodytes 100.0 326
NP_002700.1 PPP1CB gene product H. sapiens 100.0 326
NP_999349.1 PPP1CB gene product S. scrofa 100.0 326
NP_001029825.1 PPP1CB gene product B. taurus 100.0 326
NP_001095192.1 PP1-BETA gene product O. cuniculus 100.0 326
XP_001380599.2 PREDICTED: serine/threonine-protein phosphatase PP1-beta catalytic subunit-like M. domestica 100.0 311
XP_003363061.1 PREDICTED: serine/threonine-protein phosphatase PP1-beta catalytic subunit-like isoform 2 E. caballus 100.0 298
XP_004005838.1 PREDICTED: serine/threonine-protein phosphatase PP1-beta catalytic subunit O. aries 100.0 298
XP_002613214.1 hypothetical protein BRAFLDRAFT_210558 B. floridae 99.7 327
XP_003962572.1 PREDICTED: serine/threonine-protein phosphatase PP1-beta catalytic subunit-like isoform 1 T. rubripes 99.7 326
NP_001135160.1 serine/threonine-protein phosphatase PP1-beta catalytic subunit S. salar 99.7 326
XP_003442982.1 PREDICTED: serine/threonine-protein phosphatase PP1-beta catalytic subunit-like isoform 1 O. niloticus 99.7 326
NP_001003034.1 PPP1CB gene product C. lupus familiaris 99.7 326
NP_001004527.2 ppp1cb gene product D. rerio 99.4 326
NP_524738.1 flapwing, isoform B D. melanogaster 94.8 329
NP_001022616.1 Protein GSP-2 C. elegans 94.5 329
XP_956154.2 PP1 Serine/threonine protein phosphatase N. crassa 93.1 305
NP_011059.3 Glc7p S. cerevisiae 91.3 310
XP_001701579.1 protein phosphatase 1 C. reinhardtii 89.2 296
NP_200724.1 serine/threonine-protein phosphatase PP1 isozyme 2 A. thaliana 87.1 311
Other hits (2 of 47) [Show all]SpeciesId(%)Len(aa)
XP_002731251.1 PREDICTED: protein phosphatase 1, catalytic subunit, beta-like isoform 1 S. kowalevskii 98.5 324
XP_001604472.1 PREDICTED: serine/threonine-protein phosphatase PP1-beta catalytic subunit-like isoform 1 N. vitripennis 97.9 328

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; uterus; placenta; testis; lung; intestine; uncharacterized tissue; prostate; kidney; liver; lymph node; trachea; thymus; embryonic tissue; eye; mammary gland; parathyroid; vascular; muscle; heart; skin; connective tissue; blood; spleen; mouth; amniotic fluid; mixed; esophagus; stomach; bladder; ovary; pancreas; adrenal gland; cervix; thyroid; bone marrow; bone; larynx; pituitary gland; salivary gland; ascites; lymph; ganglia; pharynx; adipose tissue; nerve
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 2
Map position: 2p23
UniSTS entry: Ppp1cb
UniSTS entry: Chr 2 STS-W67887
UniSTS entry: Chr 2 EST16D1
UniSTS entry: Ppp1cb
UniSTS entry: Chr 2 D6S1941
UniSTS entry: Chr 2 PPP1CB_3843
UniSTS entry: G43127
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (15)

BX647970.1 Homo sapiens mRNA; cDNA DKFZp686E2152 (from clone DKFZp686E2152) PA
BX647295.1 Homo sapiens mRNA; cDNA DKFZp781I1636 (from clone DKFZp781I1636) A
NM_002709.2 Homo sapiens protein phosphatase 1, catalytic subunit, beta isozyme (PPP1CB), transcript variant 1, mRNA P
NM_206876.1 Homo sapiens protein phosphatase 1, catalytic subunit, beta isozyme (PPP1CB), transcript variant 3, mRNA P
CR542285.1 Homo sapiens full open reading frame cDNA clone RZPDo834H1226D for gene PPP1CB, protein phosphatase 1, catalytic subunit, beta isoform; complete cds, without stopcodon P
CR542263.1 Homo sapiens full open reading frame cDNA clone RZPDo834D1126D for gene PPP1CB, protein phosphatase 1, catalytic subunit, beta isoform; complete cds, incl. stopcodon P
BT019744.1 Homo sapiens protein phosphatase 1, catalytic subunit, beta isoform mRNA, complete cds P
AF092905.1 Homo sapiens protein phosphatase type-1 catalytic subunit delta isoform (PPCS1D) mRNA, complete cds P
BC002697.2 Homo sapiens protein phosphatase 1, catalytic subunit, beta isoform, mRNA (cDNA clone MGC:3672 IMAGE:3609386), complete cds PA
BC012045.1 Homo sapiens protein phosphatase 1, catalytic subunit, beta isoform, mRNA (cDNA clone MGC:10563 IMAGE:3631338), complete cds PA
AK312329.1 Homo sapiens cDNA, FLJ92643, Homo sapiens protein phosphatase 1, catalytic subunit, beta isoform(PPP1CB), mRNA P
AK303682.1 Homo sapiens cDNA FLJ58972 complete cds, highly similar to Serine/threonine-protein phosphatase PP1-beta catalytic subunit (EC 3.1.3.16) PA
AK295957.1 Homo sapiens cDNA FLJ58189 complete cds, highly similar to Serine/threonine-protein phosphatase PP1-beta catalytic subunit (EC 3.1.3.16) P
AK316532.1 Homo sapiens cDNA, FLJ79431 complete cds, highly similar to Serine/threonine-protein phosphatase PP1-beta catalytic subunit (EC 3.1.3.16) P
X80910.1 H.sapiens PPP1CB mRNA P

EST sequences (10 of 1206) [Show all sequences]

R14092.1 Clone IMAGE:27519 brain 5' read
R15121.1 Clone IMAGE:29625 brain 5' read
AA989083.1 Clone IMAGE:1602937 lung 3' read
AA909637.1 Clone IMAGE:1522987 mixed 3' read P
AI002043.1 Clone IMAGE:1637814 mammary gland 3' read
R17810.1 Clone IMAGE:31865 brain 5' read
AI038401.1 Clone IMAGE:1657015 mixed 3' read
AI039807.1 Clone IMAGE:1659668 embryonic tissue 3' read
AI050966.1 Clone IMAGE:1648715 parathyroid 3' read A
AI089371.1 Clone IMAGE:1695778 uterus 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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