> Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) (DAB2)
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UGID:2977236     UniGene Hs.696631     Homo sapiens (human)   DAB2 Order cDNA clone, Links
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) (DAB2)

Human protein-coding gene DAB2. Represented by 859 ESTs from 288 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 2977236 - Hs.696631]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001334.2 DAB2 gene product H. sapiens 100.0 769
XP_517792.3 PREDICTED: disabled homolog 2 isoform 2 P. troglodytes 99.9 805
NP_075607.2 Dab2 gene product M. musculus 90.9 765
NP_001083254.1 uncharacterized protein LOC398828 X. laevis 74.8 555
NP_991320.1 dab2 gene product D. rerio 73.7 361
Other hits (2 of 23) [Show all]SpeciesId(%)Len(aa)
XP_003899653.1 PREDICTED: disabled homolog 2 P. anubis 99.0 712
XP_001084792.2 PREDICTED: disabled homolog 2 M. mulatta 98.8 802

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: placenta; brain; skin; kidney; connective tissue; lung; uncharacterized tissue; liver; mixed; embryonic tissue; spleen; cervix; salivary gland; mammary gland; testis; ovary; thyroid; mouth; heart; uterus; bone; pancreas; eye; vascular; ear; muscle; adrenal gland; intestine; stomach; blood; prostate; thymus; esophagus; trachea; epididymis; larynx; bone marrow; parathyroid; ascites; nerve; umbilical cord; adipose tissue; lymph node
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 5
Map position: 5p13
UniSTS entry: Chr 5 SGC34152 [Map Viewer]
UniSTS entry: Chr 5 RH103057
UniSTS entry: Chr 5 RH67769 [Map Viewer]
UniSTS entry: Chr 5 G54013
UniSTS entry: Chr 5 DAB2
UniSTS entry: Chr 5 SGC34180 [Map Viewer]
UniSTS entry: Chr 5 RH122297
UniSTS entry: Chr 5 WI-18094 [Map Viewer]
UniSTS entry: Chr 5 SHGC-52617
UniSTS entry: MARC_11535-11536:1001596571:1
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (13)

AK130136.1 Homo sapiens cDNA FLJ26626 fis, clone MPC03831 P
AK123803.1 Homo sapiens cDNA FLJ41809 fis, clone NOVAR2001844
NM_001343.3 Homo sapiens disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) (DAB2), transcript variant 1, mRNA PA
AF188298.1 Homo sapiens disabled 2 p93 (DAB2) mRNA, alternatively spliced, complete cds PA
AK024965.1 Homo sapiens cDNA: FLJ21312 fis, clone COL02175 A
U39050.1 Human mitogen-responsive phosphoprotein (DOC-2) mRNA, complete cds P
BC003064.2 Homo sapiens disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila), mRNA (cDNA clone MGC:1764 IMAGE:3504380), complete cds PA
U53446.1 Human mitogen-responsive phosphoprotein DOC-2 mRNA, complete cds PA
AK314381.1 Homo sapiens cDNA, FLJ95154, highly similar to Homo sapiens disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) (DAB2), mRNA P
AK092836.1 Homo sapiens cDNA FLJ35517 fis, clone SPLEN2000698
AK297984.1 Homo sapiens cDNA FLJ53147 complete cds, highly similar to Disabled homolog 2 P
L16886.1 Human differentially expressed protein mRNA, partial cds P
NM_001244871.1 Homo sapiens disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) (DAB2), transcript variant 2, mRNA PA

EST sequences (10 of 859) [Show all sequences]

AA978370.1 Clone IMAGE:1588809 kidney 3' read A
AA907401.1 Clone IMAGE:1521748 lung 3' read A
AI015757.1 Clone IMAGE:1622589 embryonic tissue 3' read
AI028511.1 Clone IMAGE:1649641 parathyroid 3' read
AI039217.1 Clone IMAGE:1658034 embryonic tissue 3' read
AI051579.1 Clone IMAGE:1673781 mixed 3' read A
AI056712.1 Clone IMAGE:1669567 brain 3' read A
AI088237.1 Clone IMAGE:1693589 heart 3' read A
AI126028.1 Clone IMAGE:1713075 uterus 3' read A
AI126988.1 Clone IMAGE:1707961 heart 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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