Myosin, heavy chain 1, skeletal muscle, adult (MYH1)

Restricted Expression:

adult [show more like this]

EST Profile:

Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]

GEO Profiles:

Experimental gene expression data (Gene Expression Omnibus).

cDNA Sources:

muscle; larynx; heart; uncharacterized tissue; thyroid; liver; spinal cord; pharynx; testis; spleen; mouth; bone

NCBI

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UGID:2758937 UniGene Hs.689619 Homo sapiens (human) MYH1

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Myosin, heavy chain 1, skeletal muscle, adult (MYH1)

Human protein-coding gene MYH1. Represented by 201 ESTs from 30 cDNA libraries. EST representation biased toward adult. Corresponds to reference sequence NM_005963.3. [UniGene 2758937 - Hs.689619]

SELECTED PROTEIN SIMILARITIES

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.

Best Hits and Hits from model organisms		Species	Id(%)	Len(aa)
NP_005954.3 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	MYH1 gene product	H. sapiens	100.0	1938
XP_003953177.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: LOW QUALITY PROTEIN: myosin-1	P. troglodytes	99.9	1938
NP_109604.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Myh1 gene product	M. musculus	97.4	1941
XP_002667379.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: myosin heavy chain, fast skeletal muscle	D. rerio	85.0	1924
NP_001085070.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	myosin, heavy chain 6, cardiac muscle, alpha	X. laevis	81.8	1925
NP_001246051.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	myosin heavy chain, isoform U	D. melanogaster	60.2	1913
XP_964712.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	hypothetical protein NCU00551	N. crassa	59.3	231
NP_493596.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Protein UNC-54	C. elegans	53.5	1924
NP_011888.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	myosin 1	S. cerevisiae	49.0	157
Other hits (2 of 47) [Show all]		Species	Id(%)	Len(aa)
XP_003912394.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: myosin-1	P. anubis	98.9	1937
NP_001098421.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	MYH1 gene product	S. scrofa	97.8	1938

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	17
Map position:	17p13.1
UniSTS entry:		RH65760
UniSTS entry:	Chr 17	D17S1493E
UniSTS entry:	Chr 17	D17S1497E
UniSTS entry:	Chr 1	RH36158

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (6)

NM_005963.3	Homo sapiens myosin, heavy chain 1, skeletal muscle, adult (MYH1), mRNA	PA
AF111785.1	Homo sapiens myosin heavy chain IIx/d mRNA, complete cds	P
BC114545.1	Homo sapiens myosin, heavy chain 1, skeletal muscle, adult, mRNA (cDNA clone MGC:133384 IMAGE:40070022), complete cds	P
AK310004.1	Homo sapiens cDNA, FLJ17046	PA
BC022376.2	Homo sapiens myosin, heavy chain 1, skeletal muscle, adult, mRNA (cDNA clone IMAGE:4338358), partial cds	PA
X03740.1	Human skeletal mRNA for myosin heavy chain light meromyosin region	P

EST sequences (10 of 201) [Show all sequences]

F24083.1	Clone s4000002C01	muscle	P
F24623.1	Clone s4000016E06	muscle	A
F24750.1	Clone s4000018F12	muscle
F25925.1	Clone s4000045G04	muscle	P
F26883.1	Clone s4000061G02	muscle
F26983.1	Clone s4000063D08	muscle	P
F27373.1	Clone s4000069F02	muscle
F28024.1	Clone s4000031B03	muscle
F28528.1	Clone s3000018C04	muscle
F29228.1	Clone s4000074A09	muscle	P

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria