> Toll-like receptor 8 (TLR8)
NCBI UniGene banner graphic
PubMed Nucleotide Protein Genome Structure Popset Taxonomy
 Search
NCBI

UniGene
Homepage
FAQs
Help
Query Tips
Build Info
Library Browser
DDD
Download UniGene

Related Databases
Gene
HomoloGene
EST
SRA

NIH cDNA Projects
MGC | ZGC | XGC
Finding cDNAs
UGID:2729861     UniGene Hs.660543     Homo sapiens (human)   TLR8 Order cDNA clone, Links
Toll-like receptor 8 (TLR8)

Human protein-coding gene TLR8. Represented by 35 ESTs from 23 cDNA libraries. EST representation biased toward neonate. Corresponds to reference sequence NM_138636.4. [UniGene 2729861 - Hs.660543]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_619542.1 TLR8 gene product H. sapiens 100.0 1040
NP_001123944.1 toll-like receptor 8 precursor P. troglodytes 99.7 1040
NP_573475.2 toll-like receptor 8 precursor M. musculus 76.5 1031
XP_003199309.1 PREDICTED: toll-like receptor 7-like D. rerio 48.9 894
Other hits (2 of 19) [Show all]SpeciesId(%)Len(aa)
NP_001123899.1 toll-like receptor 8 precursor M. mulatta 97.5 1039
XP_003917456.1 PREDICTED: toll-like receptor 8 P. anubis 97.5 1058

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: neonate [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: placenta; brain; uncharacterized tissue; lung; vascular; blood; connective tissue; uterus; intestine; spleen; thymus; trachea; pineal gland; kidney
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: X
Map position: Xp22
UniSTS entry: Chr X RH93995
UniSTS entry: Chr X TLR8
UniSTS entry: Chr X TLR8_1092
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (13)

AY358296.1 Homo sapiens clone DNA42663 TLR8 (UNQ249) mRNA, complete cds PA
AF246971.1 Homo sapiens Toll-like receptor 8 (TLR8) mRNA, complete cds P
AF245703.1 Homo sapiens toll-like receptor 8 (TLR8) mRNA, complete cds P
BC101075.2 Homo sapiens toll-like receptor 8, mRNA (cDNA clone MGC:119599 IMAGE:40008788), complete cds P
BC101074.1 Homo sapiens toll-like receptor 8, mRNA (cDNA clone MGC:119598 IMAGE:40008787), complete cds P
BC101076.2 Homo sapiens toll-like receptor 8, mRNA (cDNA clone MGC:119600 IMAGE:40008792), complete cds P
BC101077.1 Homo sapiens toll-like receptor 8, mRNA (cDNA clone MGC:119601 IMAGE:40008793), complete cds P
AK314240.1 Homo sapiens cDNA, FLJ94985 P
AK307562.1 Homo sapiens cDNA, FLJ97510 P
NM_138636.4 Homo sapiens toll-like receptor 8 (TLR8), mRNA PA
AB445666.1 Homo sapiens TLR8 mRNA for toll-like receptor 8, complete cds P
AK297024.1 Homo sapiens cDNA FLJ56817 complete cds, highly similar to Toll-like receptor 8 precursor P
AK075117.1 Homo sapiens cDNA FLJ90636 fis, clone PLACE1003737, highly similar to Toll-like receptor 8 precursor P

EST sequences (10 of 35) [Show all sequences]

AA922616.1 Clone IMAGE:1474243 intestine 3' read A
BX106790.1 Clone IMAGp998B051158_;_IMAGE:486820 uterus A
AI261982.1 Clone IMAGE:1871754 intestine 3' read A
AI424196.1 Clone IMAGE:2103937 brain 3' read A
AI719285.1 Clone IMAGE:2320173 vascular 3' read A
AI890649.1 Clone IMAGE:2443064 uterus 3' read
BX391662.1 Clone CS0DI019YN01 placenta 3' read P
BX391663.1 Clone CS0DI019YN01 placenta 3' read P
CD365421.1 Clone UI-H-FT2-bjj-j-21-0-UI lung 3' read A
AW872374.1 Clone IMAGE:3009300 lung 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
NLM | NIH | UniGene | Privacy Statement | Disclaimer | NCBI Help