Inositol 1,4,5-trisphosphate receptor, type 3 (ITPR3)

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UGID:139124 UniGene Hs.65758 Homo sapiens (human) ITPR3

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Inositol 1,4,5-trisphosphate receptor, type 3 (ITPR3)

Human protein-coding gene ITPR3. Represented by 542 ESTs from 282 cDNA libraries. Corresponds to reference sequence NM_002224.3. [UniGene 139124 - Hs.65758]

SELECTED PROTEIN SIMILARITIES

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.

Best Hits and Hits from model organisms		Species	Id(%)	Len(aa)
NP_002215.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	ITPR3 gene product	H. sapiens	100.0	2670
XP_003897510.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: inositol 1,4,5-trisphosphate receptor type 3	P. anubis	99.6	2671
XP_002808429.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: LOW QUALITY PROTEIN: inositol 1,4,5-trisphosphate receptor type 3-like	M. mulatta	99.5	2647
NP_542120.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Itpr3 gene product	M. musculus	97.6	2669
NP_001084015.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	inositol 1,4,5-trisphosphate receptor, type 1	X. laevis	70.7	2681
XP_001921194.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: inositol 1,4,5-trisphosphate receptor type 1	D. rerio	69.7	2738
NP_730942.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	inositol 1,4,5,-tris-phosphate receptor, isoform A	D. melanogaster	61.0	2810
NP_001023171.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Protein ITR-1, isoform d	C. elegans	54.8	2809
Other hits (2 of 34) [Show all]		Species	Id(%)	Len(aa)
XP_518409.3 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: inositol 1,4,5-trisphosphate receptor type 3	P. troglodytes	99.4	2607
XP_538867.4 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: inositol 1,4,5-trisphosphate receptor type 3 isoform 1	C. lupus familiaris	98.8	2670

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

	EST Profile:	Approximate expression patterns inferred from EST sources. [Show more entries with profiles like this]
	GEO Profiles:	Experimental gene expression data (Gene Expression Omnibus).
	cDNA Sources:	intestine; lung; uncharacterized tissue; mixed; thyroid; brain; connective tissue; heart; lymph; lymph node; larynx; pancreas; testis; skin; pharynx; esophagus; eye; mammary gland; kidney; uterus; thymus; bone; cervix; blood; stomach; liver; tonsil; mouth; vascular; placenta; trachea; embryonic tissue; adrenal gland; bladder; amniotic fluid; ascites; nerve; ovary; muscle; prostate; ganglia; bone marrow; spleen; epididymis

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	6
Map position:	6p21
UniSTS entry:	Chr 6	RH46652	[Map Viewer]
UniSTS entry:	Chr 6	D6S2048
UniSTS entry:	Chr 6	STS-U01062	[Map Viewer]
UniSTS entry:	Chr 1	D10S16
UniSTS entry:	Chr 1	ha3079
UniSTS entry:		RH93741
UniSTS entry:	Chr 6	RH36260	[Map Viewer]

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (10)

AK128213.1	Homo sapiens cDNA FLJ46345 fis, clone TESTI4047305	P
AK126969.1	Homo sapiens cDNA FLJ45022 fis, clone BRAWH3016715
NM_002224.3	Homo sapiens inositol 1,4,5-trisphosphate receptor, type 3 (ITPR3), mRNA	PA
D26351.1	Homo sapiens mRNA for type 3 inositol 1,4,5-trisphosphate receptor, complete cds	P
AB209739.1	Homo sapiens mRNA for Inositol 1,4,5-trisphosphate receptor type 3 variant protein	P
U01062.1	Human type 3 inositol 1,4,5-trisphosphate receptor (ITPR3) mRNA, complete cds	P
BC146646.1	Homo sapiens inositol 1,4,5-triphosphate receptor, type 3, mRNA (cDNA clone IMAGE:40147135), partial cds	P
AK093524.1	Homo sapiens cDNA FLJ36205 fis, clone TESTI2028659, highly similar to Human type 3 inositol 1,4,5-trisphosphate receptor (ITPR3) mRNA	P
AL832807.1	Homo sapiens mRNA; cDNA DKFZp667O0323 (from clone DKFZp667O0323)	PA
BC041398.2	Homo sapiens cDNA clone IMAGE:5277696	A

Model sequences (1)

XR_171566.1

PREDICTED: Homo sapiens uncharacterized LOC101060688 (LOC101060688), misc_RNA

EST sequences (10 of 542) [Show all sequences]

AA865825.1	Clone IMAGE:1456770	kidney	3' read	A
AA968631.1	Clone IMAGE:1578361	mixed	3' read	P
AA969605.1	Clone IMAGE:1579142	mixed	3' read	P
AA970656.1	Clone IMAGE:1578986	mixed	3' read	P
AA983419.1	Clone IMAGE:1598810	uncharacterized tissue	3' read	A
AA994015.1	Clone IMAGE:1628933	mixed	3' read	P
AA994914.1	Clone IMAGE:1626913	mixed	3' read	A
AI026725.1	Clone IMAGE:1644153	testis	3' read
AI041004.1	Clone IMAGE:1641813	testis	3' read	A
AI074265.1	Clone IMAGE:1594441	intestine	3' read	A

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria