> Obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF (OBSCN)
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UGID:2726317     UniGene Hs.656999     Homo sapiens (human)   OBSCN Links
Obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF (OBSCN)

Human protein-coding gene OBSCN. Represented by 135 ESTs from 83 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 2726317 - Hs.656999]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001258152.2 OBSCN gene product H. sapiens 100.0 8922
NP_954603.3 obscurin isoform 2 M. musculus 72.4 7489
XP_001341205.4 PREDICTED: obscurin D. rerio 48.6 6434
Other hits (2 of 15) [Show all]SpeciesId(%)Len(aa)
XP_003893047.1 PREDICTED: LOW QUALITY PROTEIN: obscurin P. anubis 94.5 7956
NP_001095666.1 OBSCN gene product B. taurus 82.0 807

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: muscle; brain; larynx; embryonic tissue; intestine; mammary gland; uterus; testis; placenta; mixed; uncharacterized tissue; thyroid; lung; eye; heart; mouth; pharynx; nerve; prostate; thymus; trachea; connective tissue; kidney; ovary; bone
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 1
Map position: 1q42.13
UniSTS entry: Chr 1 SHGC-76459 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (19)

NM_052843.3 Homo sapiens obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF (OBSCN), transcript variant 1, mRNA PA
BC099731.1 Homo sapiens obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF, mRNA (cDNA clone IMAGE:40024803), complete cds P
BC098262.1 Homo sapiens obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF, mRNA (cDNA clone IMAGE:40024800), complete cds P
BC098118.1 Homo sapiens obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF, mRNA (cDNA clone IMAGE:40024799), complete cds P
BC098292.1 Homo sapiens obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF, mRNA (cDNA clone IMAGE:40024802), complete cds P
AB046859.2 Homo sapiens mRNA for KIAA1639 protein, partial cds P
AM231061.1 Homo sapiens partial mRNA for obscurin isoform B (OBSCN gene) P
BC114382.1 Homo sapiens obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF, mRNA (cDNA clone IMAGE:40024805), complete cds P
BC114461.1 Homo sapiens obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF, mRNA (cDNA clone IMAGE:40024804), complete cds P
NM_001098623.2 Homo sapiens obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF (OBSCN), transcript variant 2, mRNA PA
AJ002535.1 Homo sapiens mRNA for obscurin (OBSCN gene) P
DQ400343.1 Homo sapiens obscurin isoform B (OBSCN) mRNA, partial cds, alternatively spliced P
AK097489.1 Homo sapiens cDNA FLJ40170 fis, clone TESTI2016848, weakly similar to H.sapiens mRNA for titin protein P
AL833724.1 Homo sapiens mRNA; cDNA DKFZp666E245 (from clone DKFZp666E245) PA
AL832357.1 Homo sapiens mRNA; cDNA DKFZp451F056 (from clone DKFZp451F056) PA
BC034746.1 Homo sapiens obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF, mRNA (cDNA clone IMAGE:5191938), with apparent retained intron PA
AB046776.1 Homo sapiens mRNA for KIAA1556 protein, partial cds P
AK294019.1 Homo sapiens cDNA FLJ52598 complete cds P
NM_001271223.2 Homo sapiens obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF (OBSCN), transcript variant IC, mRNA PA

EST sequences (10 of 135) [Show all sequences]

AI080136.1 Clone IMAGE:1678536 mixed 3' read A
AI128717.1 Clone IMAGE:1691379 heart 3' read A
BX088811.1 Clone IMAGp998F083513_;_IMAGE:1391239 testis
R45814.1 Clone a495-f heart
R45853.1 Clone c529-f heart
AI478779.1 Clone IMAGE:2157530 mixed 3' read
F24617.1 Clone s4000016D08 muscle A
F26294.1 Clone s4000052C06 muscle
F27978.1 Clone s4000029B04 muscle
F28086.1 Clone s3000002A03 muscle


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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