> Ribosomal protein S6 kinase, 90kDa, polypeptide 2 (RPS6KA2)
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UGID:2724595     UniGene Hs.655277     Homo sapiens (human)   RPS6KA2
Ribosomal protein S6 kinase, 90kDa, polypeptide 2 (RPS6KA2)

Human protein-coding gene RPS6KA2. Represented by 405 ESTs from 183 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 2724595 - Hs.655277]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001006933.1 RPS6KA2 gene product H. sapiens 100.0 740
NP_035429.1 Rps6ka2 gene product M. musculus 97.4 732
XP_699952.2 PREDICTED: ribosomal protein S6 kinase, polypeptide 2-like D. rerio 94.7 732
NP_001084222.1 ribosomal protein S6 kinase, 90kDa, polypeptide 3 X. laevis 89.2 736
NP_001021602.1 Protein RSKN-1, isoform c C. elegans 72.6 722
NP_523437.2 ribosomal protein S6 kinase II, isoform A D. melanogaster 71.8 772
XP_965297.1 AGC family protein serine/threonine kinase domain-containing protein N. crassa 54.0 337
XP_001693559.1 ribosomal protein S6 kinase C. reinhardtii 52.0 244
NP_187484.1 serine/threonine protein kinase 2 A. thaliana 51.9 318
NP_012755.1 Tpk3p S. cerevisiae 50.8 250
Other hits (2 of 65) [Show all]SpeciesId(%)Len(aa)
XP_003311634.1 PREDICTED: ribosomal protein S6 kinase alpha-2 P. troglodytes 99.3 754
XP_003898442.1 PREDICTED: ribosomal protein S6 kinase alpha-2 P. anubis 98.9 734

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; mixed; uncharacterized tissue; eye; lung; testis; mammary gland; prostate; thyroid; connective tissue; adrenal gland; muscle; pancreas; embryonic tissue; pituitary gland; kidney; ovary; placenta; intestine; liver; trachea; thymus; blood; skin; lymph node; uterus; salivary gland; parathyroid; ascites; mouth; heart; larynx; vascular; spleen; ganglia; umbilical cord; bone; stomach
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 6
Map position: 6q27
UniSTS entry: Chr 6 A002B12 [Map Viewer]
UniSTS entry: Chr 6 RH45609 [Map Viewer]
UniSTS entry: Chr 6 STS-W96228
UniSTS entry: Chr 6 WI-17352 [Map Viewer]
UniSTS entry: Chr 6 RH121975
UniSTS entry: Chr 6 RPS6KA2__5527
UniSTS entry: Chr 6 RH46839 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (14)

NM_001006932.1 Homo sapiens ribosomal protein S6 kinase, 90kDa, polypeptide 2 (RPS6KA2), transcript variant 2, mRNA P
AB209116.1 Homo sapiens mRNA for ribosomal protein S6 kinase, 90kDa, polypeptide 2 isoform b variant protein P
X85106.1 H.sapiens mRNA for ribosomal S6 kinase P
AB073884.1 Homo sapiens primary neuroblastoma cDNA, clone:Nbla00832, full insert sequence
NM_021135.4 Homo sapiens ribosomal protein S6 kinase, 90kDa, polypeptide 2 (RPS6KA2), transcript variant 1, mRNA P
BC002363.2 Homo sapiens ribosomal protein S6 kinase, 90kDa, polypeptide 2, mRNA (cDNA clone MGC:8629 IMAGE:2961482), complete cds PA
AK027727.1 Homo sapiens cDNA FLJ14821 fis, clone OVARC1000556, highly similar to RIBOSOMAL PROTEIN S6 KINASE II ALPHA 2 (EC 2.7.1.-) P
AK310428.1 Homo sapiens cDNA, FLJ17470 P
AK307470.1 Homo sapiens cDNA, FLJ97418 P
AK095751.1 Homo sapiens cDNA FLJ38432 fis, clone FEBRA2014417, highly similar to Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1) P
BC011189.1 Homo sapiens ribosomal protein S6 kinase, 90kDa, polypeptide 2, mRNA (cDNA clone IMAGE:4151609) A
AF140710.1 Homo sapiens T complex responder 2 mRNA sequence A
L07598.1 Homo sapiens ribosomal protein S6 kinase 2 (RPS6KA2) mRNA, partial cds P
AK295674.1 Homo sapiens cDNA FLJ55331 complete cds, highly similar to Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1) P

EST sequences (10 of 405) [Show all sequences]

AI016296.1 Clone IMAGE:1622320 embryonic tissue 3' read A
AI016840.1 Clone IMAGE:1639117 testis 3' read A
AI017598.1 Clone IMAGE:1627710 mixed 3' read A
AI018233.1 Clone IMAGE:1626744 mixed 3' read
AI056244.1 Clone IMAGE:1673144 mixed 3' read
AI141035.1 Clone IMAGE:1678118 mixed 3' read
CB048797.1 Clone IMAGE:3270822 prostate 3' read A
CB048798.1 Clone IMAGE:3270822 prostate 5' read A
AI217287.1 Clone IMAGE:1845683 mixed 3' read A
AI249270.1 Clone IMAGE:2005069 pancreas 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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