Metallothionein 1A (MT1A)

Restricted Expression:

colorectal tumor [show more like this]

adult [show more like this]

EST Profile:

Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]

GEO Profiles:

Experimental gene expression data (Gene Expression Omnibus).

cDNA Sources:

intestine; lung; mixed; liver; eye; uncharacterized tissue; adipose tissue; connective tissue; uterus

NCBI

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Finding cDNAs

UGID:2724517 UniGene Hs.655199 Homo sapiens (human) MT1A

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Metallothionein 1A (MT1A)

Human protein-coding gene MT1A. Represented by 57 ESTs from 14 cDNA libraries. EST representation biased toward colorectal tumor; adult. Corresponds to reference sequence NM_005946.2. [UniGene 2724517 - Hs.655199]

SELECTED PROTEIN SIMILARITIES

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.

Best Hits and Hits from model organisms		Species	Id(%)	Len(aa)
NP_005937.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	MT1A gene product	H. sapiens	100.0	60
Other hits (		Species	Id(%)	Len(aa)
XP_003916958.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: metallothionein-1E isoform 1	P. anubis	85.9	70
XP_003308881.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: metallothionein-2-like	P. troglodytes	79.5	77

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	16
Map position:	16q13
UniSTS entry:	Chr 16	D16S3240

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (3)

NM_005946.2	Homo sapiens metallothionein 1A (MT1A), mRNA	PA
AY028617.1	Homo sapiens metallothionein 1S (MT1S) mRNA, complete cds	P
BC029475.1	Homo sapiens metallothionein 1A, mRNA (cDNA clone MGC:32848 IMAGE:4723818), complete cds	PA

EST sequences (10 of 57) [Show all sequences]

CD366274.1	Clone UI-H-FT1-bjt-k-09-0-UI	lung	3' read	A
CD370351.1	Clone UI-H-FT1-bkb-j-15-0-UI	lung	3' read	A
AW952177.1		uncharacterized tissue
CR735494.1	Clone IMAGp958K091519_;_IMAGE:4694912	lung	5' read	P
CV377533.1		intestine
T27991.1		adipose tissue	5' read	P
H60607.1	Clone IMAGE:208150	mixed	5' read
H81518.1	Clone IMAGE:230645	mixed	5' read
BF766236.1		intestine
BF766237.1		intestine

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria