> Sorbin and SH3 domain containing 2 (SORBS2)
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UGID:2724461     UniGene Hs.655143     Homo sapiens (human)   SORBS2 Order cDNA clone, Links
Sorbin and SH3 domain containing 2 (SORBS2)

Human protein-coding gene SORBS2. Represented by 706 ESTs from 246 cDNA libraries. Corresponds to 9 reference sequences (different isoforms). [UniGene 2724461 - Hs.655143]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001257700.1 SORBS2 gene product H. sapiens 100.0 1199
NP_766340.4 Sorbs2 gene product M. musculus 92.4 1195
XP_691857.4 PREDICTED: sorbin and SH3 domain-containing protein 2 D. rerio 61.4 1060
NP_001137639.1 CAP, isoform N D. melanogaster 46.3 255
Other hits (2 of 25) [Show all]SpeciesId(%)Len(aa)
XP_001164942.1 PREDICTED: sorbin and SH3 domain-containing protein 2 isoform 24 P. troglodytes 98.8 1201
XP_001087467.1 PREDICTED: sorbin and SH3 domain-containing protein 2 isoform 6 M. mulatta 98.2 1198

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; heart; uncharacterized tissue; vascular; mouth; pancreas; prostate; mixed; placenta; uterus; embryonic tissue; eye; mammary gland; kidney; testis; intestine; stomach; trachea; adipose tissue; thyroid; lung; connective tissue; liver; spleen; cervix; muscle; adrenal gland; bladder; lymph; ear; pharynx; parathyroid; pineal gland; thymus; ovary; skin; bone marrow; esophagus; nerve; blood
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 4
Map position: 4q35.1
UniSTS entry: Chr 4 D4S3275 [Map Viewer]
UniSTS entry: Chr 4 WI-20258 [Map Viewer]
UniSTS entry: Chr 4 D4S2537E [Map Viewer]
UniSTS entry: Chr 4 D4S2823 [Map Viewer]
UniSTS entry: Chr 4 SHGC-67725
UniSTS entry: Chr 4 SHGC-31331 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (25)

AB018320.1 Homo sapiens mRNA for KIAA0777 protein, partial cds P
NM_003603.6 Homo sapiens sorbin and SH3 domain containing 2 (SORBS2), transcript variant 1, mRNA P
AK000782.1 Homo sapiens cDNA FLJ20775 fis, clone COL06005 A
NM_021069.4 Homo sapiens sorbin and SH3 domain containing 2 (SORBS2), transcript variant 2, mRNA P
AK225812.1 Homo sapiens mRNA for Arg/Abl-interacting protein 2 isoform 1 variant, clone: FCC129E07 PA
AK225327.1 Homo sapiens mRNA for Arg/Abl-interacting protein 2 isoform 1 variant, clone: HEP12372 PA
BC122526.1 Homo sapiens sorbin and SH3 domain containing 2, mRNA (cDNA clone IMAGE:40017087), **** WARNING: chimeric clone **** P
EF139852.1 Homo sapiens clone 2-3 sorbin and SH3 domain containing 2 splice variant (SORBS2) mRNA, partial sequence; alternatively spliced P
BC011883.1 Homo sapiens sorbin and SH3 domain containing 2, mRNA (cDNA clone MGC:20120 IMAGE:3677070), complete cds PA
AK056758.1 Homo sapiens cDNA FLJ32196 fis, clone PLACE6002668, highly similar to Homo sapiens sorbin and SH3 domain containing 2 (SORBS2), transcript variant 1, mRNA P
AK056628.1 Homo sapiens cDNA FLJ32066 fis, clone OCBBF1000091, highly similar to Homo sapiens sorbin and SH3 domain containing 2 (SORBS2), transcript variant 2, mRNA P
AF049885.1 Homo sapiens Arg/Abl-interacting protein ArgBP2b (ArgBP2b) mRNA, partial cds P
AK304653.1 Homo sapiens cDNA FLJ54581 complete cds, highly similar to Homo sapiens sorbin and SH3 domain containing 2 (SORBS2), transcript variant 1, mRNA P
AK296461.1 Homo sapiens cDNA FLJ53348 complete cds, highly similar to Homo sapiens sorbin and SH3 domain containing 2 (SORBS2), transcript variant 2, mRNA P
AK295742.1 Homo sapiens cDNA FLJ55213 complete cds, highly similar to Rattus norvegicus Arg/Abl-interacting protein ArgBP2 (Argbp2), mRNA P
AK293400.1 Homo sapiens cDNA FLJ56051 complete cds, highly similar to Homo sapiens sorbin and SH3 domain containing 2 (SORBS2), transcript variant 1, mRNA P
NM_001145675.1 Homo sapiens sorbin and SH3 domain containing 2 (SORBS2), transcript variant 8, mRNA P
NM_001145674.1 Homo sapiens sorbin and SH3 domain containing 2 (SORBS2), transcript variant 7, mRNA P
NM_001145673.1 Homo sapiens sorbin and SH3 domain containing 2 (SORBS2), transcript variant 6, mRNA P
NM_001145672.1 Homo sapiens sorbin and SH3 domain containing 2 (SORBS2), transcript variant 5, mRNA P
NM_001145671.2 Homo sapiens sorbin and SH3 domain containing 2 (SORBS2), transcript variant 4, mRNA P
NM_001145670.1 Homo sapiens sorbin and SH3 domain containing 2 (SORBS2), transcript variant 3, mRNA P
BC035329.1 Homo sapiens sorbin and SH3 domain containing 2, mRNA (cDNA clone IMAGE:5194874) A
NM_001270771.1 Homo sapiens sorbin and SH3 domain containing 2 (SORBS2), transcript variant 9, mRNA P
AF049884.1 Homo sapiens Arg/Abl-interacting protein ArgBP2a (ArgBP2a) mRNA, complete cds P

EST sequences (10 of 706) [Show all sequences]

AA985252.1 Clone IMAGE:1629443 brain 3' read
AA987658.1 Clone IMAGE:1604351 lung 3' read P
AA999835.1 Clone IMAGE:1636352 kidney 3' read A
AI000340.1 Clone IMAGE:1637002 kidney 3' read P
AI014967.1 Clone IMAGE:1640741 testis 3' read
AI038392.1 Clone IMAGE:1657018 mixed 3' read P
AI039729.1 Clone IMAGE:1658176 embryonic tissue 3' read
AA947604.1 Clone IMAGE:1590202 kidney 3' read
AI075230.1 Clone IMAGE:1667568 parathyroid 3' read
AI093881.1 Clone IMAGE:1688295 mixed 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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