> DENN/MADD domain containing 2C (DENND2C)
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UGID:2724246     UniGene Hs.654928     Homo sapiens (human)   DENND2C Links
DENN/MADD domain containing 2C (DENND2C)

Human protein-coding gene DENND2C. Represented by 51 ESTs from 31 cDNA libraries. EST representation biased toward blastocyst. Corresponds to 2 reference sequences (different isoforms). [UniGene 2724246 - Hs.654928]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001243333.1 DENND2C gene product H. sapiens 100.0 927
XP_524806.2 PREDICTED: DENN domain-containing protein 2C isoform 2 P. troglodytes 99.7 927
NP_808525.2 Dennd2c gene product M. musculus 88.3 919
XP_001919086.3 PREDICTED: DENN domain-containing protein 2C D. rerio 56.6 894
NP_001086599.1 DENN/MADD domain containing 2D X. laevis 54.7 411
Other hits (2 of 21) [Show all]SpeciesId(%)Len(aa)
XP_002801777.1 PREDICTED: DENN domain-containing protein 2C-like M. mulatta 98.3 412
XP_003892483.1 PREDICTED: DENN domain-containing protein 2C P. anubis 98.1 926

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: blastocyst [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: testis; liver; embryonic tissue; muscle; brain; mouth; intestine; heart; lung; kidney; mixed; larynx; skin; prostate; eye; uncharacterized tissue
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 1
Map position: 1p13.2
UniSTS entry: Chr 1 SHGC-75354 [Map Viewer]
UniSTS entry: Chr 1 RH36905
UniSTS entry: Chr 1 D11S2921
UniSTS entry: Chr 1 GDB:631802
UniSTS entry: RH99209
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (7)

BX649075.1 Homo sapiens mRNA; cDNA DKFZp779P1149 (from clone DKFZp779P1149) PA
BX647950.1 Homo sapiens mRNA; cDNA DKFZp686G0351 (from clone DKFZp686G0351) PA
AK124287.1 Homo sapiens cDNA FLJ42293 fis, clone TLIVE2007919, moderately similar to Human p70 (ST5) mRNA, alternatively spliced P
NM_198459.3 Homo sapiens DENN/MADD domain containing 2C (DENND2C), transcript variant 2, mRNA P
CR749576.1 Homo sapiens mRNA; cDNA DKFZp686N1631 (from clone DKFZp686N1631) PA
AK308302.1 Homo sapiens cDNA, FLJ98250 P
NM_001256404.1 Homo sapiens DENN/MADD domain containing 2C (DENND2C), transcript variant 1, mRNA P

EST sequences (10 of 51) [Show all sequences]

AI017969.1 Clone IMAGE:1627792 mixed 3' read A
AI142310.1 Clone IMAGE:1839806 testis 5' read
AI142348.1 Clone IMAGE:1839902 testis 5' read
AI147339.1 Clone IMAGE:1839902 testis 3' read A
BX118299.1 Clone IMAGp998H154500_;_IMAGE:1839806 testis
AI214451.1 Clone IMAGE:1839401 testis 3' read
AI341679.1 Clone IMAGE:1939170 embryonic tissue 3' read A
AI916261.1 Clone IMAGE:2379363 kidney 3' read
AI928426.1 Clone IMAGE:2460434 prostate 3' read A
CD358410.1 Clone IMAGE:30389241 testis 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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