CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 (CDS1)

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UGID:2724217 UniGene Hs.654899 Homo sapiens (human) CDS1

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CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 (CDS1)

Human protein-coding gene CDS1. Represented by 216 ESTs from 102 cDNA libraries. Corresponds to reference sequence NM_001263.3. [UniGene 2724217 - Hs.654899]

SELECTED PROTEIN SIMILARITIES

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.

Best Hits and Hits from model organisms		Species	Id(%)	Len(aa)
XP_517179.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: phosphatidate cytidylyltransferase 1 isoform 2	P. troglodytes	100.0	460
NP_001254.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	CDS1 gene product	H. sapiens	100.0	460
XP_003898718.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: phosphatidate cytidylyltransferase 1	P. anubis	99.8	460
NP_775546.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Cds1 gene product	M. musculus	98.3	460
XP_001341899.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: phosphatidate cytidylyltransferase 1	D. rerio	85.8	444
NP_524661.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	CDP diglyceride synthetase	D. melanogaster	67.2	442
NP_501298.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Protein C33H5.18, isoform b	C. elegans	60.3	450
NP_974591.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	cytidinediphosphate diacylglycerol synthase 2	A. thaliana	52.0	269
XP_001691838.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	CDP-DAG synthetase	C. reinhardtii	51.5	237
XP_958709.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	phosphatidate cytidylyltransferase	N. crassa	50.0	234
NP_009585.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	phosphatidate cytidylyltransferase	S. cerevisiae	49.8	233
Other hits (2 of 57) [Show all]		Species	Id(%)	Len(aa)
XP_544962.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: phosphatidate cytidylyltransferase 1	C. lupus familiaris	98.9	460
XP_001915418.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: phosphatidate cytidylyltransferase 1	E. caballus	98.9	460

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

	EST Profile:	Approximate expression patterns inferred from EST sources. [Show more entries with profiles like this]
	GEO Profiles:	Experimental gene expression data (Gene Expression Omnibus).
	cDNA Sources:	testis; placenta; kidney; lung; brain; intestine; mixed; pancreas; uncharacterized tissue; ovary; prostate; embryonic tissue; ear; parathyroid; trachea; mouth; ascites; eye; mammary gland; liver; thyroid; uterus; adrenal gland; pharynx; bone

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	4
Map position:	4q21.23
UniSTS entry:	Chr 4	SHGC-59792
UniSTS entry:	Chr 4	SHGC-59679
UniSTS entry:	Chr 4	WI-11924
UniSTS entry:	Chr 4	SHGC-67258	[Map Viewer]

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (8)

NM_001263.3	Homo sapiens CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 (CDS1), mRNA	PA
AY312584.1	Homo sapiens CDP-diacylglycerol synthase 1 mRNA, partial sequence, alternatively spliced	P
BC074881.2	Homo sapiens CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1, mRNA (cDNA clone MGC:103857 IMAGE:30915239), complete cds	P
BC074833.2	Homo sapiens CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1, mRNA (cDNA clone MGC:104094 IMAGE:30915545), complete cds	P
AK026697.1	Homo sapiens cDNA: FLJ23044 fis, clone LNG02454	A
AK314245.1	Homo sapiens cDNA, FLJ94990, Homo sapiens CDP-diacylglycerol synthase (phosphatidatecytidylyltransferase) 1 (CDS1), mRNA	P
U65887.1	Human CDP-diacylglycerol synthase mRNA, complete cds	PA
U60808.1	Human CDP-diacylglycerol synthase (CDS) mRNA, complete cds	PA

EST sequences (10 of 216) [Show all sequences]

BX106095.1	Clone IMAGp998E06196_;_IMAGE:136685	placenta
BX114169.1	Clone IMAGp998N02188_;_IMAGE:133825	placenta		PA
AI188319.1	Clone IMAGE:1723573	placenta	3' read
AI192361.1	Clone IMAGE:1722624	placenta	3' read
AI221018.1	Clone IMAGE:1758553	placenta	3' read
R27669.1	Clone IMAGE:134507	placenta	5' read
R27966.1	Clone IMAGE:133825	placenta	3' read	P
AI262674.1	Clone IMAGE:1870938	intestine	3' read
AI264155.1	Clone IMAGE:1867877	kidney	3' read	P
CB157789.1	Clone L18POOL1n1-4-C02	liver	5' read	P

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria