> RAB3 GTPase activating protein subunit 2 (non-catalytic) (RAB3GAP2)
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UGID:2724167     UniGene Hs.654849     Homo sapiens (human)   RAB3GAP2
RAB3 GTPase activating protein subunit 2 (non-catalytic) (RAB3GAP2)

Human protein-coding gene RAB3GAP2. Represented by 296 ESTs from 175 cDNA libraries. Corresponds to reference sequence NM_012414.3. [UniGene 2724167 - Hs.654849]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_514211.2 PREDICTED: rab3 GTPase-activating protein non-catalytic subunit P. troglodytes 100.0 1392
NP_036546.2 RAB3GAP2 gene product H. sapiens 100.0 1392
XP_001103011.1 PREDICTED: rab3 GTPase-activating protein non-catalytic subunit M. mulatta 99.5 1392
NP_001157226.1 Rab3gap2 gene product M. musculus 92.1 1385
NP_001082272.1 aurora kinase A-B X. laevis 82.0 222
NP_001004528.1 rab3 GTPase-activating protein non-catalytic subunit D. rerio 67.6 1266
XP_001692272.1 aurora-like kinase C. reinhardtii 67.0 221
NP_180159.2 serine/threonine-protein kinase aurora-2 A. thaliana 63.0 235
NP_491714.1 Protein AIR-2 C. elegans 61.0 218
XP_957232.1 serine/threonine-protein kinase 6 N. crassa 58.1 227
NP_477336.1 IplI-aurora-like kinase D. melanogaster 51.6 223
NP_015115.1 Ipl1p S. cerevisiae 47.1 223
Other hits (2 of 59) [Show all]SpeciesId(%)Len(aa)
XP_003893142.1 PREDICTED: rab3 GTPase-activating protein non-catalytic subunit P. anubis 99.3 1351
XP_536122.2 PREDICTED: rab3 GTPase-activating protein non-catalytic subunit C. lupus familiaris 97.0 1393

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; uncharacterized tissue; embryonic tissue; lymph node; muscle; thyroid; testis; kidney; lung; mammary gland; mixed; ovary; placenta; pituitary gland; mouth; skin; connective tissue; eye; intestine; pancreas; vascular; liver; trachea; uterus; esophagus; adrenal gland; stomach; tonsil; cervix; blood; bladder; ascites; bone; ear; prostate; heart; bone marrow; ganglia; parathyroid; larynx
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 1
Map position: 1q41
UniSTS entry: Chr 1 SHGC-76387 [Map Viewer]
UniSTS entry: Chr 1 SHGC-76377 [Map Viewer]
UniSTS entry: Chr 1 A005E47 [Map Viewer]
UniSTS entry: Chr 1 SHGC-76378 [Map Viewer]
UniSTS entry: Chr 1 SHGC-24046
UniSTS entry: Chr 1 RH45736
UniSTS entry: Chr 1 RH69283 [Map Viewer]
UniSTS entry: Chr 20 SHGC-53807
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (13)

AF004828.1 Homo sapiens rab3-GAP regulatory domain mRNA, complete cds P
AB020646.2 Homo sapiens mRNA for KIAA0839 protein, partial cds P
BC050630.1 Homo sapiens cDNA clone IMAGE:5580410, containing frame-shift errors PA
AL117631.1 Homo sapiens mRNA; cDNA DKFZp434D245 (from clone DKFZp434D245); partial cds PA
NM_012414.3 Homo sapiens RAB3 GTPase activating protein subunit 2 (non-catalytic) (RAB3GAP2), mRNA P
BC098383.1 Homo sapiens cDNA clone IMAGE:30520261, containing frame-shift errors PA
AK021928.1 Homo sapiens cDNA FLJ11866 fis, clone HEMBA1006973, highly similar to Homo sapiens rab3-GAP regulatory domain mRNA P
AF255648.1 Homo sapiens rGAP-iso mRNA, complete cds P
AK027485.1 Homo sapiens cDNA FLJ14579 fis, clone NT2RM4001203, highly similar to Rab3 GTPase-activating protein non-catalytic subunit P
BC131573.1 Homo sapiens cDNA clone IMAGE:40108635 P
BC146760.1 Homo sapiens RAB3 GTPase activating protein subunit 2 (non-catalytic), mRNA (cDNA clone MGC:166829 IMAGE:9007199), complete cds PA
AK291234.1 Homo sapiens cDNA FLJ78421 complete cds, highly similar to Homo sapiens RAB3 GTPase activating protein subunit 2 (non-catalytic) (RAB3GAP2), mRNA P
BC036513.1 Homo sapiens cDNA clone IMAGE:4822549, containing frame-shift errors PA

EST sequences (10 of 296) [Show all sequences]

AI078390.1 Clone IMAGE:1676725 embryonic tissue 3' read
AI139918.1 Clone IMAGE:1737909 testis 3' read P
BX101511.1 Clone IMAGp998M021165_;_IMAGE:489769 uterus
AI264708.1 Clone IMAGE:2005343 pancreas 3' read A
CB161508.1 Clone L17N670205n1-34-E09 liver 5' read
AI268997.1 Clone IMAGE:1864567 kidney 3' read P
CB149506.1 Clone L15CKK1-50-H10 liver 5' read
AA888624.1 Clone IMAGE:1252182 bone A
AI298790.1 Clone IMAGE:1896100 lung 3' read P
R36176.1 Clone IMAGE:136804 placenta 5' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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