> MAD1 mitotic arrest deficient-like 1 (yeast) (MAD1L1)
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UGID:2724156     UniGene Hs.654838     Homo sapiens (human)   MAD1L1 Order cDNA clone, Links
MAD1 mitotic arrest deficient-like 1 (yeast) (MAD1L1)

Human protein-coding gene MAD1L1. Represented by 479 ESTs from 191 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 2724156 - Hs.654838]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_003541.2 MAD1L1 gene product H. sapiens 100.0 717
XP_518933.2 PREDICTED: mitotic spindle assembly checkpoint protein MAD1 isoform 4 P. troglodytes 99.9 717
NP_034882.2 Mad1l1 gene product M. musculus 85.0 715
NP_001080972.1 spindle checkpoint protein Xmad1 X. laevis 67.0 717
NP_957206.2 mad1l1 gene product D. rerio 61.2 716
Other hits (2 of 20) [Show all]SpeciesId(%)Len(aa)
XP_003895703.1 PREDICTED: mitotic spindle assembly checkpoint protein MAD1 isoform 1 P. anubis 99.2 717
XP_001102100.1 PREDICTED: mitotic spindle assembly checkpoint protein MAD1 M. mulatta 95.7 799

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; connective tissue; testis; skin; uncharacterized tissue; larynx; vascular; lymph node; spleen; mammary gland; thymus; liver; placenta; muscle; heart; kidney; prostate; mixed; eye; mouth; uterus; tonsil; blood; pancreas; trachea; embryonic tissue; lung; ovary; ascites; bone; intestine; esophagus; lymph; cervix; bone marrow; salivary gland; adipose tissue; stomach; nerve
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 7
Map position: 7p22
UniSTS entry: Chr 7 RH71224 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (12)

NM_003550.2 Homo sapiens MAD1 mitotic arrest deficient-like 1 (yeast) (MAD1L1), transcript variant 1, mRNA PA
U33822.1 Human tax1-binding protein TXBP181 mRNA, complete cds P
AF123318.1 Homo sapiens mitotic checkpoint protein (MAD1) mRNA, complete cds P
AF083811.1 Homo sapiens mitotic checkpoint protein isoform MAD1a (MAD1) mRNA, complete cds P
NM_001013837.1 Homo sapiens MAD1 mitotic arrest deficient-like 1 (yeast) (MAD1L1), transcript variant 3, mRNA PA
NM_001013836.1 Homo sapiens MAD1 mitotic arrest deficient-like 1 (yeast) (MAD1L1), transcript variant 2, mRNA PA
BC009964.2 Homo sapiens MAD1 mitotic arrest deficient-like 1 (yeast), mRNA (cDNA clone MGC:15273 IMAGE:4299982), complete cds PA
AK314227.1 Homo sapiens cDNA, FLJ94966 P
AK310831.1 Homo sapiens cDNA, FLJ17873 P
AK310481.1 Homo sapiens cDNA, FLJ17523 P
AK090959.1 Homo sapiens cDNA FLJ33640 fis, clone BRAMY2023482, highly similar to Mitotic spindle assembly checkpoint protein MAD1 P
BC018870.2 Homo sapiens MAD1 mitotic arrest deficient-like 1 (yeast), mRNA (cDNA clone IMAGE:3605329) PA

EST sequences (10 of 479) [Show all sequences]

AI085628.1 Clone IMAGE:1678095 mixed 3' read
BX116761.1 Clone IMAGp998I19286_;_IMAGE:51768 brain PA
AI190950.1 Clone IMAGE:1732557 heart 3' read A
AI219881.1 Clone IMAGE:1838290 testis 3' read A
CB124451.1 Clone L5HLK1s1-10-F05 liver 5' read
CB125187.1 Clone L5HLK1s1-12-C09 liver 5' read P
CB125343.1 Clone L5HLK1s1-13-B04 liver 5' read P
CB126239.1 Clone L5HLK1s1-31-C10 liver 5' read
CB126509.1 Clone L5HLK1s1-19-F01 liver 5' read
CB124149.1 Clone L5HLK1s1-11-B05 liver 5' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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