> Bromodomain and WD repeat domain containing 1 (BRWD1)
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UGID:2724058     UniGene Hs.654740     Homo sapiens (human)   BRWD1 Links
Bromodomain and WD repeat domain containing 1 (BRWD1)

Human protein-coding gene BRWD1. Represented by 497 ESTs from 214 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 2724058 - Hs.654740]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_061836.2 BRWD1 gene product H. sapiens 100.0 2319
XP_001170924.1 PREDICTED: bromodomain and WD repeat-containing protein 1 isoform 1 P. troglodytes 99.7 2319
NP_660107.2 Brwd1 gene product M. musculus 88.2 2300
XP_001920441.3 PREDICTED: bromodomain and WD repeat-containing protein 1 D. rerio 59.5 2183
NP_732982.1 BRWD3 D. melanogaster 50.5 917
Other hits (2 of 34) [Show all]SpeciesId(%)Len(aa)
XP_001108760.2 PREDICTED: bromodomain and WD repeat-containing protein 1 isoform 2 M. mulatta 98.9 2268
NP_001162556.1 bromodomain and WD repeat-containing protein 1 P. anubis 98.7 2319

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; mixed; placenta; uncharacterized tissue; mammary gland; lung; kidney; pancreas; vascular; eye; thymus; intestine; bone; trachea; skin; heart; blood; lymph node; muscle; liver; embryonic tissue; lymph; adrenal gland; spleen; uterus; stomach; prostate; mouth; salivary gland; ear; connective tissue; ovary; spinal cord; cervix; thyroid; nerve; bone marrow
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 21
Map position: 21q22.2
UniSTS entry: Chr 21 REN20020
UniSTS entry: Chr 21 SHGC-87637 [Map Viewer]
UniSTS entry: Chr 21 NIB1959
UniSTS entry: Chr 21 D21S1828
UniSTS entry: Chr 21 D21S1817
UniSTS entry: Chr 12 REN20021
UniSTS entry: Chr 21 STS-R31946
UniSTS entry: Chr 12 RH66958
UniSTS entry: Chr 12 G32288
UniSTS entry: Chr 21 REN19558
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (30)

BC047058.1 Homo sapiens bromodomain and WD repeat domain containing 1, mRNA (cDNA clone IMAGE:5287569) A
AL109785.1 Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 273140 A
AL109786.1 Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 814975 A
AK125906.1 Homo sapiens cDNA FLJ43918 fis, clone TESTI4011745, highly similar to WD-repeat protein 9 P
BC064602.1 Homo sapiens bromodomain and WD repeat domain containing 1, mRNA (cDNA clone IMAGE:5785347), complete cds PA
AK002177.1 Homo sapiens cDNA FLJ11315 fis, clone PLACE1010148 P
AL162036.1 Homo sapiens mRNA; cDNA DKFZp434B249 (from clone DKFZp434B249) A
NM_001007246.2 Homo sapiens bromodomain and WD repeat domain containing 1 (BRWD1), transcript variant 3, mRNA PA
AB080593.1 Homo sapiens WDR9 mRNA for WD repeat protein, WDR9-exon17-short, partial cds P
AB080592.1 Homo sapiens WDR9 mRNA for WD repeat protein, WDR9-exon16-short, partial cds P
AB080591.1 Homo sapiens WDR9 mRNA for WD repeat protein, WDR9-exon21-del, partial cds P
AB080590.1 Homo sapiens WDR9 mRNA for WD repeat protein, WDR9-exon35-del, partial cds P
AB080589.1 Homo sapiens WDR9 mRNA for WD repeat protein, WDR9-exon19-short, partial cds P
AB080588.1 Homo sapiens WDR9 mRNA for WD repeat protein, WDR9-exon19-del, partial cds P
AB080587.1 Homo sapiens WDR9 mRNA for WD repeat protein, WDR9-form2, complete cds PA
AB080586.1 Homo sapiens WDR9 mRNA for WD repeat protein, WDR9-form1, complete cds PA
AJ238555.1 Homo sapiens mRNA for partial 3'UTR, sequence 2
AJ238556.1 Homo sapiens mRNA for partial 3'UTR, sequence 3 P
NM_018963.4 Homo sapiens bromodomain and WD repeat domain containing 1 (BRWD1), transcript variant 1, mRNA PA
AJ292466.1 Homo sapiens mRNA for WDR9 protein (WDR9 gene), form B P
AJ292465.1 Homo sapiens mRNA for WDR9 protein (WDR9 gene), form A P
BC142986.1 Homo sapiens bromodomain and WD repeat domain containing 1, mRNA (cDNA clone IMAGE:8860432), complete cds PA
NM_033656.3 Homo sapiens bromodomain and WD repeat domain containing 1 (BRWD1), transcript variant 2, mRNA PA
AJ238214.2 Homo sapiens mRNA originating from the Down syndrome chromosomal region-2 (21q22.3) encoding hypothetical protein P
BC031545.1 Homo sapiens bromodomain and WD repeat domain containing 1, mRNA (cDNA clone IMAGE:4388745) A
AJ238573.1 Homo sapiens mRNA for partial 3'UTR, sequence 4
AJ002574.1 Homo sapiens mRNA; transcriptional unit N144, 5' end
AJ222636.1 Homo sapiens partial human cDNA (660 bp) P
AJ222635.1 Homo sapiens partial human cDNA (123 bp)
AJ002572.1 Homo sapiens mRNA; transcriptional unit N143

EST sequences (10 of 497) [Show all sequences]

AA984632.1 Clone IMAGE:1629958 brain 3' read
AA985011.1 Clone IMAGE:1577207 spleen 3' read A
AA904905.1 Clone IMAGE:1504492 mixed 3' read P
AA909293.1 Clone IMAGE:1541022 mixed 3' read P
AI004650.1 Clone IMAGE:1626059 mixed 3' read P
AI015091.1 Clone IMAGE:1640875 testis 3' read A
AA948591.1 Clone IMAGE:1560496 mixed 3' read
AI041165.1 Clone IMAGE:1642628 testis 3' read A
R19901.1 Clone IMAGE:34705 brain 5' read
R21497.1 Clone IMAGE:31383 brain 5' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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