> Ankyrin repeat and LEM domain containing 2 (ANKLE2)
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UGID:2723946     UniGene Hs.654628     Homo sapiens (human)   ANKLE2
Ankyrin repeat and LEM domain containing 2 (ANKLE2)

Human protein-coding gene ANKLE2. Represented by 489 ESTs from 226 cDNA libraries. Corresponds to reference sequence NM_015114.1. [UniGene 2723946 - Hs.654628]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_055929.1 ANKLE2 gene product H. sapiens 100.0 937
XP_001152324.2 PREDICTED: ankyrin repeat and LEM domain-containing protein 2 P. troglodytes 99.5 414
NP_082198.1 Ankle2 gene product M. musculus 79.0 962
NP_001119867.1 ankle2 gene product D. rerio 62.1 934
Other hits (2 of 25) [Show all]SpeciesId(%)Len(aa)
XP_003907460.1 PREDICTED: ankyrin repeat and LEM domain-containing protein 2 P. anubis 97.0 938
XP_001087028.1 PREDICTED: ankyrin repeat and LEM domain-containing protein 2-like, partial M. mulatta 96.7 487

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: testis; brain; lung; mouth; eye; stomach; bone marrow; amniotic fluid; adrenal gland; skin; embryonic tissue; intestine; lymph node; kidney; uterus; mixed; uncharacterized tissue; ovary; placenta; prostate; mammary gland; esophagus; trachea; epididymis; bone; liver; thymus; pancreas; muscle; thyroid; blood; adipose tissue; spleen; heart; lymph; bladder; cervix; vascular; ascites; salivary gland; pituitary gland; nerve; connective tissue
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 12
Map position: 12q24.33
UniSTS entry: Chr 12 A005X42
UniSTS entry: Chr 12 G20583
UniSTS entry: Chr 12 RH78044
UniSTS entry: Chr 12 RH44489
UniSTS entry: Chr 12 D12S1638 [Map Viewer]
UniSTS entry: Chr 12 G60570
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (10)

AB014592.1 Homo sapiens mRNA for KIAA0692 protein, partial cds P
BC043157.1 Homo sapiens ankyrin repeat and LEM domain containing 2, mRNA (cDNA clone MGC:44119 IMAGE:5286234), complete cds PA
BC062373.1 Homo sapiens ankyrin repeat and LEM domain containing 2, mRNA (cDNA clone IMAGE:5473979), partial cds PA
BC082962.1 Homo sapiens ankyrin repeat and LEM domain containing 2, mRNA (cDNA clone IMAGE:5473642), partial cds PA
AK024061.1 Homo sapiens cDNA FLJ13999 fis, clone Y79AA1002234, highly similar to Homo sapiens mRNA for KIAA0692 protein P
AK025933.1 Homo sapiens cDNA: FLJ22280 fis, clone HRC03841 PA
NM_015114.1 Homo sapiens ankyrin repeat and LEM domain containing 2 (ANKLE2), mRNA PA
BC001530.2 Homo sapiens ankyrin repeat and LEM domain containing 2, mRNA (cDNA clone IMAGE:3510047), partial cds PA
AK293028.1 Homo sapiens cDNA FLJ77829 complete cds P
BC025347.1 Homo sapiens ankyrin repeat and LEM domain containing 2, mRNA (cDNA clone IMAGE:4891015), partial cds PA

EST sequences (10 of 489) [Show all sequences]

R17855.1 Clone IMAGE:31685 brain 5' read
AA929046.1 Clone IMAGE:1560085 intestine 3' read
AI041117.1 Clone IMAGE:1641846 testis 3' read
AI094081.1 Clone IMAGE:1688503 mixed 3' read A
AI095620.1 Clone IMAGE:1697197 uterus 3' read
AI097053.1 Clone IMAGE:1698448 uterus 3' read A
R22723.1 Clone IMAGE:31642 brain 5' read P
BX114094.1 Clone IMAGp998P10151_;_IMAGE:31642 brain P
AI214572.1 Clone IMAGE:1883180 lung 3' read P
CB159527.1 Clone L18POOL1n1-39-G09 liver 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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