> Receptor-like tyrosine kinase (RYK)
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UGID:2723880     UniGene Hs.654562     Homo sapiens (human)   RYK
Receptor-like tyrosine kinase (RYK)

Human protein-coding gene RYK. Represented by 248 ESTs from 143 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 2723880 - Hs.654562]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001005861.1 RYK gene product H. sapiens 100.0 609
XP_001112355.2 PREDICTED: tyrosine-protein kinase RYK M. mulatta 100.0 476
XP_534269.2 PREDICTED: tyrosine-protein kinase RYK C. lupus familiaris 99.8 529
NP_038677.3 Ryk gene product M. musculus 98.7 592
NP_001089445.1 receptor-like tyrosine kinase precursor X. laevis 91.0 596
NP_001077295.1 ryk gene product D. rerio 89.3 600
NP_477341.2 doughnut on 2, isoform A D. melanogaster 60.8 282
NP_508684.3 abnormal cell LINeage family member (lin-18) C. elegans 54.6 204
Other hits (2 of 35) [Show all]SpeciesId(%)Len(aa)
XP_002685146.2 PREDICTED: tyrosine-protein kinase RYK, partial B. taurus 99.5 577
XP_002716597.1 PREDICTED: RYK receptor-like tyrosine kinase O. cuniculus 99.2 534

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: testis; pancreas; mixed; lung; skin; vascular; liver; kidney; pharynx; brain; uncharacterized tissue; ovary; intestine; eye; prostate; embryonic tissue; uterus; heart; bladder; muscle; cervix; stomach; thyroid; placenta; thymus; mammary gland; connective tissue; blood; bone; lymph node; parathyroid; nerve; ascites; bone marrow
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 3
Map position: 3q22
UniSTS entry: Chr 3 RH81074
UniSTS entry: Chr 3 SHGC-77367 [Map Viewer]
UniSTS entry: Chr 3 WI-12317 [Map Viewer]
UniSTS entry: Chr 3 RH69892
UniSTS entry: Chr 3 RH70882
UniSTS entry: Chr 3 GDB:568595
UniSTS entry: Chr 3 D3S4192
UniSTS entry: Chr 3 D14S567
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (7)

NM_001005861.2 Homo sapiens receptor-like tyrosine kinase (RYK), transcript variant 1, mRNA P
AB209405.1 Homo sapiens mRNA for RYK receptor-like tyrosine kinase isoform 1 variant protein P
NM_002958.3 Homo sapiens receptor-like tyrosine kinase (RYK), transcript variant 2, mRNA P
X96588.1 H.sapiens mRNA for H-RYK receptor tyrosine kinase P
BC021700.2 Homo sapiens RYK receptor-like tyrosine kinase, mRNA (cDNA clone IMAGE:4052080), partial cds PA
X69970.1 H.sapiens mRNA for h-ryk P
S59184.1 RYK=related to receptor tyrosine kinase [human, hepatoma, mRNA, 3068 nt] PA

EST sequences (10 of 248) [Show all sequences]

AA991903.1 Clone IMAGE:1611237 uncharacterized tissue 3' read
R17643.1 Clone IMAGE:32259 brain 5' read
AI125515.1 Clone IMAGE:1736696 testis 3' read A
AI127509.1 Clone IMAGE:1711100 uterus 3' read
AI129463.1 Clone IMAGE:1712457 uterus 3' read A
BX109888.1 Clone IMAGp998M131783_;_IMAGE:727092 testis
CB150029.1 Clone C1SNU17-23-E05 cervix 5' read P
CB140045.1 Clone L9SNU354-4-D06 liver 5' read P
AI279384.1 Clone IMAGE:2006286 ovary 3' read A
AI279386.1 Clone IMAGE:2006290 ovary 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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