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UGID:2723805     UniGene Hs.654487     Homo sapiens (human)   FOLH1
Folate hydrolase (prostate-specific membrane antigen) 1 (FOLH1)

Human protein-coding gene FOLH1. Represented by 155 ESTs from 57 cDNA libraries. EST representation biased toward adult. Corresponds to 5 reference sequences (different isoforms). [UniGene 2723805 - Hs.654487]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_004467.1 FOLH1 gene product H. sapiens 100.0 749
NP_058050.3 Folh1 gene product M. musculus 89.2 751
NP_001089576.1 N-acetylated alpha-linked acidic dipeptidase 2 X. laevis 79.0 709
NP_956571.1 zgc:56429 gene product D. rerio 74.1 730
NP_197475.2 Peptidase M28 family protein A. thaliana 48.3 149
NP_872248.2 Protein R57.1, isoform b C. elegans 45.5 220
Other hits (2 of 35) [Show all]SpeciesId(%)Len(aa)
XP_001137174.1 PREDICTED: glutamate carboxypeptidase 2-like isoform 4 P. troglodytes 99.5 749
XP_001096141.2 PREDICTED: glutamate carboxypeptidase 2-like isoform 1 M. mulatta 98.1 734

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: adult [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; prostate; kidney; mammary gland; salivary gland; liver; mixed; ovary; connective tissue; spleen; mouth; uterus; uncharacterized tissue; muscle; nerve; ganglia; intestine; bone
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 11
Map position: 11p11.2
UniSTS entry: Chr 11 RH71396
UniSTS entry: Chr 11 RH69652
UniSTS entry: Chr 11 RH76660
UniSTS entry: Chr 11 SHGC-81785
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (22)

NM_004476.1 Homo sapiens folate hydrolase (prostate-specific membrane antigen) 1 (FOLH1), transcript variant 1, mRNA PA
AF176574.1 Homo sapiens folylpoly-gamma-glutamate carboxypeptidase (FGCP) mRNA, complete cds PA
AF254357.1 Homo sapiens prostate-specific membrane antigen PSM mRNA, exon 6 alternative splice variant, partial cds P
AF254358.1 Homo sapiens prostate-specific membrane antigen PSM mRNA, exon 18 alternative splice variant, partial cds
NM_001014986.1 Homo sapiens folate hydrolase (prostate-specific membrane antigen) 1 (FOLH1), transcript variant 2, mRNA PA
AB231784.1 Homo sapiens mRNA for hypothetical protein, partial cds, clone:Hsa11-digit35-15-11-R
BC108719.1 Homo sapiens folate hydrolase (prostate-specific membrane antigen) 1, mRNA (cDNA clone IMAGE:6196956), partial cds PA
M99487.1 Human prostate-specific membrane antigen (PSM) mRNA, complete cds PA
EF488812.1 Homo sapiens prostate specific membrane antigen variant F mRNA, complete cds, alternatively spliced P
EF488811.2 Homo sapiens prostate specific membrane antigen variant E mRNA, complete cds, alternatively spliced P
DQ088979.1 Homo sapiens cell growth-inhibiting protein 27 mRNA, complete cds P
AK312366.1 Homo sapiens cDNA, FLJ92688, Homo sapiens folate hydrolase (prostate-specific membrane antigen)1 (FOLH1), mRNA P
BC025672.1 Homo sapiens folate hydrolase (prostate-specific membrane antigen) 1, mRNA (cDNA clone MGC:34488 IMAGE:5202715), complete cds PA
AY101595.1 Homo sapiens prostate-specific membrane antigen mRNA, complete cds P
S76978.1 Homo sapiens prostate-specific membrane antigen (prostate-specific membrane antigen, PSM) mRNA, partial cds
AJ007318.1 Homo sapiens mRNA for prostate-specific membrane antigen, splice variant, partial PA
AK300532.1 Homo sapiens cDNA FLJ57056 partial cds PA
AK295470.1 Homo sapiens cDNA FLJ54681 complete cds PA
AK295368.1 Homo sapiens cDNA FLJ60551 complete cds PA
NM_001193473.1 Homo sapiens folate hydrolase (prostate-specific membrane antigen) 1 (FOLH1), transcript variant 5, mRNA P
NM_001193471.1 Homo sapiens folate hydrolase (prostate-specific membrane antigen) 1 (FOLH1), transcript variant 3, mRNA P
NM_001193472.1 Homo sapiens folate hydrolase (prostate-specific membrane antigen) 1 (FOLH1), transcript variant 4, mRNA P

EST sequences (10 of 155) [Show all sequences]

AI050871.1 Clone IMAGE:1668957 brain 3' read PA
CA976138.1 Clone IMAGE:6202554 nerve 5' read P
AA897668.1 Clone IMAGE:1504426 mixed 3' read P
AI356718.1 Clone IMAGE:2012254 brain 3' read PA
CB215828.1 Clone IMAGE:5937443 uterus 5' read P
CB216928.1 Clone IMAGE:5938635 uterus 5' read P
AI424589.1 Clone IMAGE:2110504 prostate 3' read A
AI474492.1 Clone IMAGE:2118913 prostate 3' read PA
AI478207.1 Clone IMAGE:2161543 kidney 3' read A
AI525228.1 prostate 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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