> ATP-binding cassette, sub-family B (MDR/TAP), member 4 (ABCB4)
NCBI UniGene banner graphic
PubMed Nucleotide Protein Genome Structure Popset Taxonomy
 Search
NCBI

UniGene
Homepage
FAQs
Help
Query Tips
Build Info
Library Browser
DDD
Download UniGene

Related Databases
Gene
HomoloGene
EST
SRA

NIH cDNA Projects
MGC | ZGC | XGC
Finding cDNAs
UGID:2723721     UniGene Hs.654403     Homo sapiens (human)   ABCB4 Order cDNA clone, Links
ATP-binding cassette, sub-family B (MDR/TAP), member 4 (ABCB4)

Human protein-coding gene ABCB4. Represented by 31 ESTs from 23 cDNA libraries. EST representation biased toward blastocyst. Corresponds to 3 reference sequences (different isoforms). [UniGene 2723721 - Hs.654403]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_061337.1 ABCB4 gene product H. sapiens 100.0 1285
XP_003318611.1 PREDICTED: multidrug resistance protein 3 isoform 2 P. troglodytes 99.5 1285
NP_032856.2 Abcb4 gene product M. musculus 90.8 1275
NP_001081394.1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 X. laevis 66.6 1284
XP_001922717.3 PREDICTED: multidrug resistance protein 1 D. rerio 55.6 1284
XP_001692124.1 hypothetical protein CHLREDRAFT_100930 C. reinhardtii 52.2 224
XP_959059.2 hypothetical protein NCU07546 N. crassa 49.1 975
NP_001163132.1 multi drug resistance 49, isoform B D. melanogaster 49.1 1096
NP_191774.2 ABC transporter B family member 21 A. thaliana 47.4 949
NP_507487.1 Protein PGP-9 C. elegans 47.1 1265
NP_015053.2 ATP-binding cassette permease MDL2 S. cerevisiae 45.5 189
Other hits (2 of 65) [Show all]SpeciesId(%)Len(aa)
XP_003896419.1 PREDICTED: multidrug resistance protein 3 isoform 2 P. anubis 98.1 1285
XP_002713880.1 PREDICTED: ATP-binding cassette, subfamily B, member 4 isoform 1 O. cuniculus 92.2 1286

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: blastocyst [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; pancreas; uncharacterized tissue; lymph; blood; intestine; embryonic tissue; mammary gland; muscle; liver; kidney; mixed
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 7
Map position: 7q21.1
UniSTS entry: Chr 7 A006B20
UniSTS entry: Chr 7 RH17678
UniSTS entry: Chr 7 PGY3
UniSTS entry: Chr 7 G20675
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (8)

BC042531.1 Homo sapiens ATP-binding cassette, sub-family B (MDR/TAP), member 4, mRNA (cDNA clone MGC:41801 IMAGE:4837724), complete cds PA
M23234.1 Human membrane glycoprotein P (mdr3) mRNA, complete cds P
NM_000443.3 Homo sapiens ATP-binding cassette, sub-family B (MDR/TAP), member 4 (ABCB4), transcript variant A, mRNA P
NM_018849.2 Homo sapiens ATP-binding cassette, sub-family B (MDR/TAP), member 4 (ABCB4), transcript variant B, mRNA P
NM_018850.2 Homo sapiens ATP-binding cassette, sub-family B (MDR/TAP), member 4 (ABCB4), transcript variant C, mRNA P
BC020618.2 Homo sapiens ATP-binding cassette, sub-family B (MDR/TAP), member 4, mRNA (cDNA clone IMAGE:4767591), complete cds PA
Z35284.1 H.sapiens mRNA for MDR3 P-glycoprotein
X06181.1 Human mRNA 3'-fragment for P-glycoprotein P

EST sequences (10 of 31) [Show all sequences]

T26505.1 Clone LLAB282E2 brain 5' read
R53330.1 Clone IMAGE:39920 brain 5' read
AI708606.1 Clone IMAGE:2333265 intestine 3' read A
AL041030.1 Clone DKFZp434O0915 testis 5' read
AL041031.1 Clone DKFZp434O0915 testis 3' read
BX282642.1 Clone IMAGp998N159955_;_IMAGE:4341710 lymph P
AI922477.1 Clone IMAGE:2454587 pancreas 3' read P
BX392299.1 Clone CS0DC025YG03 uncharacterized tissue 3' read PA
BX325244.1 Clone CS0DJ010YP08 blood 3' read P
BX325245.2 Clone CS0DJ010YP08 blood 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
NLM | NIH | UniGene | Privacy Statement | Disclaimer | NCBI Help