> Myocyte enhancer factor 2C (MEF2C)
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UGID:2480589     UniGene Hs.649965     Homo sapiens (human)   MEF2C Links
Myocyte enhancer factor 2C (MEF2C)

Human protein-coding gene MEF2C. Represented by 588 ESTs from 182 cDNA libraries. EST representation biased toward fetus. Corresponds to 6 reference sequences (different isoforms). [UniGene 2480589 - Hs.649965]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_003899961.1 PREDICTED: myocyte-specific enhancer factor 2C isoform 3 P. anubis 100.0 482
XP_001142588.1 PREDICTED: myocyte-specific enhancer factor 2C isoform 3 P. troglodytes 100.0 482
NP_001180276.1 MEF2C gene product H. sapiens 100.0 482
XP_003362893.1 PREDICTED: myocyte-specific enhancer factor 2C E. caballus 100.0 482
NP_001253376.1 myocyte-specific enhancer factor 2C M. mulatta 100.0 472
XP_849449.1 PREDICTED: myocyte-specific enhancer factor 2C isoform 2 C. lupus familiaris 100.0 472
XP_001056692.2 PREDICTED: myocyte-specific enhancer factor 2C R. norvegicus 99.8 464
NP_001039578.1 MEF2C gene product B. taurus 99.8 440
NP_001038005.1 MEF2C gene product S. scrofa 99.8 432
NP_001152749.1 MEF2C gene product O. aries 99.8 432
XP_002713973.1 PREDICTED: myocyte enhancer factor 2C O. cuniculus 99.5 446
NP_001164008.1 Mef2c gene product M. musculus 99.1 465
NP_492441.1 Protein MEF-2 C. elegans 95.5 110
NP_001085883.1 MADS box transcription enhancer factor 2, polypeptide C (myocyte enhancer factor 2C) X. laevis 95.3 428
NP_571387.2 mef2ca gene product D. rerio 88.0 464
NP_477018.1 myocyte enhancer factor 2, isoform C D. melanogaster 71.4 234
Other hits (2 of 28) [Show all]SpeciesId(%)Len(aa)
XP_001367544.2 PREDICTED: myocyte-specific enhancer factor 2C-like M. domestica 99.4 466
XP_001231662.2 PREDICTED: myocyte-specific enhancer factor 2C G. gallus 99.2 482

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: fetus [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; uncharacterized tissue; mixed; muscle; lymph node; heart; placenta; pancreas; pituitary gland; pharynx; kidney; prostate; skin; liver; embryonic tissue; stomach; blood; testis; bone marrow; spleen; lung; intestine; ovary; esophagus; thymus; trachea; ear; larynx; thyroid; eye; uterus; vascular; mammary gland; connective tissue; adipose tissue; nerve; mouth; parathyroid
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 5
Map position: 5q14
UniSTS entry: Mef2c
UniSTS entry: Chr 5 SGC30054 [Map Viewer]
UniSTS entry: Chr 5 SGC30495 [Map Viewer]
UniSTS entry: Chr 5 MEF2C
UniSTS entry: Mef2c
UniSTS entry: Chr 5 G10647
UniSTS entry: Mef2c
UniSTS entry: Mef2c
UniSTS entry: Chr 5 MEF2C_2028
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (15)

NM_002397.4 Homo sapiens myocyte enhancer factor 2C (MEF2C), transcript variant 1, mRNA P
L08895.1 Homo sapiens MADS/MEF2-family transcription factor (MEF2C) mRNA, complete cds P
AK307883.1 Homo sapiens cDNA, FLJ97831 P
AK312472.1 Homo sapiens cDNA, FLJ92829, highly similar to Homo sapiens MADS box transcription enhancer factor 2, polypeptide C (myocyte enhancer factor 2C) (MEF2C), mRNA P
BC026341.1 Homo sapiens MADS box transcription enhancer factor 2, polypeptide C (myocyte enhancer factor 2C), mRNA (cDNA clone IMAGE:4815933) PA
AL833274.1 Homo sapiens mRNA; cDNA DKFZp451A048 (from clone DKFZp451A048) PA
AL833268.1 Homo sapiens mRNA; cDNA DKFZp451I0810 (from clone DKFZp451I0810) PA
NM_001131005.2 Homo sapiens myocyte enhancer factor 2C (MEF2C), transcript variant 2, mRNA P
S57212.1 hMEF2C=myocyte enhancer-binding factor 2 [human, skeletal muscles, mRNA, 2161 nt] P
FM163484.2 Homo sapiens mRNA for myocyte enhancer factor 2c (MEF2C gene), splice variant VP P
FM180475.1 Homo sapiens mRNA for myocyte enhancer factor 2c (MEF2C gene), splice variant VP2 P
NM_001193350.1 Homo sapiens myocyte enhancer factor 2C (MEF2C), transcript variant 6, mRNA P
NM_001193349.1 Homo sapiens myocyte enhancer factor 2C (MEF2C), transcript variant 5, mRNA P
NM_001193348.1 Homo sapiens myocyte enhancer factor 2C (MEF2C), transcript variant 4, mRNA P
NM_001193347.1 Homo sapiens myocyte enhancer factor 2C (MEF2C), transcript variant 3, mRNA P

EST sequences (10 of 588) [Show all sequences]

AA906395.1 Clone IMAGE:1506450 mixed 3' read
AA970725.1 Clone IMAGE:1573097 kidney 3' read
AA970736.1 Clone IMAGE:1573120 kidney 3' read
AA897616.1 Clone IMAGE:1503798 mixed 3' read
AA928278.1 Clone IMAGE:1562881 mixed 3' read
AI040498.1 Clone IMAGE:1656332 mixed 3' read P
AI052538.1 Clone IMAGE:1676612 embryonic tissue 3' read
AI079291.1 Clone IMAGE:1677095 embryonic tissue 3' read
CA975922.1 Clone IMAGE:6202318 nerve 5' read A
AI124592.1 Clone IMAGE:1539840 brain 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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