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UGID:2477692     UniGene Hs.647068     Homo sapiens (human)   RHEB
Ras homolog enriched in brain (RHEB)

Human protein-coding gene RHEB. Represented by 681 ESTs from 229 cDNA libraries. Corresponds to reference sequence NM_005614.3. [UniGene 2477692 - Hs.647068]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_444305.2 Rheb gene product M. musculus 100.0 183
NP_037348.1 Rheb gene product R. norvegicus 100.0 183
NP_001232539.1 LOC100190126 gene product T. guttata 100.0 183
XP_001104682.1 PREDICTED: GTP-binding protein Rheb-like M. mulatta 100.0 183
XP_003896937.1 PREDICTED: GTP-binding protein Rheb P. anubis 100.0 183
XP_519513.1 PREDICTED: GTP-binding protein Rheb isoform 6 P. troglodytes 100.0 183
NP_005605.1 RHEB gene product H. sapiens 100.0 183
XP_532768.1 PREDICTED: GTP-binding protein Rheb C. lupus familiaris 100.0 183
XP_003134594.1 PREDICTED: GTP-binding protein Rheb-like isoform 1 S. scrofa 100.0 183
NP_001155338.1 RHEB gene product O. aries 100.0 183
XP_002715109.1 PREDICTED: Ras homolog enriched in brain O. cuniculus 100.0 183
XP_003206997.1 PREDICTED: GTP-binding protein Rheb-like M. gallopavo 100.0 168
XP_001232988.2 PREDICTED: GTP-binding protein Rheb isoform 1 G. gallus 100.0 167
NP_957023.1 zgc:73144 gene product D. rerio 95.7 183
NP_001080494.1 Ras homolog enriched in brain X. laevis 94.0 183
NP_730950.2 rheb, isoform A D. melanogaster 71.3 181
XP_955966.1 hypothetical protein NCU01444 N. crassa 57.3 184
NP_499079.1 Protein RHEB-1 C. elegans 46.5 159
Other hits (2 of 36) [Show all]SpeciesId(%)Len(aa)
NP_001026934.1 RHEB gene product B. taurus 99.5 183
XP_001371924.2 PREDICTED: GTP-binding protein Rheb-like M. domestica 99.4 170

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; connective tissue; testis; placenta; lung; uncharacterized tissue; mixed; skin; vascular; uterus; intestine; kidney; prostate; embryonic tissue; liver; ovary; mammary gland; bladder; eye; pancreas; spleen; heart; stomach; muscle; bone marrow; adrenal gland; salivary gland; lymph; ascites; lymph node; thyroid; amniotic fluid; blood; mouth; umbilical cord; cervix; bone; thymus; adipose tissue; esophagus; pineal gland; parathyroid
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 7
Map position: 7q36
UniSTS entry: Chr 7 G62040
UniSTS entry: Chr 7 RH18139
UniSTS entry: Chr 7 RHEB
UniSTS entry: Chr 7 WI-22302 [Map Viewer]
UniSTS entry: Chr 7 SHGC-37157 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (11)

BT006958.1 Homo sapiens Ras homolog enriched in brain 2 mRNA, complete cds P
AK125446.1 Homo sapiens cDNA FLJ43457 fis, clone OCBBF2035226, highly similar to GTP-binding protein Rheb P
AK123729.1 Homo sapiens cDNA FLJ41735 fis, clone HLUNG2018282
NM_005614.3 Homo sapiens Ras homolog enriched in brain (RHEB), mRNA PA
BC066307.1 Homo sapiens Ras homolog enriched in brain, mRNA (cDNA clone MGC:87123 IMAGE:5274556), complete cds PA
BC107705.1 Homo sapiens Ras homolog enriched in brain, mRNA (cDNA clone MGC:111559 IMAGE:6615350), complete cds PA
BC016155.1 Homo sapiens Ras homolog enriched in brain, mRNA (cDNA clone MGC:1391 IMAGE:3528583), complete cds PA
BC009638.1 Homo sapiens Ras homolog enriched in brain, mRNA (cDNA clone IMAGE:3892637), partial cds P
AK289370.1 Homo sapiens cDNA FLJ77896 complete cds, highly similar to Homo sapiens Ras homolog enriched in brain (RHEB), mRNA P
AF493921.1 Homo sapiens Ras family small GTP binding protein RHEB2 (RHEB2) mRNA, complete cds P
Z29677.1 H.sapiens mRNA for ras-related GTP-binding protein P

EST sequences (10 of 681) [Show all sequences]

AA833880.1 Clone IMAGE:1372733 lymph node P
AA903010.1 Clone IMAGE:1516919 uncharacterized tissue 3' read A
AA971428.1 Clone IMAGE:1584327 lung 3' read P
AA976690.1 Clone IMAGE:1585515 lung 3' read P
AA985585.1 Clone IMAGE:1601215 lung 3' read P
AA908686.1 Clone IMAGE:1522510 lung 3' read P
AI039591.1 Clone IMAGE:1664642 skin 3' read PA
AI066794.1 Clone IMAGE:1637582 uncharacterized tissue 3' read
AI081221.1 Clone IMAGE:1662243 mixed 3' read
AI089334.1 Clone IMAGE:1695402 uterus 3' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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