Syntaxin 1A (brain) (STX1A)

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UGID:2477648 UniGene Hs.647024 Homo sapiens (human) STX1A

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Syntaxin 1A (brain) (STX1A)

Human protein-coding gene STX1A. Represented by 339 ESTs from 124 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 2477648 - Hs.647024]

SELECTED PROTEIN SIMILARITIES

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.

Best Hits and Hits from model organisms		Species	Id(%)	Len(aa)
NP_446240.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Stx1a gene product	R. norvegicus	100.0	287
XP_003895927.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: syntaxin-1A	P. anubis	100.0	287
XP_001146754.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: syntaxin-1A isoform 1	P. troglodytes	100.0	287
NP_004594.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	STX1A gene product	H. sapiens	100.0	287
NP_058081.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Stx1a gene product	M. musculus	99.7	287
XP_003124470.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: syntaxin-1A-like	S. scrofa	99.7	287
NP_571598.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	stx1b gene product	D. rerio	87.7	284
NP_524475.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	syntaxin 1A, isoform A	D. melanogaster	76.5	289
NP_001086322.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	syntaxin 3	X. laevis	72.4	285
NP_001022615.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Protein UNC-64, isoform b	C. elegans	70.1	281
Other hits (2 of 36) [Show all]		Species	Id(%)	Len(aa)
NP_001028037.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	STX1A gene product	M. mulatta	99.3	287
XP_003639128.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: syntaxin-1A-like	C. lupus familiaris	99.3	283

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

	EST Profile:	Approximate expression patterns inferred from EST sources. [Show more entries with profiles like this]
	GEO Profiles:	Experimental gene expression data (Gene Expression Omnibus).
	cDNA Sources:	brain; uncharacterized tissue; lung; eye; pancreas; vascular; stomach; testis; connective tissue; ovary; liver; kidney; uterus; thyroid; thymus; adrenal gland; prostate; mouth; ascites; mixed; muscle; bone; pituitary gland; embryonic tissue; esophagus; lymph node; intestine; salivary gland; nerve; bladder; ganglia

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	7
Map position:	7q11.23
UniSTS entry:	Chr 7	D7S2927
UniSTS entry:	Chr 7	RH78389
UniSTS entry:	Chr 7	MARC_14487-14488:1010605685:1
UniSTS entry:	Chr 7	STS-L37792

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (10)

NM_004603.3	Homo sapiens syntaxin 1A (brain) (STX1A), transcript variant 1, mRNA	PA
BC064644.1	Homo sapiens syntaxin 1A (brain), mRNA (cDNA clone MGC:70785 IMAGE:5769528), complete cds	PA
CR457018.1	Homo sapiens full open reading frame cDNA clone RZPDo834H065D for gene STX1A, syntaxin 1A (brain); complete cds, incl. stopcodon	P
L37792.1	Homo sapiens syntaxin 1A mRNA, complete cds	PA
BC003011.1	Homo sapiens syntaxin 1A (brain), mRNA (cDNA clone MGC:4038 IMAGE:2820851), complete cds	PA
BC000444.2	Homo sapiens syntaxin 1A (brain), mRNA (cDNA clone IMAGE:2820851), partial cds	PA
AK313980.1	Homo sapiens cDNA, FLJ94630, Homo sapiens syntaxin 1A (brain) (STX1A), mRNA	P
NM_001165903.1	Homo sapiens syntaxin 1A (brain) (STX1A), transcript variant 2, mRNA	PA
D37932.1	Homo sapiens mRNA for HPC-1, partial cds	PA
U12918.1	Human syntaxin mRNA, complete cds	P

EST sequences (10 of 339) [Show all sequences]

AA972332.1	Clone IMAGE:1582917	mixed	3' read	A
R14620.1	Clone IMAGE:35605	brain	5' read
AA834193.1	Clone IMAGE:1421196	kidney
CB157914.1	Clone L18POOL1n1-5-G03	liver	5' read
CB156684.1	Clone B2N807043-20-D05	brain	5' read	P
CB154483.1	Clone B2N807043-27-C12	brain	5' read	P
CB155238.1	Clone B2N807043-14-A07	brain	5' read	P
T08063.1	Clone HIBAB52	brain	3' read	A
T08064.1	Clone HIBAB52	brain	5' read	P
T08629.1	Clone HIBBH31	brain	5' read	P

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria