Claudin 3 (CLDN3)

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UGID:2477647 UniGene Hs.647023 Homo sapiens (human) CLDN3

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Claudin 3 (CLDN3)

Human protein-coding gene CLDN3. Represented by 475 ESTs from 91 cDNA libraries. Corresponds to reference sequence NM_001306.3. [UniGene 2477647 - Hs.647023]

SELECTED PROTEIN SIMILARITIES

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.

Best Hits and Hits from model organisms		Species	Id(%)	Len(aa)
XP_003318678.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: claudin-3	P. troglodytes	100.0	219
NP_001297.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	CLDN3 gene product	H. sapiens	100.0	219
NP_034032.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Cldn3 gene product	M. musculus	95.4	218
NP_001087400.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	claudin 3	X. laevis	78.4	212
XP_001332015.3 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: claudin-3-like	D. rerio	70.7	231
Other hits (2 of 22) [Show all]		Species	Id(%)	Len(aa)
XP_001112442.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: claudin-3-like	M. mulatta	98.6	219
XP_003895931.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: claudin-3	P. anubis	98.6	219

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

	EST Profile:	Approximate expression patterns inferred from EST sources. [Show more entries with profiles like this]
	GEO Profiles:	Experimental gene expression data (Gene Expression Omnibus).
	cDNA Sources:	intestine; pancreas; mixed; kidney; ovary; prostate; lung; uterus; thyroid; mammary gland; uncharacterized tissue; trachea; cervix; eye; liver; lymph node; stomach; embryonic tissue; parathyroid; heart; ascites; salivary gland; testis; thymus; connective tissue

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	7
Map position:	7q11.23
UniSTS entry:	Chr 7	D7S3297
UniSTS entry:	Chr 7	RH93920
UniSTS entry:	Chr 7	Cldn3
UniSTS entry:	Chr 7	CLDN3_194

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (5)

NM_001306.3	Homo sapiens claudin 3 (CLDN3), mRNA	PA
BC016056.1	Homo sapiens claudin 3, mRNA (cDNA clone MGC:23079 IMAGE:4867858), complete cds	PA
AK313276.1	Homo sapiens cDNA, FLJ93788, Homo sapiens claudin 3 (CLDN3), mRNA	P
BC009083.1	Homo sapiens, claudin 3, clone IMAGE:3855526, mRNA	P
AB000714.1	Homo sapiens hRVP1 mRNA for RVP1, complete cds	P

EST sequences (10 of 475) [Show all sequences]

AA922369.1	Clone IMAGE:1474370	intestine	3' read
AA969490.1	Clone IMAGE:1579554	mixed	3' read
AA970011.1	Clone IMAGE:1581358	mixed	3' read
AA972197.1	Clone IMAGE:1582833	mixed	3' read	P
AA976869.1	Clone IMAGE:1558754	lung	3' read	P
AA983596.1	Clone IMAGE:1559253	intestine	3' read
AA983664.1	Clone IMAGE:1559565	intestine	3' read
AA887460.1	Clone IMAGE:1500874	kidney	3' read	P
AA904601.1	Clone IMAGE:1503830	mixed	3' read
AA923527.1	Clone IMAGE:1536173	kidney	3' read

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria