> Mediator complex subunit 1 (MED1)
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UGID:2224925     UniGene Hs.643754     Homo sapiens (human)   MED1
Mediator complex subunit 1 (MED1)

Human protein-coding gene MED1. Represented by 331 ESTs from 194 cDNA libraries. Corresponds to reference sequence NM_004774.3. [UniGene 2224925 - Hs.643754]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001172406.1 PREDICTED: mediator of RNA polymerase II transcription subunit 1 isoform 6 P. troglodytes 100.0 1580
NP_004765.2 MED1 gene product H. sapiens 100.0 1580
XP_003912976.1 PREDICTED: mediator of RNA polymerase II transcription subunit 1-like, partial P. anubis 99.5 1427
NP_001073587.1 Med1 gene product M. musculus 96.8 1574
NP_001085198.1 mediator of RNA polymerase II transcription subunit 1 X. laevis 79.7 1568
XP_700209.5 PREDICTED: mediator of RNA polymerase II transcription subunit 1 D. rerio 62.7 1547
Other hits (2 of 19) [Show all]SpeciesId(%)Len(aa)
XP_864009.2 PREDICTED: mediator of RNA polymerase II transcription subunit 1 isoform 3 C. lupus familiaris 99.1 1582
XP_002800504.1 PREDICTED: mediator of RNA polymerase II transcription subunit 1-like M. mulatta 99.0 1463

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; uncharacterized tissue; mammary gland; mixed; blood; kidney; pancreas; lung; embryonic tissue; vascular; uterus; pharynx; placenta; testis; lymph node; skin; intestine; liver; larynx; parathyroid; adrenal gland; pituitary gland; mouth; prostate; spleen; thymus; epididymis; thyroid; cervix; lymph; ascites; muscle; connective tissue; esophagus; bone; eye; bone marrow; stomach; heart; ovary
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 17
Map position: 17q12
UniSTS entry: Chr 17 RH12583 [Map Viewer]
UniSTS entry: Chr 17 RH64892 [Map Viewer]
UniSTS entry: Chr 17 RH11014 [Map Viewer]
UniSTS entry: Chr 17 RH79708
UniSTS entry: Chr 17 RH91484
UniSTS entry: Chr 17 RH47206 [Map Viewer]
UniSTS entry: Chr 17 SGC32796 [Map Viewer]
UniSTS entry: Chr 17 SHGC-36242 [Map Viewer]
UniSTS entry: Chr 17 MARC_12057-12058:1004548952:1
UniSTS entry: PPARBP_2041
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (10)

AF055994.1 Homo sapiens thyroid hormone receptor-associated protein complex component TRAP220 mRNA, complete cds P
NM_004774.3 Homo sapiens mediator complex subunit 1 (MED1), mRNA PA
BC060758.1 Homo sapiens mediator complex subunit 1, mRNA (cDNA clone IMAGE:4822636), complete cds PA
AF283812.1 Homo sapiens vitamin D receptor-interacting protein complex component DRIP205 (DRIP205) mRNA, complete cds P
BC131783.1 Homo sapiens mediator complex subunit 1, mRNA (cDNA clone MGC:156289 IMAGE:40125129), complete cds P
AK314185.1 Homo sapiens cDNA, FLJ94908, highly similar to Homo sapiens PPAR binding protein (PPARBP), mRNA P
AK299789.1 Homo sapiens cDNA FLJ50196 partial cds, highly similar to Peroxisome proliferator-activated receptor-binding protein P
BC006517.2 Homo sapiens mediator complex subunit 1, mRNA (cDNA clone IMAGE:3546031), partial cds PA
L40366.1 Homo sapiens thyroid receptor interactor (TRIP2) mRNA, partial cds P
Y13467.1 Homo sapiens mRNA for RB18A protein P

EST sequences (10 of 331) [Show all sequences]

AA970829.1 Clone IMAGE:1560922 mixed 3' read
AA993272.1 Clone IMAGE:1623927 embryonic tissue 3' read
AA923575.1 Clone IMAGE:1527226 mixed 3' read P
AI017966.1 Clone IMAGE:1627784 mixed 3' read
AA909876.1 Clone IMAGE:1523878 mixed 3' read
R19461.1 Clone IMAGE:33696 brain 5' read P
AI040916.1 Clone IMAGE:1647943 parathyroid 3' read
AI051043.1 Clone IMAGE:1649035 parathyroid 3' read A
AI096482.1 Clone IMAGE:1685684 brain 3' read
AI096426.1 Clone IMAGE:1685991 brain 3' read PA


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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