Ras association (RalGDS/AF-6) domain family member 3 (RASSF3)

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UGID:2224776 UniGene Hs.643605 Homo sapiens (human) RASSF3

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Ras association (RalGDS/AF-6) domain family member 3 (RASSF3)

Human protein-coding gene RASSF3. Represented by 101 ESTs from 59 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 2224776 - Hs.643605]

SELECTED PROTEIN SIMILARITIES

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.

Best Hits and Hits from model organisms		Species	Id(%)	Len(aa)
NP_835463.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	RASSF3 gene product	H. sapiens	100.0	237
XP_003313675.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: ras association domain-containing protein 3-like, partial	P. troglodytes	100.0	221
NP_620406.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Rassf3 gene product	M. musculus	93.5	231
NP_001085497.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Ras association (RalGDS/AF-6) domain family member 3	X. laevis	69.1	243
XP_001331813.3 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: ras association domain-containing protein 5-like isoform 1	D. rerio	59.3	241
Other hits (2 of 19) [Show all]		Species	Id(%)	Len(aa)
XP_001105517.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: ras association domain-containing protein 3-like	M. mulatta	98.2	167
XP_003906773.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: ras association domain-containing protein 3	P. anubis	98.2	167

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

	EST Profile:	Approximate expression patterns inferred from EST sources. [Show more entries with profiles like this]
	GEO Profiles:	Experimental gene expression data (Gene Expression Omnibus).
	cDNA Sources:	prostate; mixed; uncharacterized tissue; ear; intestine; stomach; uterus; lung; skin; embryonic tissue; ovary; vascular; placenta; mammary gland; thyroid; liver; blood; testis; connective tissue; brain; spleen; lymph node; adipose tissue

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	12
Map position:	12q14.2
UniSTS entry:	Chr 12	RH102266

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (7)

AY217662.1	Homo sapiens putative RAS binding protein isoform A (RASSF5) mRNA, complete cds; alternatively spliced	P
NM_178169.3	Homo sapiens Ras association (RalGDS/AF-6) domain family member 3 (RASSF3), transcript variant 1, mRNA	P
BC100951.1	Homo sapiens Ras association (RalGDS/AF-6) domain family member 3, mRNA (cDNA clone MGC:119196 IMAGE:40004481), complete cds	P
BC100950.1	Homo sapiens Ras association (RalGDS/AF-6) domain family member 3, mRNA (cDNA clone MGC:119195 IMAGE:40004478), complete cds	P
BC100952.1	Homo sapiens Ras association (RalGDS/AF-6) domain family member 3, mRNA (cDNA clone MGC:119197 IMAGE:40004484), complete cds	P
BC100949.2	Homo sapiens Ras association (RalGDS/AF-6) domain family member 3, mRNA (cDNA clone MGC:119194 IMAGE:40004477), complete cds	P
NR_040718.1	Homo sapiens Ras association (RalGDS/AF-6) domain family member 3 (RASSF3), transcript variant 2, non-coding RNA	P

EST sequences (10 of 101) [Show all sequences]

AA969174.1	Clone IMAGE:1580301	mixed	3' read
AA974613.1	Clone IMAGE:1578772	mixed	3' read	A
AI092770.1	Clone IMAGE:1688801	mixed	3' read
AI128033.1	Clone IMAGE:1712321	uterus	3' read	A
AI219771.1	Clone IMAGE:1837685	testis	3' read
AI204040.1	Clone IMAGE:1745025	lung	3' read
CB159977.1	Clone L18POOL1n1-45-C09	liver	5' read
AA904881.1	Clone IMAGE:1504125	mixed	3' read
AA928391.1	Clone IMAGE:1553157	uncharacterized tissue	3' read
AI242679.1	Clone IMAGE:1856846	mixed	3' read	A

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria