> SET domain, bifurcated 1 (SETDB1)
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UGID:2224736     UniGene Hs.643565     Homo sapiens (human)   SETDB1 Order cDNA clone, Links
SET domain, bifurcated 1 (SETDB1)

Human protein-coding gene SETDB1. Represented by 392 ESTs from 196 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 2224736 - Hs.643565]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001138887.1 SETDB1 gene product H. sapiens 100.0 1290
XP_524864.3 PREDICTED: histone-lysine N-methyltransferase SETDB1 isoform 2 P. troglodytes 99.9 1290
XP_003892658.1 PREDICTED: histone-lysine N-methyltransferase SETDB1 P. anubis 99.9 1189
XP_001106711.2 PREDICTED: histone-lysine N-methyltransferase SETDB1 M. mulatta 99.8 1289
NP_001157114.1 Setdb1 gene product M. musculus 96.8 1306
NP_001085076.2 histone-lysine N-methyltransferase SETDB1 X. laevis 82.7 1274
NP_001070745.2 setdb1b gene product D. rerio 76.8 1200
NP_611966.3 eggless D. melanogaster 56.8 362
Other hits (2 of 33) [Show all]SpeciesId(%)Len(aa)
XP_001490962.3 PREDICTED: histone-lysine N-methyltransferase SETDB1 E. caballus 99.0 1297
XP_540304.3 PREDICTED: histone-lysine N-methyltransferase SETDB1 C. lupus familiaris 98.7 1292

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; muscle; uncharacterized tissue; uterus; lung; kidney; eye; mouth; thymus; skin; prostate; intestine; adipose tissue; liver; mixed; lymph node; placenta; embryonic tissue; mammary gland; thyroid; ovary; heart; blood; bone marrow; esophagus; trachea; spleen; bladder; epididymis; tonsil; ascites; connective tissue; bone; pancreas; cervix; stomach; ear; lymph; salivary gland; ganglia
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 1
Map position: 1q21
UniSTS entry: Chr 1 SHGC-2406 [Map Viewer]
UniSTS entry: Chr 1 D1S3444
UniSTS entry: Chr 1 RH68265 [Map Viewer]
UniSTS entry: Chr 1 Cda0kh05 [Map Viewer]
UniSTS entry: Chr 1 RH12118 [Map Viewer]
UniSTS entry: Chr 1 D1S2372 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (7)

NM_012432.3 Homo sapiens SET domain, bifurcated 1 (SETDB1), transcript variant 2, mRNA P
BC009362.2 Homo sapiens SET domain, bifurcated 1, mRNA (cDNA clone IMAGE:4301680), complete cds PA
AK308335.1 Homo sapiens cDNA, FLJ98283 P
BC028671.2 Homo sapiens SET domain, bifurcated 1, mRNA (cDNA clone MGC:16563 IMAGE:4098658), complete cds PA
NM_001145415.1 Homo sapiens SET domain, bifurcated 1 (SETDB1), transcript variant 1, mRNA P
D31891.1 Homo sapiens KIAA0067 mRNA, partial cds P
NM_001243491.1 Homo sapiens SET domain, bifurcated 1 (SETDB1), transcript variant 3, mRNA PA

EST sequences (10 of 392) [Show all sequences]

AI002647.1 Clone IMAGE:1629144 mixed 3' read
AI017911.1 Clone IMAGE:1629052 mixed 3' read P
AI026787.1 Clone IMAGE:1645285 testis 3' read
AI052386.1 Clone IMAGE:1676180 embryonic tissue 3' read PA
CB045553.1 Clone IMAGE:3218230 intestine 5' read P
CB047346.1 Clone IMAGE:3253241 kidney 5' read
AI160504.1 Clone IMAGE:1716132 placenta 3' read PA
BX117756.1 Clone IMAGp998K19138_;_IMAGE:25755 brain A
CB155911.1 Clone L17N670205n1-1-B04 liver 5' read
CB153628.1 Clone B1T694954-33-H03 brain 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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