> Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide (YWHAB)
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UGID:2224715     UniGene Hs.643544     Homo sapiens (human)   YWHAB Order cDNA clone, Links
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide (YWHAB)

Human protein-coding gene YWHAB. Represented by 2189 ESTs from 604 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 2224715 - Hs.643544]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_061223.2 Ywhab gene product M. musculus 100.0 245
NP_062250.1 Ywhab gene product R. norvegicus 100.0 245
XP_001109676.2 PREDICTED: 14-3-3 protein beta/alpha M. mulatta 100.0 245
XP_003904746.1 PREDICTED: 14-3-3 protein beta/alpha isoform 1 P. anubis 100.0 245
XP_003317000.1 PREDICTED: 14-3-3 protein beta/alpha isoform 1 P. troglodytes 100.0 245
NP_647539.1 YWHAB gene product H. sapiens 100.0 245
XP_001503158.1 PREDICTED: 14-3-3 protein beta/alpha-like E. caballus 100.0 245
XP_001927289.1 PREDICTED: 14-3-3 protein beta/alpha isoform 1 S. scrofa 100.0 245
NP_777219.2 YWHAB gene product B. taurus 100.0 245
XP_004014639.1 PREDICTED: 14-3-3 protein beta/alpha O. aries 100.0 245
XP_002721273.1 PREDICTED: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide-like O. cuniculus 100.0 245
XP_001518806.2 PREDICTED: 14-3-3 protein beta/alpha-like O. anatinus 100.0 243
XP_852754.1 PREDICTED: 14-3-3 protein beta/alpha isoform 2 C. lupus familiaris 100.0 243
XP_001369909.1 PREDICTED: 14-3-3 protein beta/alpha-like M. domestica 99.6 245
NP_001076267.1 ywhaba gene product D. rerio 94.3 243
NP_001165524.1 14-3-3-like protein X. laevis 91.8 243
NP_509939.1 Protein FTT-2, isoform a C. elegans 84.3 247
NP_476885.2 14-3-3zeta, isoform D D. melanogaster 82.1 245
NP_011104.3 Bmh1p S. cerevisiae 70.0 263
XP_001702812.1 14-3-3 protein C. reinhardtii 69.4 252
NP_564451.2 general regulatory factor 11 A. thaliana 68.9 254
XP_964462.1 14-3-3 protein 7 N. crassa 68.3 259
Other hits (2 of 55) [Show all]SpeciesId(%)Len(aa)
NP_001006289.1 YWHAB gene product G. gallus 99.2 243
XP_003212008.1 PREDICTED: 14-3-3 protein beta/alpha-like M. gallopavo 99.2 243

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; skin; testis; lung; mixed; intestine; pancreas; mammary gland; placenta; uncharacterized tissue; prostate; uterus; liver; embryonic tissue; eye; kidney; ovary; blood; lymph node; stomach; bone; heart; thymus; spleen; connective tissue; thyroid; ascites; bladder; bone marrow; adrenal gland; tonsil; muscle; vascular; cervix; ear; salivary gland; parathyroid; lymph; pharynx; mouth; adipose tissue; nerve; larynx; ganglia; umbilical cord; pineal gland; esophagus; trachea; pituitary gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 20
Map position: 20q13.1
UniSTS entry: Chr 20 STS-N23075 [Map Viewer]
UniSTS entry: Chr 20 STS-X57346 [Map Viewer]
UniSTS entry: Chr 20 D20S586E [Map Viewer]
UniSTS entry: Chr 20 D20S556E
UniSTS entry: Chr 20 D20S528E
UniSTS entry: Chr 11 SHGC-37252
UniSTS entry: RH66089
UniSTS entry: Chr 11 YWHAB__v346
UniSTS entry: Chr 20 Z94504
UniSTS entry: Chr 1 D10S16
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (12)

NM_003404.3 Homo sapiens tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide (YWHAB), transcript variant 1, mRNA P
AF107406.1 Homo sapiens GW128 mRNA, complete cds A
AB209759.1 Homo sapiens mRNA for tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide variant protein P
BC001359.2 Homo sapiens tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide, mRNA (cDNA clone MGC:1580 IMAGE:3051079), complete cds PA
BC010352.1 Homo sapiens tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide, mRNA (cDNA clone IMAGE:4292790) A
AK292717.1 Homo sapiens cDNA FLJ75977 complete cds, highly similar to Homo sapiens tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide (YWHAB), transcript variant 1, mRNA P
X57346.1 H.sapiens mRNA for HS1 protein PA
NM_139323.2 Homo sapiens tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide (YWHAB), transcript variant 2, mRNA P
AL834170.1 Homo sapiens mRNA; cDNA DKFZp762B1113 (from clone DKFZp762B1113) P
AB451386.1 Homo sapiens YWHAB mRNA for 14-3-3 protein beta/alpha, partial cds, clone: FLJ08074AAAF P
AB451260.1 Homo sapiens YWHAB mRNA for 14-3-3 protein beta/alpha, complete cds, clone: FLJ08074AAAN P
AF064847.1 Homo sapiens map 20q13.3; 51cR from D20S173 repeat region, complete sequence P

EST sequences (10 of 2189) [Show all sequences]

AA962407.1 Clone IMAGE:1569989 lung 3' read
AA985151.1 Clone IMAGE:1616302 brain 3' read
AA992113.1 Clone IMAGE:1622052 embryonic tissue 3' read A
AA834089.1 Clone IMAGE:1422246 kidney P
AA927865.1 Clone IMAGE:1541370 mixed 3' read A
AI023104.1 Clone IMAGE:1650528 parathyroid 3' read A
AI023176.1 Clone IMAGE:1651802 skin 3' read
AI022053.1 Clone IMAGE:1652365 mixed 3' read
AI025877.1 Clone IMAGE:1646634 parathyroid 3' read
AI026008.1 Clone IMAGE:1645729 parathyroid 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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