> DiGeorge syndrome critical region gene 8 (DGCR8)
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UGID:2224623     UniGene Hs.643452     Homo sapiens (human)   DGCR8 Order cDNA clone, Links
DiGeorge syndrome critical region gene 8 (DGCR8)

Human protein-coding gene DGCR8. Represented by 295 ESTs from 131 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 2224623 - Hs.643452]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_003905282.1 PREDICTED: microprocessor complex subunit DGCR8 isoform 1 P. anubis 100.0 772
XP_003953874.1 PREDICTED: microprocessor complex subunit DGCR8 isoform 1 P. troglodytes 100.0 772
NP_073557.3 DGCR8 gene product H. sapiens 100.0 772
XP_002798320.1 PREDICTED: microprocessor complex subunit DGCR8-like isoform 1 M. mulatta 99.9 772
NP_201581.2 Dgcr8 gene product M. musculus 98.2 772
NP_001085043.1 uncharacterized protein LOC432110 X. laevis 87.3 771
NP_001116221.1 microprocessor complex subunit DGCR8 D. rerio 85.3 781
NP_651879.1 partner of drosha, isoform A D. melanogaster 49.1 285
Other hits (2 of 28) [Show all]SpeciesId(%)Len(aa)
XP_543542.4 PREDICTED: microprocessor complex subunit DGCR8 C. lupus familiaris 98.7 772
XP_001488087.1 PREDICTED: microprocessor complex subunit DGCR8-like isoform 1 E. caballus 98.3 772

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: uncharacterized tissue; brain; testis; kidney; prostate; embryonic tissue; lymph node; stomach; mixed; thymus; bone marrow; ovary; amniotic fluid; muscle; blood; thyroid; mouth; cervix; skin; pancreas; lung; liver; uterus; eye; placenta; intestine; adipose tissue; esophagus; connective tissue; mammary gland; bone; spleen
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 22
Map position: 22q11.2
UniSTS entry: Chr 22 RH76352
UniSTS entry: Chr 22 G43633
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (13)

AY189282.1 Homo sapiens LP4941 protein mRNA, complete cds PA
CR456356.1 Homo sapiens Em:AC006547.4 full length open reading frame (ORF) cDNA clone (cDNA clone C22ORF:pGEM.Em:AC006547.4.V3) P
BC078147.1 Homo sapiens DiGeorge syndrome critical region gene 8, mRNA (cDNA clone MGC:87832 IMAGE:6014346), complete cds PA
AK222796.1 Homo sapiens mRNA for DiGeorge syndrome critical region gene 8 variant, clone: HEP03022 P
AK025427.1 Homo sapiens cDNA: FLJ21774 fis, clone COLF7927 A
AK025539.1 Homo sapiens cDNA: FLJ21886 fis, clone HEP03022 PA
AK025780.1 Homo sapiens cDNA: FLJ22127 fis, clone HEP19530 PA
NM_022720.6 Homo sapiens DiGeorge syndrome critical region gene 8 (DGCR8), transcript variant 1, mRNA PA
BC009323.2 Homo sapiens DiGeorge syndrome critical region gene 8, mRNA (cDNA clone IMAGE:4123948), partial cds PA
BC009984.2 Homo sapiens DiGeorge syndrome critical region gene 8, mRNA (cDNA clone IMAGE:4125284), complete cds PA
AK313357.1 Homo sapiens cDNA, FLJ93883, Homo sapiens DiGeorge syndrome critical region gene 8 (DGCR8), mRNA P
BC037564.1 Homo sapiens DiGeorge syndrome critical region gene 8, mRNA (cDNA clone IMAGE:4522303) PA
NM_001190326.1 Homo sapiens DiGeorge syndrome critical region gene 8 (DGCR8), transcript variant 2, mRNA P

EST sequences (10 of 295) [Show all sequences]

AI028241.1 Clone IMAGE:1645517 testis 3' read
AI093736.1 Clone IMAGE:1688122 mixed 3' read P
T06489.1 Clone HFBDU18 brain
BX103512.1 Clone IMAGp998L1678_;_IMAGE:66975 mixed P
AI269257.1 Clone IMAGE:1865189 kidney 3' read P
CB116125.1 Clone L10ChoCK0-7-H04 liver 5' read P
CB129878.1 Clone L15CKK1-2-G10 liver 5' read P
AI241247.1 Clone IMAGE:1868173 kidney 3' read A
AI283081.1 Clone IMAGE:1892280 placenta 3' read A
AI291279.1 Clone IMAGE:1882017 lung 3' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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