> ADAM metallopeptidase with thrombospondin type 1 motif, 1 (ADAMTS1)
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UGID:2224534     UniGene Hs.643357     Homo sapiens (human)   ADAMTS1 Order cDNA clone, Links
ADAM metallopeptidase with thrombospondin type 1 motif, 1 (ADAMTS1)

Human protein-coding gene ADAMTS1. Represented by 532 ESTs from 197 cDNA libraries. Corresponds to reference sequence NM_006988.3. [UniGene 2224534 - Hs.643357]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_531406.2 PREDICTED: A disintegrin and metalloproteinase with thrombospondin motifs 1 P. troglodytes 100.0 966
NP_008919.3 ADAMTS1 gene product H. sapiens 100.0 966
XP_001103864.1 PREDICTED: a disintegrin and metalloproteinase with thrombospondin motifs 1 M. mulatta 99.7 966
XP_003895629.1 PREDICTED: A disintegrin and metalloproteinase with thrombospondin motifs 1 P. anubis 99.7 966
NP_033751.3 Adamts1 gene product M. musculus 89.8 967
NP_001088627.1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 precursor X. laevis 82.5 921
XP_693535.5 PREDICTED: A disintegrin and metalloproteinase with thrombospondin motifs 1 D. rerio 70.4 912
NP_501792.2 abnormal GONad development family member (gon-1) C. elegans 51.8 487
NP_001162678.1 CG4096, isoform C D. melanogaster 47.0 360
Other hits (2 of 33) [Show all]SpeciesId(%)Len(aa)
XP_001496538.1 PREDICTED: A disintegrin and metalloproteinase with thrombospondin motifs 1 E. caballus 97.0 724
NP_001138315.1 A disintegrin and metalloproteinase with thrombospondin motifs 1 precursor S. scrofa 93.7 946

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: uterus; prostate; brain; placenta; connective tissue; uncharacterized tissue; mixed; lung; pancreas; heart; skin; larynx; embryonic tissue; thyroid; muscle; testis; trachea; esophagus; liver; thymus; nerve; bladder; eye; kidney; adrenal gland; intestine; amniotic fluid; vascular; ovary; bone; mammary gland; stomach; ear; cervix; ganglia; parathyroid; adipose tissue; bone marrow
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 21
Map position: 21q21.2
UniSTS entry: Chr 21 A005R14
UniSTS entry: Chr 21 G32278
UniSTS entry: Chr 21 D21S1964
UniSTS entry: Chr 21 STS-R76276
UniSTS entry: Chr 21 D21S2033 [Map Viewer]
UniSTS entry: Chr 21 SHGC-51859
UniSTS entry: Chr 21 MARC_10651-10652:1000474642:1
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (13)

BX647388.1 Homo sapiens mRNA; cDNA DKFZp686E01144 (from clone DKFZp686E01144) PA
AK129873.1 Homo sapiens cDNA FLJ26363 fis, clone HRT05360, highly similar to ADAM-TS 1 PRECURSOR (EC 3.4.24.-) P
NM_006988.3 Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif, 1 (ADAMTS1), mRNA PA
AB037767.1 Homo sapiens mRNA for KIAA1346 protein, partial cds P
AL162080.1 Homo sapiens mRNA; cDNA DKFZp762C1110 (from clone DKFZp762C1110); partial cds PA
AF060152.1 Homo sapiens METH1 protein (METH1) mRNA, complete cds PA
AF170084.1 Homo sapiens metalloproteinase with thrombospondin type 1 motifs ADAMTS1 (ADAMTS1) mRNA, complete cds PA
AF207664.1 Homo sapiens matrix metalloprotease (ADAMTS1) mRNA, complete cds PA
DQ108407.1 Homo sapiens ADAMTS1 (ADAMTS1) mRNA, partial cds
AK314475.1 Homo sapiens cDNA, FLJ95281, highly similar to Homo sapiens a disintegrin-like and metalloprotease (reprolysintype) with thrombospondin type 1 motif, 1 (ADAMTS1), mRNA P
BC036515.2 Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif, 1, mRNA (cDNA clone MGC:32979 IMAGE:5266513), complete cds PA
AL355724.1 Homo sapiens EST from clone 324818, 5' end
AL355723.1 Homo sapiens EST from clone 262014, 5' end

EST sequences (10 of 532) [Show all sequences]

AA903074.1 Clone IMAGE:1516985 uncharacterized tissue 3' read A
AA987460.1 Clone IMAGE:1601622 lung 3' read A
AA993528.1 Clone IMAGE:1623137 embryonic tissue 3' read A
AA834490.1 Clone IMAGE:1421740 kidney
AA904875.1 Clone IMAGE:1504113 mixed 3' read A
AI027793.1 Clone IMAGE:1646239 parathyroid 3' read
AI040586.1 Clone IMAGE:1656394 mixed 3' read A
R19976.1 Clone IMAGE:34684 brain 5' read
R20636.1 Clone IMAGE:26404 brain 3' read A
R20667.1 Clone IMAGE:26419 brain 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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