> Insulin-like growth factor binding protein 1 (IGFBP1)
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UGID:2224145     UniGene Hs.642938     Homo sapiens (human)   IGFBP1
Insulin-like growth factor binding protein 1 (IGFBP1)

Human protein-coding gene IGFBP1. Represented by 815 ESTs from 41 cDNA libraries. EST representation biased toward placenta; adult. Corresponds to reference sequence NM_000596.2. [UniGene 2224145 - Hs.642938]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_000587.1 IGFBP1 gene product H. sapiens 100.0 258
NP_032367.3 Igfbp1 gene product M. musculus 75.0 271
NP_001083237.1 insulin-like growth factor binding protein 1 precursor X. laevis 48.1 258
Other hits (2 of 16) [Show all]SpeciesId(%)Len(aa)
XP_519083.3 PREDICTED: insulin-like growth factor binding protein 1 P. troglodytes 99.3 280
XP_003896058.1 PREDICTED: insulin-like growth factor-binding protein 1 P. anubis 95.0 282

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: placenta [show more like this]
adult [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: placenta; liver; uterus; mixed; brain; blood; uncharacterized tissue; skin; spleen; lung; pancreas; bone; embryonic tissue
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 7
Map position: 7p13-p12
UniSTS entry: Chr 7 G54036
UniSTS entry: Chr 7 RH17691 [Map Viewer]
UniSTS entry: Chr 7 G15906
UniSTS entry: Chr 7 SHGC-12673 [Map Viewer]
UniSTS entry: Chr 7 SGC33000 [Map Viewer]
UniSTS entry: Chr 7 G67139
UniSTS entry: Chr 7 G67143
UniSTS entry: Chr 7 G67141
UniSTS entry: Chr 7 G67142
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (13)

BC057806.1 Homo sapiens insulin-like growth factor binding protein 1, mRNA (cDNA clone MGC:71720 IMAGE:30337849), complete cds PA
NM_000596.2 Homo sapiens insulin-like growth factor binding protein 1 (IGFBP1), mRNA PA
M20841.1 Human insulin-like growth factor (IGF) binding protein mRNA, complete cds P
M31145.1 Human insulin-like growth factor binding protein mRNA, complete cds P
BT019685.1 Homo sapiens insulin-like growth factor binding protein 1 mRNA, complete cds P
Y00856.1 Human mRNA for insulin-like growth factor binding protein IBP-1 (IGF-binding protein) P
X13405.1 Human mRNA for insulin-like growth factor-binding protein/placental protein 12 P
X12385.1 Human mRNA for placental protein (PP12) P
AK314925.1 Homo sapiens cDNA, FLJ95834, Homo sapiens insulin-like growth factor binding protein 1 (IGFBP1),mRNA P
AF042356.1 Homo sapiens insulin-like growth factor binding protein (IGFBP1) mRNA, 3' untranslated region, partial sequence A
X15002.1 Human mRNA for small insulin-like growth-factor-binding protein P
FJ795026.1 Homo sapiens insulin-like growth factor binding protein 1 precursor (IGFBP1) mRNA, partial cds P
BC035263.1 Homo sapiens insulin-like growth factor binding protein 1, mRNA (cDNA clone MGC:30041 IMAGE:4800940), complete cds PA

EST sequences (10 of 815) [Show all sequences]

AI078193.1 Clone IMAGE:1675152 mixed 3' read A
AI088409.1 Clone IMAGE:1696496 uterus 3' read A
AI089402.1 Clone IMAGE:1695809 uterus 3' read A
AI092546.1 Clone IMAGE:1689087 mixed 3' read A
AI093547.1 Clone IMAGE:1695711 uterus 3' read A
AI095848.1 Clone IMAGE:1697394 uterus 3' read A
AI095925.1 Clone IMAGE:1696911 uterus 3' read A
AI126001.1 Clone IMAGE:1713064 uterus 3' read A
AI128347.1 Clone IMAGE:1714650 placenta 3' read A
AI151435.1 Clone IMAGE:1721332 uterus 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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