> ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 (ATP6V1B1)
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UGID:139043     UniGene Hs.64173     Homo sapiens (human)   ATP6V1B1
ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 (ATP6V1B1)

Human protein-coding gene ATP6V1B1. Represented by 140 ESTs from 49 cDNA libraries. EST representation biased toward adult. Corresponds to reference sequence NM_001692.3. [UniGene 139043 - Hs.64173]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_003908841.1 PREDICTED: V-type proton ATPase subunit B, kidney isoform P. anubis 100.0 512
NP_001683.2 ATP6V1B1 gene product H. sapiens 100.0 512
XP_001100824.1 PREDICTED: v-type proton ATPase subunit B, kidney isoform-like isoform 3 M. mulatta 99.8 512
XP_001145161.1 PREDICTED: V-type proton ATPase subunit B, kidney isoform isoform 3 P. troglodytes 99.6 512
NP_598918.1 Atp6v1b1 gene product M. musculus 96.3 512
NP_476908.1 vacuolar H[+]-ATPase 55kD B subunit, isoform B D. melanogaster 91.7 484
NP_001090361.1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 X. laevis 91.7 495
NP_878298.1 atp6v1ba gene product D. rerio 91.2 500
NP_508711.1 Protein VHA-12 C. elegans 89.5 477
NP_177729.1 V-type proton ATPase subunit B1 A. thaliana 85.6 465
XP_963165.1 vacuolar ATP synthase subunit B N. crassa 83.3 480
NP_009685.3 Vma2p S. cerevisiae 83.3 474
XP_001701846.1 vacuolar ATP synthase subunit B C. reinhardtii 82.1 491
Other hits (2 of 62) [Show all]SpeciesId(%)Len(aa)
XP_004006102.1 PREDICTED: V-type proton ATPase subunit B, kidney isoform O. aries 97.1 512
NP_788827.1 ATP6V1B1 gene product B. taurus 96.9 512

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: adult [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: kidney; placenta; mammary gland; ovary; mixed; lung; eye; uterus; testis; salivary gland; brain; uncharacterized tissue; trachea
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 2
Map position: 2p13.1
UniSTS entry: Atp6v1b1
UniSTS entry: Chr 2 STS-AA019900
UniSTS entry: Chr 2 SHGC-14337
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (7)

M25809.1 Human endomembrane proton pump subunit mRNA, complete cds P
NM_001692.3 Homo sapiens ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 (ATP6V1B1), mRNA PA
BC063411.1 Homo sapiens ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1, mRNA (cDNA clone MGC:74733 IMAGE:5208385), complete cds PA
AK223151.1 Homo sapiens mRNA for ATPase, H+ transporting, lysosomal 56/58kD, V1 subunit B, isoform 1 variant, clone: KDN09647 P
AK291121.1 Homo sapiens cDNA FLJ76815 complete cds, highly similar to Homo sapiens ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B, isoform 1 (Renal tubular acidosis with deafness) (ATP6V1B1), mRNA P
AK313194.1 Homo sapiens cDNA, FLJ93693, Homo sapiens ATPase, H+ transporting, lysosomal 56/58kDa, V1subunit B, isoform 1 (Renal tubular acidosis with deafness)(ATP6V1B1), mRNA P
AK301542.1 Homo sapiens cDNA FLJ57632 complete cds, highly similar to Vacuolar ATP synthase subunit B, kidney isoform (EC 3.6.3.14) PA

EST sequences (10 of 140) [Show all sequences]

BX097409.1 Clone IMAGp998B20247_;_IMAGE:156211 mammary gland P
AI168259.1 Clone IMAGE:1565759 mixed 3' read A
AI262585.1 Clone IMAGE:1869757 kidney 3' read A
AI364391.1 Clone IMAGE:1993225 uterus 3' read
AI471643.1 Clone IMAGE:2136969 kidney 3' read A
AI498696.1 Clone IMAGE:2160782 kidney 3' read A
AI627730.1 Clone IMAGE:2279526 uterus 3' read P
AI668571.1 Clone IMAGE:156211 mammary gland 3' read
CB250555.1 Clone UI-CF-FN0-agd-a-22-0-UI lung 3' read PA
CB250605.1 Clone UI-CF-FN0-agd-k-22-0-UI lung 3' read PA


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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