> DENN/MADD domain containing 2A (DENND2A)
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UGID:131856     UniGene Hs.6385     Homo sapiens (human)   DENND2A Order cDNA clone, Links
DENN/MADD domain containing 2A (DENND2A)

Human protein-coding gene DENND2A. Represented by 115 ESTs from 79 cDNA libraries. Corresponds to reference sequence NM_015689.3. [UniGene 131856 - Hs.6385]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_056504.3 DENND2A gene product H. sapiens 100.0 1008
XP_001154040.2 PREDICTED: DENN domain-containing protein 2A isoform 2 P. troglodytes 99.9 1008
NP_766065.1 Dennd2a gene product M. musculus 91.8 998
XP_001920375.3 PREDICTED: DENN domain-containing protein 2A D. rerio 79.3 679
NP_001086599.1 DENN/MADD domain containing 2D X. laevis 58.2 423
Other hits (2 of 21) [Show all]SpeciesId(%)Len(aa)
XP_003896731.1 PREDICTED: DENN domain-containing protein 2A P. anubis 98.8 971
XP_002808413.1 PREDICTED: LOW QUALITY PROTEIN: DENN domain-containing protein 2A-like M. mulatta 96.1 1078

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; mixed; uterus; embryonic tissue; mammary gland; eye; kidney; uncharacterized tissue; testis; lung; heart; pituitary gland; placenta; trachea; skin; prostate; spleen; muscle; salivary gland; liver; bone; ovary; stomach; adrenal gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 7
Map position: 7q34
UniSTS entry: Chr 7 STS-W87388
UniSTS entry: Chr 7 IB3120 [Map Viewer]
UniSTS entry: Chr 1 D10S275
UniSTS entry: Chr 1 D1S1425
UniSTS entry: Chr 1 D11S2921
UniSTS entry: Chr 1 D10S16
UniSTS entry: Chr 1 D8S2279
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (8)

BC049193.1 Homo sapiens DENN/MADD domain containing 2A, mRNA (cDNA clone IMAGE:4445131), partial cds PA
AB033103.2 Homo sapiens mRNA for KIAA1277 protein, partial cds P
NM_015689.3 Homo sapiens DENN/MADD domain containing 2A (DENND2A), mRNA PA
BC115004.1 Homo sapiens DENN/MADD domain containing 2A, mRNA (cDNA clone MGC:131568 IMAGE:7470138), complete cds PA
BC132875.1 Homo sapiens DENN/MADD domain containing 2A, mRNA (cDNA clone MGC:164506 IMAGE:40146897), complete cds P
AK290056.1 Homo sapiens cDNA FLJ76768 complete cds P
AK297959.1 Homo sapiens cDNA FLJ54496 complete cds, highly similar to DENN domain-containing protein 2A P
BC144190.1 Homo sapiens cDNA clone IMAGE:9052710, containing frame-shift errors P

EST sequences (10 of 115) [Show all sequences]

AI003965.1 Clone IMAGE:1624421 embryonic tissue 3' read A
AI032270.1 Clone IMAGE:1603810 lung 3' read
AI038256.1 Clone IMAGE:1672635 mixed 3' read P
AI040079.1 Clone IMAGE:1659934 embryonic tissue 3' read
AI040169.1 Clone IMAGE:1658992 embryonic tissue 3' read
AI057416.1 Clone IMAGE:1652691 mixed 3' read
AI131051.1 Clone IMAGE:1706657 heart 3' read P
AI143659.1 Clone IMAGE:1750652 brain 3' read
AI086361.1 Clone IMAGE:1678164 mixed 3' read A
BX091824.1 Clone IMAGp998G24976_;_IMAGE:417071 mixed P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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