> Tubulin, beta class I (TUBB)
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UGID:2143374     UniGene Hs.636480     Homo sapiens (human)   TUBB Order cDNA clone, Links
Tubulin, beta class I (TUBB)

Human protein-coding gene TUBB. Represented by 9904 ESTs from 804 cDNA libraries. Corresponds to reference sequence NM_178014.2. [UniGene 2143374 - Hs.636480]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_035785.1 Tubb5 gene product M. musculus 100.0 443
NP_775125.1 Tubb5 gene product R. norvegicus 100.0 443
XP_001368521.1 PREDICTED: tubulin beta chain-like isoform 1 M. domestica 100.0 443
XP_003227065.1 PREDICTED: tubulin beta chain-like A. carolinensis 100.0 443
XP_003966346.1 PREDICTED: tubulin beta chain-like T. rubripes 100.0 443
NP_942113.1 tubb5 gene product D. rerio 100.0 443
XP_004078045.1 PREDICTED: tubulin beta chain-like O. latipes 100.0 443
XP_003450643.1 PREDICTED: tubulin beta chain-like O. niloticus 100.0 443
NP_001080726.1 tubulin beta chain X. laevis 100.0 443
NP_001006895.1 tubb gene product X. tropicalis 100.0 443
NP_990646.1 TUBB gene product G. gallus 100.0 443
NP_001027985.1 TUBB gene product M. mulatta 100.0 443
XP_003897356.1 PREDICTED: tubulin beta chain isoform 1 P. anubis 100.0 443
NP_001038974.1 TUBB gene product P. troglodytes 100.0 443
NP_821133.1 TUBB gene product H. sapiens 100.0 443
XP_001491228.1 PREDICTED: tubulin beta chain isoform 1 E. caballus 100.0 443
NP_001038077.1 TUBB2A gene product S. scrofa 100.0 443
NP_001040014.1 TUBB gene product B. taurus 100.0 443
XP_004019033.1 PREDICTED: tubulin beta-5 chain isoform 1 O. aries 100.0 443
XP_002714405.1 PREDICTED: tubulin, beta 5-like O. cuniculus 100.0 443
NP_001133265.1 Tubulin beta chain S. salar 99.8 443
XP_002741272.1 PREDICTED: tubulin beta-3-like S. kowalevskii 99.5 446
XP_001632008.1 predicted protein N. vectensis 99.5 445
NP_001093160.1 TUBB2C gene product T. guttata 99.5 444
XP_848461.1 PREDICTED: tubulin beta-2C chain isoform 1 C. lupus familiaris 99.5 444
NP_523795.2 beta-Tubulin at 56D, isoform B D. melanogaster 98.4 446
NP_509585.1 Protein TBB-4 C. elegans 97.1 443
XP_001693997.1 beta tubulin 2 C. reinhardtii 92.3 442
NP_568959.1 tubulin beta-2/beta-3 chain A. thaliana 90.4 449
XP_957669.2 tubulin beta chain N. crassa 89.3 446
NP_116616.1 Tub2p S. cerevisiae 82.9 456
Other hits (2 of 48) [Show all]SpeciesId(%)Len(aa)
XP_003727239.1 PREDICTED: tubulin beta chain isoform 2 S. purpuratus 99.3 446
XP_002406661.1 beta tubulin I. scapularis 99.3 445

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; embryonic tissue; uncharacterized tissue; skin; eye; testis; lung; uterus; liver; placenta; lymph; kidney; blood; intestine; pancreas; ovary; thymus; mixed; prostate; mammary gland; stomach; muscle; connective tissue; cervix; bone; ascites; vascular; heart; lymph node; bone marrow; adrenal gland; spleen; pharynx; mouth; tonsil; bladder; thyroid; nerve; salivary gland; esophagus; larynx; ear; trachea; amniotic fluid; ganglia; umbilical cord; pituitary gland; adipose tissue; pineal gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 6
Map position: 6p21.33
UniSTS entry: Chr 6 D6S2041
UniSTS entry: Chr 6 SGC32809 [Map Viewer]
UniSTS entry: Chr 7 RH78383
UniSTS entry: Chr 6 IB1202 [Map Viewer]
UniSTS entry: Chr 6 SGC34396 [Map Viewer]
UniSTS entry: Chr 6 RH16171 [Map Viewer]
UniSTS entry: Chr 1 D3S3911
UniSTS entry: Tubb5
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (34)

AF070561.1 Homo sapiens clone 24703 beta-tubulin mRNA, complete cds PA
AF070593.1 Homo sapiens clones 24609 and 24716 beta-tubulin mRNA, complete cds PA
AF070600.1 Homo sapiens clone 24464 beta-tubulin mRNA, complete cds PA
NM_178014.2 Homo sapiens tubulin, beta class I (TUBB), mRNA PA
BC062532.1 Homo sapiens tubulin, beta, mRNA (cDNA clone IMAGE:3637650), complete cds PA
BC070326.1 Homo sapiens tubulin, beta, mRNA (cDNA clone MGC:88329 IMAGE:6698679), complete cds PA
AF141349.1 Homo sapiens beta-tubulin mRNA, complete cds P
BC103746.1 Homo sapiens tubulin, beta, mRNA (cDNA clone MGC:117247 IMAGE:6503977), complete cds PA
DQ457058.1 Homo sapiens XTP3TPA-transactivated protein 1 (XTP3TPATP1) mRNA, XTP3TPATP1-S allele, complete cds P
BC001938.1 Homo sapiens tubulin, beta, mRNA (cDNA clone MGC:4101 IMAGE:2820585), complete cds PA
BC001896.1 Homo sapiens tubulin, beta, mRNA (cDNA clone IMAGE:3544415), partial cds PA
BC002347.2 Homo sapiens tubulin, beta, mRNA (cDNA clone MGC:8668 IMAGE:2964461), complete cds PA
BC005838.2 Homo sapiens tubulin, beta, mRNA (cDNA clone MGC:2440 IMAGE:2820585), complete cds PA
BC007605.1 Homo sapiens tubulin, beta, mRNA (cDNA clone MGC:15683 IMAGE:3350604), complete cds PA
EF036509.1 Homo sapiens beta-4 tubulin mRNA, partial cds PA
BC013374.2 Homo sapiens tubulin, beta, mRNA (cDNA clone MGC:16435 IMAGE:3946253), complete cds PA
BC015889.1 Homo sapiens tubulin, beta, mRNA (cDNA clone IMAGE:3922098), partial cds PA
BC021909.1 Homo sapiens tubulin, beta, mRNA (cDNA clone MGC:15853 IMAGE:3509417), complete cds PA
BC020946.1 Homo sapiens tubulin, beta, mRNA (cDNA clone MGC:26663 IMAGE:4795692), complete cds PA
BC019924.1 Homo sapiens tubulin, beta, mRNA (cDNA clone MGC:30201 IMAGE:4998571), complete cds PA
AK309684.1 Homo sapiens cDNA, FLJ99725 P
AB062393.1 Homo sapiens OK/SW-cl.56 mRNA for beta 5-tubulin, complete cds PA
AK098772.1 Homo sapiens cDNA FLJ25906 fis, clone CBR04603, highly similar to TUBULIN BETA-5 CHAIN P
AK297638.1 Homo sapiens cDNA FLJ53063 complete cds, highly similar to Tubulin beta-7 chain P
AK297489.1 Homo sapiens cDNA FLJ53012 complete cds, highly similar to Tubulin beta-7 chain PA
AK298889.1 Homo sapiens cDNA FLJ50617 complete cds, highly similar to Tubulin beta-7 chain PA
AK303227.1 Homo sapiens cDNA FLJ52378 complete cds, highly similar to Tubulin beta-7 chain P
AK302314.1 Homo sapiens cDNA FLJ56903 complete cds, highly similar to Tubulin beta-7 chain PA
AK302195.1 Homo sapiens cDNA FLJ52029 complete cds, highly similar to Tubulin beta-7 chain P
BC029323.1 Homo sapiens tubulin, beta, mRNA (cDNA clone IMAGE:4705792) PA
BC001002.2 Homo sapiens tubulin, beta, mRNA (cDNA clone IMAGE:3447696) PA
AK316316.1 Homo sapiens cDNA, FLJ79215 complete cds, highly similar to Tubulin beta-7 chain P
AK316265.1 Homo sapiens cDNA, FLJ79164 complete cds, highly similar to Tubulin beta-7 chain P
V00599.1 Human mRNA fragment encoding beta-tubulin. (from clone D-beta-1) P

EST sequences (10 of 9904) [Show all sequences]

AA954817.1 Clone IMAGE:1574307 kidney 3' read
AA905720.1 Clone IMAGE:1506096 mixed 3' read
AA969180.1 Clone IMAGE:1581057 mixed 3' read A
AA969923.1 Clone IMAGE:1581153 mixed 3' read
AA975764.1 Clone IMAGE:1589450 kidney 3' read PA
AA977763.1 Clone IMAGE:1590649 kidney 3' read
AA983808.1 Clone IMAGE:1580973 mixed 3' read A
AA988221.1 Clone IMAGE:1604678 lung 3' read
R15283.1 Clone IMAGE:29877 brain 5' read
AA995389.1 Clone IMAGE:1601594 lung 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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