> Protein tyrosine phosphatase, non-receptor type 6 (PTPN6)
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UGID:139021     UniGene Hs.63489     Homo sapiens (human)   PTPN6 Order cDNA clone, Links
Protein tyrosine phosphatase, non-receptor type 6 (PTPN6)

Human protein-coding gene PTPN6. Represented by 547 ESTs from 189 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 139021 - Hs.63489]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_536859.1 PTPN6 gene product H. sapiens 100.0 623
XP_001163468.2 PREDICTED: tyrosine-protein phosphatase non-receptor type 6 isoform 1 P. troglodytes 100.0 596
XP_001110915.1 PREDICTED: tyrosine-protein phosphatase non-receptor type 6-like M. mulatta 99.5 596
NP_001071173.1 Ptpn6 gene product M. musculus 96.5 596
NP_956254.1 ptpn6 gene product D. rerio 73.0 588
NP_001167468.1 protein tyrosine phosphatase, non-receptor type 6 X. laevis 70.5 586
NP_477130.1 corkscrew, isoform A D. melanogaster 56.8 709
NP_001021944.1 Protein PTP-3, isoform c C. elegans 45.9 194
Other hits (2 of 36) [Show all]SpeciesId(%)Len(aa)
XP_003905937.1 PREDICTED: tyrosine-protein phosphatase non-receptor type 6 isoform 2 P. anubis 98.9 623
XP_001497756.2 PREDICTED: tyrosine-protein phosphatase non-receptor type 6 E. caballus 98.3 596

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: spleen; blood; uncharacterized tissue; lung; mixed; thymus; intestine; placenta; brain; thyroid; uterus; adrenal gland; liver; lymph; lymph node; bone marrow; embryonic tissue; connective tissue; pancreas; prostate; bladder; mouth; pharynx; mammary gland; tonsil; esophagus; testis; stomach; trachea; skin; ascites; kidney; amniotic fluid; heart; eye; muscle; bone; parathyroid; pineal gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 12
Map position: 12p13
UniSTS entry: Chr 12 RH46958
UniSTS entry: Chr 12 RH80060
UniSTS entry: Chr 12 RH79905
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (15)

M74903.1 Human hematopoietic cell phosphatase mRNA, complete cds P
M77273.1 Human tyrosine phosphatase mRNA, complete cds P
BT007390.1 Homo sapiens protein tyrosine phosphatase, non-receptor type 6 mRNA, complete cds P
NM_002831.5 Homo sapiens protein tyrosine phosphatase, non-receptor type 6 (PTPN6), transcript variant 1, mRNA PA
AK223629.1 Homo sapiens mRNA for protein tyrosine phosphatase, non-receptor type 6 isoform 1 variant, clone: FCC135A04 PA
BC002523.2 Homo sapiens protein tyrosine phosphatase, non-receptor type 6, mRNA (cDNA clone MGC:2332 IMAGE:3140265), complete cds PA
BC007667.2 Homo sapiens protein tyrosine phosphatase, non-receptor type 6, mRNA (cDNA clone MGC:2331 IMAGE:3138804), complete cds PA
NM_080549.3 Homo sapiens protein tyrosine phosphatase, non-receptor type 6 (PTPN6), transcript variant 3, mRNA PA
NM_080548.4 Homo sapiens protein tyrosine phosphatase, non-receptor type 6 (PTPN6), transcript variant 2, mRNA PA
AK290421.1 Homo sapiens cDNA FLJ77053 complete cds, highly similar to Homo sapiens protein tyrosine phosphatase, non-receptor type 6 (PTPN6), transcript variant 1, mRNA P
AK309037.1 Homo sapiens cDNA, FLJ99078
AK308230.1 Homo sapiens cDNA, FLJ98178 P
AK313379.1 Homo sapiens cDNA, FLJ93911, Homo sapiens protein tyrosine phosphatase, non-receptor type 6 (PTPN6), transcript variant 2, mRNA P
AK298470.1 Homo sapiens cDNA FLJ60320 complete cds, highly similar to Tyrosine-protein phosphatase non-receptor type6 (EC 3.1.3.48) PA
AK300167.1 Homo sapiens cDNA FLJ59423 complete cds, highly similar to Tyrosine-protein phosphatase non-receptor type6 (EC 3.1.3.48) P

EST sequences (10 of 547) [Show all sequences]

R15726.1 Clone IMAGE:66448 mixed 5' read
AA971623.1 Clone IMAGE:1584486 lung 3' read
AA975471.1 Clone IMAGE:1558191 lung 3' read A
AI040521.1 Clone IMAGE:1657133 mixed 3' read P
AI079670.1 Clone IMAGE:1668483 parathyroid 3' read PA
AI088105.1 Clone IMAGE:1566718 mixed 3' read PA
AA910515.1 Clone IMAGE:1517949 uncharacterized tissue 3' read A
AI123167.1 Clone IMAGE:1693647 heart 3' read A
AI123966.1 Clone IMAGE:1694861 uterus 3' read A
AI140749.1 Clone IMAGE:1690208 mixed 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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