> 2-hydroxyacyl-CoA lyase 1 (HACL1)
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UGID:139004     UniGene Hs.63290     Homo sapiens (human)   HACL1 Order cDNA clone, Links
2-hydroxyacyl-CoA lyase 1 (HACL1)

Human protein-coding gene HACL1. Represented by 522 ESTs from 221 cDNA libraries. Corresponds to reference sequence NM_012260.2. [UniGene 139004 - Hs.63290]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_036392.2 HACL1 gene product H. sapiens 100.0 577
XP_001160528.1 PREDICTED: 2-hydroxyacyl-CoA lyase 1 isoform 8 P. troglodytes 99.8 577
NP_064359.2 Hacl1 gene product M. musculus 90.5 580
NP_001086822.1 2-hydroxyacyl-CoA lyase 1 X. laevis 78.3 576
NP_998250.1 hacl1 gene product D. rerio 73.9 566
NP_611460.1 CG11208 D. melanogaster 62.7 565
NP_496455.2 Protein B0334.3, isoform b C. elegans 54.9 562
NP_197240.1 2-hydroxyacyl-CoA lyase A. thaliana 48.0 535
Other hits (2 of 47) [Show all]SpeciesId(%)Len(aa)
XP_003895186.1 PREDICTED: 2-hydroxyacyl-CoA lyase 1 isoform 1 P. anubis 97.8 577
XP_001082965.2 PREDICTED: 2-hydroxyacyl-CoA lyase 1 M. mulatta 96.2 478

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; connective tissue; uncharacterized tissue; intestine; thyroid; kidney; adrenal gland; heart; mixed; liver; muscle; pancreas; blood; lung; placenta; mammary gland; embryonic tissue; stomach; bladder; cervix; esophagus; larynx; trachea; uterus; prostate; vascular; eye; skin; bone marrow; ovary; thymus; spleen; pharynx; ascites; umbilical cord; bone; ear
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 3
Map position: 3p25.1
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (9)

NM_012260.2 Homo sapiens 2-hydroxyacyl-CoA lyase 1 (HACL1), mRNA PA
AJ131753.1 Homo sapiens mRNA for 2-hydroxyphytanoyl-CoA lyase PA
BC001627.1 Homo sapiens 2-hydroxyacyl-CoA lyase 1, mRNA (cDNA clone MGC:1115 IMAGE:3538159), complete cds PA
AK056977.1 Homo sapiens cDNA FLJ32415 fis, clone SKMUS2000724, highly similar to 2-hydroxyphytanoyl-CoA lyase (EC 4.1.-.-) P
AK301990.1 Homo sapiens cDNA FLJ54118 complete cds, highly similar to 2-hydroxyphytanoyl-CoA lyase (EC 4.1.-.-) PA
AK301546.1 Homo sapiens cDNA FLJ53672 complete cds, highly similar to 2-hydroxyphytanoyl-CoA lyase (EC 4.1.-.-) PA
AK302086.1 Homo sapiens cDNA FLJ58815 complete cds, highly similar to 2-hydroxyphytanoyl-CoA lyase (EC 4.1.-.-) P
BC007440.2 Homo sapiens 2-hydroxyacyl-CoA lyase 1, mRNA (cDNA clone IMAGE:2959666), complete cds PA
AF161397.1 Homo sapiens HSPC279 mRNA, partial cds PA

EST sequences (10 of 522) [Show all sequences]

AA970148.1 Clone IMAGE:1581827 mixed 3' read PA
AA999739.1 Clone IMAGE:1609120 mammary gland 3' read A
R17722.1 Clone IMAGE:31098 brain 5' read
AA927072.1 Clone IMAGE:1542214 mixed 3' read PA
AI023822.1 Clone IMAGE:1642660 testis 3' read PA
AI032530.1 Clone IMAGE:1654784 mixed 3' read PA
AI097390.1 Clone IMAGE:1702926 brain 3' read PA
AA909777.1 Clone IMAGE:1476567 uncharacterized tissue 3' read PA
AI143782.1 Clone IMAGE:1708310 heart 3' read PA
CB050025.1 Clone IMAGE:3271807 prostate 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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