> WD repeat domain 45 (WDR45)
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UGID:2139701     UniGene Hs.632807     Homo sapiens (human)   WDR45 Order cDNA clone, Links
WD repeat domain 45 (WDR45)

Human protein-coding gene WDR45. Represented by 465 ESTs from 248 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 2139701 - Hs.632807]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001105392.1 PREDICTED: WD repeat domain phosphoinositide-interacting protein 4-like isoform 1 M. mulatta 100.0 360
XP_001141338.2 PREDICTED: WD repeat domain phosphoinositide-interacting protein 4 isoform 3 P. troglodytes 100.0 360
NP_009006.2 WDR45 gene product H. sapiens 100.0 360
XP_003917741.1 PREDICTED: WD repeat domain phosphoinositide-interacting protein 4 P. anubis 100.0 359
XP_001495095.2 PREDICTED: WD repeat domain phosphoinositide-interacting protein 4 isoform 1 E. caballus 99.7 360
NP_001177222.1 WDR45 gene product S. scrofa 99.7 359
NP_001069619.1 WDR45 gene product B. taurus 99.7 359
XP_004022142.1 PREDICTED: WD repeat domain phosphoinositide-interacting protein 4 O. aries 99.7 359
NP_758960.1 Wdr45 gene product M. musculus 98.9 359
NP_956525.1 wdr45 gene product D. rerio 93.3 357
NP_001087011.1 WD repeat domain phosphoinositide-interacting protein 4 X. laevis 91.5 354
NP_649853.1 CG11975, isoform A D. melanogaster 47.0 300
Other hits (2 of 29) [Show all]SpeciesId(%)Len(aa)
XP_863889.1 PREDICTED: WD repeat domain phosphoinositide-interacting protein 4 isoform 4 C. lupus familiaris 99.2 359
XP_002719916.1 PREDICTED: WD repeat domain 45 O. cuniculus 98.5 332

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; lung; mixed; uncharacterized tissue; intestine; placenta; uterus; eye; liver; kidney; ovary; adrenal gland; vascular; heart; lymph node; mouth; testis; prostate; embryonic tissue; blood; larynx; cervix; spleen; stomach; connective tissue; thymus; pancreas; parathyroid; trachea; bone; skin; thyroid; mammary gland; spinal cord; bladder; salivary gland; lymph; ascites; muscle; adipose tissue; nerve; pharynx; bone marrow
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: X
Map position: Xp11.23
UniSTS entry: Chr X MARC_10039-10040:997207294:1
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (14)

AJ005897.1 Homo sapiens mRNA for JM5 protein, complete CDS (clone IMAGE 53337, LLNLc110F1857Q7 (RZPD Berlin) and LLNLc110G0913Q7 (RZPD Berlin)) P
NM_007075.3 Homo sapiens WD repeat domain 45 (WDR45), transcript variant 1, mRNA PA
BC069206.1 Homo sapiens WD repeat domain 45, mRNA (cDNA clone MGC:78551 IMAGE:5801768), complete cds PA
CR456725.1 Homo sapiens full open reading frame cDNA clone RZPDo834A0211D for gene JM5, JM5 protein; complete cds, incl. stopcodon P
AY691428.1 Homo sapiens WIPI-4 mRNA, complete cds P
NM_001029896.1 Homo sapiens WD repeat domain 45 (WDR45), transcript variant 2, mRNA PA
AK023344.1 Homo sapiens cDNA FLJ13282 fis, clone OVARC1001092, highly similar to Homo sapiens mRNA for JM5 protein P
BC003037.1 Homo sapiens WD repeat domain 45, mRNA (cDNA clone MGC:4360 IMAGE:2822742), complete cds PA
BC000464.2 Homo sapiens WD repeat domain 45, mRNA (cDNA clone MGC:8542 IMAGE:2822742), complete cds PA
AK225122.1 Homo sapiens mRNA for WD repeat domain 45 isoform 2 variant, clone: CBL02426 PA
BC009027.1 Homo sapiens WD repeat domain 45, mRNA (cDNA clone IMAGE:4156276), partial cds PA
AK315717.1 Homo sapiens cDNA, FLJ96819 P
AK301084.1 Homo sapiens cDNA FLJ57611 complete cds, moderately similar to WD repeat domain phosphoinositide-interacting protein 4 P
BC035979.1 Homo sapiens WD repeat domain 45, mRNA (cDNA clone IMAGE:4657761), with apparent retained intron PA

EST sequences (10 of 465) [Show all sequences]

R15929.1 Clone IMAGE:53337 brain 5' read P
AA974520.1 Clone IMAGE:1421008 intestine 3' read
AA983705.1 Clone IMAGE:1557606 lung 3' read P
AA995334.1 Clone IMAGE:1604878 lung 3' read A
AI077836.1 Clone IMAGE:1665480 skin 3' read A
AI092278.1 Clone IMAGE:1683352 parathyroid 3' read A
AI194031.1 Clone IMAGE:1745074 lung 3' read A
AI268080.1 Clone IMAGE:1911557 lung 3' read A
CB162777.1 Clone L17N670205n1-31-C03 liver 5' read P
CB160787.1 Clone L18POOL1n1-23-H02 liver 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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