> Hypermethylated in cancer 2 (HIC2)
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UGID:2139661     UniGene Hs.632767     Homo sapiens (human)   HIC2 Order cDNA clone, Links
Hypermethylated in cancer 2 (HIC2)

Human protein-coding gene HIC2. Represented by 170 ESTs from 72 cDNA libraries. Corresponds to reference sequence NM_015094.2. [UniGene 2139661 - Hs.632767]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_055909.2 HIC2 gene product H. sapiens 100.0 614
NP_849253.2 Hic2 gene product M. musculus 89.7 618
NP_878289.2 hic2 gene product D. rerio 65.2 559
NP_001090444.1 hypermethylated in cancer 2 X. laevis 63.4 448
Other hits (2 of 19) [Show all]SpeciesId(%)Len(aa)
XP_515003.2 PREDICTED: hypermethylated in cancer 2 protein isoform 2 P. troglodytes 99.2 614
XP_003905315.1 PREDICTED: hypermethylated in cancer 2 protein isoform 1 P. anubis 98.9 614

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: mixed; placenta; brain; lung; uncharacterized tissue; cervix; blood; bladder; ear; eye; testis; thymus; mammary gland; pituitary gland; embryonic tissue; uterus; skin; heart; pancreas; intestine; kidney; muscle; spleen; connective tissue; adipose tissue; parathyroid
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 22
Map position: 22q11.21
UniSTS entry: Chr 22 A006G19
UniSTS entry: Chr 22 G20786
UniSTS entry: Chr 22 A009D08 [Map Viewer]
UniSTS entry: Chr 22 HIC2__6718
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (10)

AB028943.2 Homo sapiens mRNA for KIAA1020 protein, partial cds P
NM_015094.2 Homo sapiens hypermethylated in cancer 2 (HIC2), mRNA PA
AL162003.1 Homo sapiens mRNA; cDNA DKFZp434F0616 (from clone DKFZp434F0616); partial cds PA
CR456377.1 Homo sapiens Em:AP000557.1 full length open reading frame (ORF) cDNA clone (cDNA clone C22ORF:pGEM.Em:AP000557.1.V3) P
BC094787.1 Homo sapiens hypermethylated in cancer 2, mRNA (cDNA clone MGC:104729 IMAGE:30531041), complete cds PA
AK023021.1 Homo sapiens cDNA FLJ12959 fis, clone NT2RP2005600, highly similar to Homo sapiens mRNA for KIAA1020 protein
BC009216.2 Homo sapiens cDNA clone IMAGE:3842332, partial cds A
BC009207.2 Homo sapiens hypermethylated in cancer 2, mRNA (cDNA clone IMAGE:3629289), partial cds A
AF349035.2 Homo sapiens HIC-3 mRNA, complete cds P
AJ313204.1 Homo sapiens mRNA for HRG22 protein P

EST sequences (10 of 170) [Show all sequences]

AA970950.1 Clone IMAGE:1581849 mixed 3' read A
AI024449.1 Clone IMAGE:1641715 testis 3' read
AI056611.1 Clone IMAGE:1674970 mixed 3' read
AI061283.1 Clone IMAGE:1699733 kidney 3' read A
AI127785.1 Clone IMAGE:1711291 uterus 3' read A
BX093473.1 Clone IMAGp998J131961_;_IMAGE:795372 testis
AI218627.1 Clone IMAGE:1753737 testis 3' read A
AI273282.1 Clone IMAGE:1876190 mixed 3' read
AI377678.1 Clone IMAGE:2090803 mixed 3' read A
AI378476.1 Clone IMAGE:2068641 mixed 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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