Four and a half LIM domains 5 (FHL5)

Restricted Expression:

fetus [show more like this]

EST Profile:

Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]

GEO Profiles:

Experimental gene expression data (Gene Expression Omnibus).

cDNA Sources:

testis; brain; uterus; mixed; vascular; connective tissue; kidney; trachea; intestine; stomach; prostate; thymus; nerve; lung; heart

NCBI

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Finding cDNAs

UGID:2139502 UniGene Hs.632608 Homo sapiens (human) FHL5

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Four and a half LIM domains 5 (FHL5)

Human protein-coding gene FHL5. Represented by 140 ESTs from 34 cDNA libraries. EST representation biased toward fetus. Corresponds to 2 reference sequences (different isoforms). [UniGene 2139502 - Hs.632608]

SELECTED PROTEIN SIMILARITIES

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.

Best Hits and Hits from model organisms		Species	Id(%)	Len(aa)
NP_065228.4 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	FHL5 gene product	H. sapiens	100.0	283
NP_001233299.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	FHL5 gene product	P. troglodytes	99.7	283
NP_067293.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Fhl5 gene product	M. musculus	89.8	283
NP_001003732.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	fhl2a gene product	D. rerio	68.7	275
NP_001087877.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	four and a half LIM domains 5	X. laevis	68.7	274
NP_996111.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	limpet, isoform F	D. melanogaster	51.1	274
NP_001021408.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Protein LIM-9, isoform d	C. elegans	48.9	227
Other hits (2 of 35) [Show all]		Species	Id(%)	Len(aa)
XP_001100497.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: four and a half LIM domains protein 5 isoform 1	M. mulatta	99.3	283
XP_003897978.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: four and a half LIM domains protein 5 isoform 1	P. anubis	99.3	283

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

	Chromosome:	6
	Map position:	6q16.1-q16.3

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (9)

AF278541.1	Homo sapiens LIM protein ACT mRNA, complete cds	P
AK223539.1	Homo sapiens mRNA for activator of cAMP-responsive element modulator (CREM) in testis variant, clone: FCC125B10	P
NM_020482.4	Homo sapiens four and a half LIM domains 5 (FHL5), transcript variant 1, mRNA	PA
AK058175.1	Homo sapiens cDNA FLJ25446 fis, clone TST08605, highly similar to Homo sapiens LIM protein ACT mRNA	P
AK057611.1	Homo sapiens cDNA FLJ33049 fis, clone TRACH1000038, highly similar to Four and a half LIM domains protein 5	P
BC021723.2	Homo sapiens four and a half LIM domains 5, mRNA (cDNA clone MGC:33058 IMAGE:4827311), complete cds	PA
AK314608.1	Homo sapiens cDNA, FLJ95447, highly similar to Homo sapiens activator of cAMP-responsive element modulator (CREM) in testis (ACT), mRNA	P
BC029490.1	Homo sapiens four and a half LIM domains 5, mRNA (cDNA clone MGC:32991 IMAGE:5273208), complete cds	PA
NM_001170807.1	Homo sapiens four and a half LIM domains 5 (FHL5), transcript variant 2, mRNA	PA

EST sequences (10 of 140) [Show all sequences]

AI066578.1	Clone IMAGE:1640494	testis	3' read	A
BX118021.1	Clone IMAGp998G234162_;_IMAGE:1640494	testis		A
AI190895.1	Clone IMAGE:1733988	testis	3' read	P
AI424871.1	Clone IMAGE:2111081	mixed	3' read	A
AI425084.1	Clone IMAGE:2111130	mixed	3' read	P
AI784680.1	Clone IMAGE:2043013	uterus	3' read	A
AI823512.1	Clone IMAGE:2384613	kidney	3' read	A
CD171872.1	Clone IMAGE:30378836	testis	5' read	P
AW629165.1	Clone IMAGE:2975878	mixed	3' read	P
AW771484.1	Clone IMAGE:3031978	kidney	3' read	A

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria