> Discoidin domain receptor tyrosine kinase 1 (DDR1)
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UGID:2138882     UniGene Hs.631988     Homo sapiens (human)   DDR1 Order cDNA clone, Links
Discoidin domain receptor tyrosine kinase 1 (DDR1)

Human protein-coding gene DDR1. Represented by 1321 ESTs from 289 cDNA libraries. Corresponds to 6 reference sequences (different isoforms). [UniGene 2138882 - Hs.631988]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_054700.2 DDR1 gene product H. sapiens 100.0 918
NP_001038967.1 epithelial discoidin domain-containing receptor 1 precursor P. troglodytes 100.0 908
NP_001108424.1 epithelial discoidin domain-containing receptor 1 precursor M. mulatta 99.9 874
NP_001185760.1 Ddr1 gene product M. musculus 97.3 910
XP_001345829.4 PREDICTED: epithelial discoidin domain-containing receptor 1 D. rerio 72.5 935
NP_001083540.1 discoidin domain receptor tyrosine kinase 1 precursor X. laevis 72.0 936
NP_508573.1 Protein DDR-2, isoform b C. elegans 54.8 219
NP_476962.1 Ror D. melanogaster 47.8 230
Other hits (2 of 38) [Show all]SpeciesId(%)Len(aa)
XP_003897362.1 PREDICTED: LOW QUALITY PROTEIN: epithelial discoidin domain-containing receptor 1 P. anubis 99.3 954
XP_001490848.2 PREDICTED: epithelial discoidin domain-containing receptor 1 isoform 3 E. caballus 97.8 919

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; mouth; trachea; pancreas; embryonic tissue; placenta; mammary gland; intestine; uterus; thymus; lung; pharynx; eye; mixed; uncharacterized tissue; ovary; skin; heart; prostate; bladder; spleen; muscle; larynx; liver; connective tissue; kidney; stomach; thyroid; cervix; esophagus; amniotic fluid; epididymis; ear; ascites; salivary gland; nerve; pineal gland; lymph node; adrenal gland; pituitary gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 6
Map position: 6p21.3
UniSTS entry: Chr 6 RH70253 [Map Viewer]
UniSTS entry: Chr 6 RH46779 [Map Viewer]
UniSTS entry: Chr 6 D6S2203
UniSTS entry: Chr 6 RH11020 [Map Viewer]
UniSTS entry: Chr 6 RH18132
UniSTS entry: Chr 6 WI-18751 [Map Viewer]
UniSTS entry: Chr 6 D6S1851 [Map Viewer]
UniSTS entry: Chr 6 GDB:594103
UniSTS entry: fk81c03.x1
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (23)

L11315.1 Homo sapiens receptor tyrosine kinase mRNA, complete cds P
AK130776.1 Homo sapiens cDNA FLJ27266 fis, clone TMS00356, highly similar to Epithelial discoidin domain receptor 1 precursor (EC 2.7.1.112) P
NM_001954.4 Homo sapiens discoidin domain receptor tyrosine kinase 1 (DDR1), transcript variant 1, mRNA PA
BC070070.1 Homo sapiens discoidin domain receptor tyrosine kinase 1, mRNA (cDNA clone MGC:87336 IMAGE:5262509), complete cds PA
NM_013993.2 Homo sapiens discoidin domain receptor tyrosine kinase 1 (DDR1), transcript variant 2, mRNA PA
NM_013994.2 Homo sapiens discoidin domain receptor tyrosine kinase 1 (DDR1), transcript variant 3, mRNA PA
AB210021.1 Homo sapiens mRNA for DDR1 variant protein, partial cds, clone: fk11093 P
Z29093.1 H.sapiens EDDR1 gene for receptor tyrosine kinase PA
L57508.1 Homo sapiens Cak receptor kinase mRNA, complete cds PA
AF353182.1 Homo sapiens discoidin domain receptor DDR1d (DDR1) mRNA, partial cds, alternatively spliced P
BC008716.2 Homo sapiens discoidin domain receptor tyrosine kinase 1, mRNA (cDNA clone MGC:8681 IMAGE:2964574), complete cds PA
BC013400.2 Homo sapiens discoidin domain receptor tyrosine kinase 1, mRNA (cDNA clone MGC:3909 IMAGE:2964574), complete cds PA
AK291621.1 Homo sapiens cDNA FLJ75091 complete cds, highly similar to Homo sapiens discoidin domain receptor family, member 1 (DDR1),transcript variant 2, mRNA P
L20817.1 Homo sapiens tyrosine protein kinase (CAK) gene, complete cds PA
EU826614.1 Homo sapiens soluble DDR1 variant 2 (DDR1) mRNA, complete cds, alternatively spliced P
EU826613.1 Homo sapiens soluble DDR1 variant 1 (DDR1) mRNA, complete cds, alternatively spliced P
AF353183.1 Homo sapiens discoidin domain receptor DDR1e (DDR1) mRNA, partial cds, alternatively spliced
AK295643.1 Homo sapiens cDNA FLJ54797 complete cds, highly similar to Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) P
AK294793.1 Homo sapiens cDNA FLJ56035 complete cds, highly similar to Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) P
X74979.1 H.sapiens TRK E mRNA PA
NM_001202523.1 Homo sapiens discoidin domain receptor tyrosine kinase 1 (DDR1), transcript variant 6, mRNA PA
NM_001202522.1 Homo sapiens discoidin domain receptor tyrosine kinase 1 (DDR1), transcript variant 5, mRNA PA
NM_001202521.1 Homo sapiens discoidin domain receptor tyrosine kinase 1 (DDR1), transcript variant 4, mRNA PA

EST sequences (10 of 1321) [Show all sequences]

BX109317.1 Clone IMAGp998A09338_;_IMAGE:182288 mammary gland
AI214511.1 Clone IMAGE:1883100 lung 3' read A
AI251921.1 Clone IMAGE:1977967 brain 3' read A
CB159423.1 Clone L18POOL1n1-40-E07 liver 5' read
R31229.1 Clone IMAGE:134328 placenta 5' read
AI275058.1 Clone IMAGE:1877867 mixed 3' read A
CB127505.1 Clone C1SNU17-20-H04 cervix 5' read P
CB122454.1 Clone L10ChoCK0-21-H12 liver 5' read
CB129633.1 Clone L11SNU354-16-B12 liver 5' read P
CB141830.1 Clone L11SNU354s1-24-F02 liver 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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