> NIMA-related kinase 4 (NEK4)
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UGID:2138815     UniGene Hs.631921     Homo sapiens (human)   NEK4 Order cDNA clone, Links
NIMA-related kinase 4 (NEK4)

Human protein-coding gene NEK4. Represented by 255 ESTs from 101 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 2138815 - Hs.631921]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_003148.2 NEK4 gene product H. sapiens 100.0 840
NP_035979.1 Nek4 gene product M. musculus 85.1 791
NP_957306.1 nek4 gene product D. rerio 64.5 844
NP_001084575.1 NIMA-related kinase 4 X. laevis 64.2 784
NP_198181.1 serine/threonine-protein kinase Nek3 A. thaliana 48.4 256
XP_001700340.1 predicted protein C. reinhardtii 47.1 246
NP_490968.2 Protein NEKL-1 C. elegans 45.4 185
Other hits (2 of 45) [Show all]SpeciesId(%)Len(aa)
XP_516519.4 PREDICTED: serine/threonine-protein kinase Nek4 isoform 2 P. troglodytes 99.4 780
XP_003894352.1 PREDICTED: serine/threonine-protein kinase Nek4 P. anubis 97.2 780

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: testis; brain; placenta; uterus; esophagus; thyroid; stomach; skin; spleen; eye; embryonic tissue; uncharacterized tissue; kidney; lung; mouth; adrenal gland; blood; trachea; mammary gland; thymus; pharynx; intestine; bladder; connective tissue; ascites; liver; bone; adipose tissue; heart; pancreas; mixed; lymph node
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 3
Map position: 3p21.1
UniSTS entry: Chr 3 SHGC-77006 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (8)

L20321.1 Human protein serine/threonine kinase stk2 mRNA, complete cds P
NM_003157.4 Homo sapiens NIMA-related kinase 4 (NEK4), transcript variant 1, mRNA P
BC063044.1 Homo sapiens NIMA (never in mitosis gene a)-related kinase 4, mRNA (cDNA clone MGC:65120 IMAGE:5169184), complete cds PA
EF560744.1 Homo sapiens clone IMAGp998G0211678 NEK4 protein (NEK4) mRNA, complete cds P
AK312420.1 Homo sapiens cDNA, FLJ92759, highly similar to Homo sapiens NIMA (never in mitosis gene a)-related kinase 4 (NEK4), mRNA P
BC015515.1 Homo sapiens NIMA (never in mitosis gene a)-related kinase 4, mRNA (cDNA clone IMAGE:3913546), partial cds PA
AK294165.1 Homo sapiens cDNA FLJ53862 complete cds, highly similar to Homo sapiens NIMA (never in mitosis gene a)-related kinase 4 (NEK4), mRNA P
NM_001193533.1 Homo sapiens NIMA-related kinase 4 (NEK4), transcript variant 2, mRNA P

EST sequences (10 of 255) [Show all sequences]

AA886466.1 Clone IMAGE:1500063 lung 3' read
CB159682.1 Clone L18POOL1n1-25-G01 liver 5' read
CB120617.1 Clone L8SCK0-36-A04 liver 5' read P
AA888344.1 Clone IMAGE:1252245 bone A
CB218284.1 Clone IMAGE:5795532 bone 3' read A
AI453246.1 Clone IMAGE:2143956 pancreas 3' read A
AI634501.1 Clone IMAGE:2273183 lung 3' read P
AI561033.1 Clone IMAGE:2210228 uterus 3' read P
CB269744.1 adipose tissue 5' read P
BX282416.1 Clone IMAGp998G0713344_;_IMAGE:6066462 uncharacterized tissue P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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