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UGID:138923     UniGene Hs.62185     Homo sapiens (human)   SLC9A6
Solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6 (SLC9A6)

Human protein-coding gene SLC9A6. Represented by 246 ESTs from 119 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 138923 - Hs.62185]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001036002.1 SLC9A6 gene product H. sapiens 100.0 700
XP_529172.3 PREDICTED: sodium/hydrogen exchanger 6 P. troglodytes 100.0 529
XP_001101721.1 PREDICTED: sodium/hydrogen exchanger 6-like isoform 4 M. mulatta 99.9 700
XP_003918372.1 PREDICTED: sodium/hydrogen exchanger 6 isoform 1 P. anubis 99.9 700
XP_002720367.1 PREDICTED: solute carrier family 9 (sodium/hydrogen exchanger), member 6-like isoform 1 O. cuniculus 99.6 700
XP_004022365.1 PREDICTED: sodium/hydrogen exchanger 6 O. aries 99.5 595
NP_766368.2 Slc9a6 gene product M. musculus 99.4 698
NP_001091726.2 solute carrier family 9 (sodium/hydrogen exchanger), member 6a precursor D. rerio 85.1 684
NP_001137801.1 Na[+]/H[+] hydrogen exchanger 3, isoform G D. melanogaster 59.2 659
NP_001024721.1 Protein NHX-5, isoform b C. elegans 49.9 449
NP_178079.2 sodium/hydrogen exchanger 6 A. thaliana 45.9 181
XP_956772.2 hypothetical protein NCU00453 N. crassa 45.7 173
Other hits (2 of 36) [Show all]SpeciesId(%)Len(aa)
NP_001094616.1 SLC9A6 gene product B. taurus 99.4 701
XP_538181.4 PREDICTED: LOW QUALITY PROTEIN: sodium/hydrogen exchanger 6 C. lupus familiaris 99.3 702

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; uncharacterized tissue; lung; testis; eye; kidney; mixed; heart; pancreas; intestine; muscle; vascular; ovary; skin; uterus; lymph node; embryonic tissue; mouth; blood; thymus; trachea; bladder; thyroid; placenta; parathyroid; stomach; ear; connective tissue; nerve; ganglia; prostate; bone; liver; pineal gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: X
Map position: Xq26.3
UniSTS entry: Chr X SHGC-31813 [Map Viewer]
UniSTS entry: Chr X SLC9A6_3766
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (15)

BC047375.1 Homo sapiens cDNA clone IMAGE:5274057, containing frame-shift errors PA
BC049169.1 Homo sapiens solute carrier family 9 (sodium/hydrogen exchanger), member 6, mRNA (cDNA clone MGC:57187 IMAGE:5312949), complete cds PA
NM_006359.2 Homo sapiens solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6 (SLC9A6), transcript variant 2, mRNA PA
NM_001042537.1 Homo sapiens solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6 (SLC9A6), transcript variant 1, mRNA PA
AK289775.1 Homo sapiens cDNA FLJ75020 complete cds, highly similar to Homo sapiens solute carrier family 9 (sodium/hydrogen exchanger), member 6, mRNA P
AK314562.1 Homo sapiens cDNA, FLJ95386 P
AK300475.1 Homo sapiens cDNA FLJ50678 complete cds, highly similar to Sodium/hydrogen exchanger 6 P
AK297218.1 Homo sapiens cDNA FLJ51895 complete cds, highly similar to Sodium/hydrogen exchanger 6 P
AK296444.1 Homo sapiens cDNA FLJ54617 complete cds, highly similar to Homo sapiens solute carrier family 9 (sodium/hydrogen exchanger), member 6, transcript variant 1, mRNA P
AB074255.1 Homo sapiens mRNA for NHE6.1, partial cds P
AK316255.1 Homo sapiens cDNA, FLJ79154 complete cds, highly similar to Sodium/hydrogen exchanger 6 P
BC035029.1 Homo sapiens solute carrier family 9 (sodium/hydrogen exchanger), member 6, mRNA (cDNA clone MGC:33775 IMAGE:5264865), complete cds PA
D87743.1 Homo sapiens mRNA for KIAA0267 gene, partial cds P
NM_001177651.1 Homo sapiens solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6 (SLC9A6), transcript variant 3, mRNA PA
AF030409.1 Homo sapiens sodium-hydrogen exchanger 6 (NHE-6) mRNA, nuclear gene encoding mitochondrial protein, complete cds P

EST sequences (10 of 246) [Show all sequences]

AA954490.1 Clone IMAGE:1563049 mixed 3' read A
AA863429.1 Clone IMAGE:1456914 kidney 3' read A
R15803.1 Clone IMAGE:53207 brain 3' read A
AA976806.1 Clone IMAGE:1586897 uncharacterized tissue 3' read
AA984080.1 Clone IMAGE:1616367 brain 3' read
AA984095.1 Clone IMAGE:1616391 brain 3' read
AI003195.1 Clone IMAGE:1685356 brain 3' read
AA927368.1 Clone IMAGE:1552473 uncharacterized tissue 3' read A
T26487.1 Clone LLAB231G12 brain 5' read
R20442.1 Clone IMAGE:34222 brain 5' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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