> Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (NFKB1)
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UGID:2087441     UniGene Hs.618430     Homo sapiens (human)   NFKB1 Order cDNA clone, Links
Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (NFKB1)

Human protein-coding gene NFKB1. Represented by 381 ESTs from 198 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 2087441 - Hs.618430]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001168718.1 PREDICTED: nuclear factor NF-kappa-B p105 subunit isoform 10 P. troglodytes 100.0 968
NP_003989.2 NFKB1 gene product H. sapiens 100.0 968
NP_001252982.1 nuclear factor NF-kappa-B p105 subunit M. mulatta 99.8 968
XP_003899071.1 PREDICTED: nuclear factor NF-kappa-B p105 subunit P. anubis 99.8 968
NP_032715.2 Nfkb1 gene product M. musculus 94.3 970
NP_001087808.1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 X. laevis 75.5 932
XP_003200023.1 PREDICTED: nuclear factor NF-kappa-B p105 subunit, partial D. rerio 68.7 393
NP_724052.1 dorsal, isoform A D. melanogaster 50.6 162
Other hits (2 of 25) [Show all]SpeciesId(%)Len(aa)
XP_001514381.2 PREDICTED: nuclear factor NF-kappa-B p105 subunit-like, partial O. anatinus 96.7 271
NP_001041697.1 NFKB1 gene product S. scrofa 96.5 958

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: uncharacterized tissue; mixed; embryonic tissue; adrenal gland; mouth; spleen; vascular; eye; bone; amniotic fluid; pharynx; thyroid; trachea; thymus; testis; lung; placenta; uterus; pancreas; brain; blood; heart; intestine; connective tissue; mammary gland; liver; lymph node; bone marrow; parathyroid; kidney; skin; prostate; bladder; tonsil; cervix; lymph; muscle; nerve; stomach; ovary; salivary gland; ganglia
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 4
Map position: 4q24
UniSTS entry: Chr 4 SHGC-12798 [Map Viewer]
UniSTS entry: Chr 4 NFKB1
UniSTS entry: Chr 1 SHGC-30224 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (9)

M58603.1 Human nuclear factor kappa-B DNA binding subunit (NF-kappa-B) mRNA, complete cds P
M55643.1 Human factor KBF1 mRNA, complete cds P
BC051765.1 Homo sapiens nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, mRNA (cDNA clone MGC:54151 IMAGE:6500087), complete cds PA
AK122850.1 Homo sapiens cDNA FLJ16470 fis, clone BRHIP3009181, highly similar to NUCLEAR FACTOR NF-KAPPA-B P105 SUBUNIT P
CR749522.1 Homo sapiens mRNA; cDNA DKFZp686C01211 (from clone DKFZp686C01211) PA
NM_003998.3 Homo sapiens nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (NFKB1), transcript variant 1, mRNA PA
AK291450.1 Homo sapiens cDNA FLJ78654 complete cds, highly similar to Homo sapiens nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) (NFKB1), mRNA P
BC033210.1 Homo sapiens nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, mRNA (cDNA clone IMAGE:4906270), partial cds PA
NM_001165412.1 Homo sapiens nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (NFKB1), transcript variant 2, mRNA PA

EST sequences (10 of 381) [Show all sequences]

AI074106.1 Clone IMAGE:1679128 skin 3' read A
AI076882.1 Clone IMAGE:1670273 brain 3' read A
AI079695.1 Clone IMAGE:1668515 parathyroid 3' read
AI093820.1 Clone IMAGE:1688487 mixed 3' read P
AI086214.1 Clone IMAGE:1654097 mixed 3' read
BX113675.1 Clone IMAGp998G13560_;_IMAGE:257316 placenta P
R26146.1 Clone IMAGE:133109 placenta 3' read
R26360.1 Clone IMAGE:133109 placenta 5' read
AI208178.1 Clone IMAGE:1839062 testis 3' read
AI262293.1 Clone IMAGE:1870817 intestine 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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