> Rho guanine nucleotide exchange factor (GEF) 25 (ARHGEF25)
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UGID:138865     UniGene Hs.61581     Homo sapiens (human)   ARHGEF25 Order cDNA clone, Links
Rho guanine nucleotide exchange factor (GEF) 25 (ARHGEF25)

Human protein-coding gene ARHGEF25. Represented by 113 ESTs from 58 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 138865 - Hs.61581]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001167786.1 PREDICTED: rho guanine nucleotide exchange factor 25 isoform 2 P. troglodytes 100.0 618
NP_001104740.1 ARHGEF25 gene product H. sapiens 100.0 618
NP_082303.2 rho guanine nucleotide exchange factor 25 isoform 1 M. musculus 92.4 617
XP_698049.4 PREDICTED: rho guanine nucleotide exchange factor 25 D. rerio 67.3 545
NP_001121262.1 kalirin, RhoGEF kinase X. laevis 59.5 511
NP_001021499.1 Protein UNC-73, isoform d C. elegans 49.6 282
NP_728563.1 trio, isoform E D. melanogaster 46.5 202
Other hits (2 of 33) [Show all]SpeciesId(%)Len(aa)
XP_003906721.1 PREDICTED: rho guanine nucleotide exchange factor 25 isoform 2 P. anubis 98.5 618
XP_001100987.2 PREDICTED: guanine nucleotide exchange factor GEFT-like M. mulatta 97.2 596

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; uncharacterized tissue; ascites; stomach; mixed; testis; intestine; uterus; ganglia; prostate; pancreas; embryonic tissue; placenta; lung; eye; pituitary gland; ovary; bone; heart
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 12
Map position: 12q13.3
UniSTS entry: Chr 12 RH94136
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (8)

AF487514.2 Homo sapiens RAC/CDC42/Rho exchange factor GEFT mRNA, complete cds PA
BC047559.1 Homo sapiens RhoA/RAC/CDC42 exchange factor, mRNA (cDNA clone MGC:44765 IMAGE:5311038), complete cds PA
NM_182947.3 Homo sapiens Rho guanine nucleotide exchange factor (GEF) 25 (ARHGEF25), transcript variant 1, mRNA PA
BC012860.1 Homo sapiens RhoA/RAC/CDC42 exchange factor, mRNA (cDNA clone MGC:18298 IMAGE:4179764), complete cds PA
BC018536.1 Homo sapiens RhoA/RAC/CDC42 exchange factor, mRNA (cDNA clone IMAGE:4213812), partial cds PA
AB370196.1 Homo sapiens GEFT mRNA for RAC/CDC42/Rho exchange factor, complete cds PA
NM_001111270.2 Homo sapiens Rho guanine nucleotide exchange factor (GEF) 25 (ARHGEF25), transcript variant 3, mRNA PA
NR_046223.1 Homo sapiens Rho guanine nucleotide exchange factor (GEF) 25 (ARHGEF25), transcript variant 4, non-coding RNA PA

EST sequences (10 of 113) [Show all sequences]

AA906309.1 Clone IMAGE:1506751 mixed 3' read A
AI089627.1 Clone IMAGE:1696452 uterus 3' read A
AI141311.1 Clone IMAGE:1669339 brain 3' read A
BX112080.1 Clone IMAGp998B051116_;_IMAGE:470692 uterus A
AI217285.1 Clone IMAGE:1845675 mixed 3' read A
AI298483.1 Clone IMAGE:1896514 lung 3' read A
AI338780.1 Clone IMAGE:1951710 lung 3' read A
AI366527.1 Clone IMAGE:1955620 brain 3' read
AI374899.1 Clone IMAGE:2048513 embryonic tissue 3' read A
AI382756.1 Clone IMAGE:2063223 mixed 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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