> Cathepsin A (CTSA)
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UGID:2078347     UniGene Hs.609336     Homo sapiens (human)   CTSA Order cDNA clone, Links
Cathepsin A (CTSA)

Human protein-coding gene CTSA. Represented by 1828 ESTs from 489 cDNA libraries. Corresponds to 4 reference sequences (different isoforms). [UniGene 2078347 - Hs.609336]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_000299.2 CTSA gene product H. sapiens 100.0 497
XP_525342.1 PREDICTED: neuralized-like protein 2 P. troglodytes 100.0 284
XP_001106032.1 PREDICTED: lysosomal protective protein-like isoform 5 M. mulatta 99.6 493
XP_003904717.1 PREDICTED: lysosomal protective protein isoform 1 P. anubis 99.6 493
NP_032932.2 Ctsa gene product M. musculus 99.2 491
NP_956844.1 ctsa gene product D. rerio 76.4 470
NP_001088109.1 cathepsin A precursor X. laevis 75.6 467
NP_495284.1 Protein K10B2.2, isoform a C. elegans 55.8 276
NP_191213.1 putative serine carboxypeptidase-like 53 A. thaliana 49.1 173
XP_956796.1 carboxypeptidase Y precursor N. crassa 48.8 162
NP_009697.3 carboxypeptidase C S. cerevisiae 48.2 164
XP_001703566.1 predicted protein C. reinhardtii 45.4 174
Other hits (2 of 46) [Show all]SpeciesId(%)Len(aa)
XP_001916911.2 PREDICTED: lysosomal protective protein E. caballus 95.8 476
NP_001103385.1 lysosomal protective protein precursor C. lupus familiaris 94.6 498

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; uncharacterized tissue; skin; intestine; placenta; lung; testis; uterus; mixed; kidney; mammary gland; pancreas; connective tissue; stomach; liver; adrenal gland; blood; ovary; heart; embryonic tissue; thymus; bone; prostate; mouth; ascites; eye; lymph node; larynx; cervix; bladder; spleen; thyroid; muscle; trachea; pharynx; umbilical cord; esophagus; vascular; bone marrow; pituitary gland; epididymis; ganglia; salivary gland; pineal gland; parathyroid; adipose tissue; nerve
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 20
Map position: 20q13.1
UniSTS entry: Chr 20 D20S1030 [Map Viewer]
UniSTS entry: Chr 20 STS-M22960
UniSTS entry: Chr 20 Cda16d10 [Map Viewer]
UniSTS entry: Chr 20 G64282
UniSTS entry: GDB:193197
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (19)

AJ295985.1 Homo sapiens mRNA for hypothetical protein (ORF1), clone Telethon(Italy_B41)_Strait28873_FL402 P
M22960.1 Human protective protein mRNA, complete cds P
NM_000308.2 Homo sapiens cathepsin A (CTSA), transcript variant 1, mRNA PA
AK172808.1 Homo sapiens cDNA FLJ23969 fis, clone HEP16905, highly similar to Lysosomal protective protein precursor (EC 3.4.16.5) PA
BC074737.2 Homo sapiens neuralized homolog 2 (Drosophila), mRNA (cDNA clone MGC:103813 IMAGE:30915194), complete cds P
AB209705.2 Homo sapiens mRNA for carrier family 6, member 8 variant, partial cds PA
BC093009.1 Homo sapiens cathepsin A, mRNA (cDNA clone MGC:110864 IMAGE:30348898), complete cds PA
BC105935.1 Homo sapiens neuralized homolog 2 (Drosophila), mRNA (cDNA clone MGC:125935 IMAGE:40031539), complete cds P
BC107485.1 Homo sapiens neuralized homolog 2 (Drosophila), mRNA (cDNA clone MGC:125934 IMAGE:40031537), complete cds P
BC000597.2 Homo sapiens cathepsin A, mRNA (cDNA clone MGC:1994 IMAGE:3346150), complete cds PA
AK054821.1 Homo sapiens cDNA FLJ30259 fis, clone BRACE2002478, weakly similar to NEURALIZED PROTEIN P
AK307701.1 Homo sapiens cDNA, FLJ97649 P
AK312898.1 Homo sapiens cDNA, FLJ93344, highly similar to Homo sapiens protective protein for beta-galactosidase (galactosialidosis) (PPGB), mRNA P
NM_001127695.1 Homo sapiens cathepsin A (CTSA), transcript variant 2, mRNA PA
AK097786.1 Homo sapiens cDNA FLJ40467 fis, clone TESTI2042326, highly similar to LYSOSOMAL PROTECTIVE PROTEIN PRECURSOR (EC 3.4.16.5) P
AK304536.1 Homo sapiens cDNA FLJ60397 complete cds, highly similar to Lysosomal protective protein precursor (EC 3.4.16.5) P
AF086236.1 Homo sapiens full length insert cDNA clone ZD20E11 A
NM_001167594.1 Homo sapiens cathepsin A (CTSA), transcript variant 3, mRNA PA
NR_074073.1 Homo sapiens neuralized homolog 2 (Drosophila) (NEURL2), non-coding RNA

EST sequences (10 of 1828) [Show all sequences]

AA968851.1 Clone IMAGE:1573807 kidney 3' read A
AA970352.1 Clone IMAGE:1576373 intestine 3' read A
AA971620.1 Clone IMAGE:1584473 lung 3' read A
AA972056.1 Clone IMAGE:1583951 mixed 3' read A
AA972376.1 Clone IMAGE:1584088 mixed 3' read A
AA975913.1 Clone IMAGE:1567986 lung 3' read A
AA976716.1 Clone IMAGE:1585553 lung 3' read A
AA983302.1 Clone IMAGE:1590365 kidney 3' read A
AA987788.1 Clone IMAGE:1588825 kidney 3' read A
AA987828.1 Clone IMAGE:1593928 kidney 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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