> COP9 signalosome subunit 3 (COPS3)
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UGID:131779     UniGene Hs.6076     Homo sapiens (human)   COPS3 Order cDNA clone, Links
COP9 signalosome subunit 3 (COPS3)

Human protein-coding gene COPS3. Represented by 570 ESTs from 228 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 131779 - Hs.6076]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_036121.1 Cops3 gene product M. musculus 100.0 422
NP_001004200.1 Cops3 gene product R. norvegicus 100.0 422
XP_001362211.1 PREDICTED: COP9 signalosome complex subunit 3 M. domestica 100.0 422
XP_001089733.2 PREDICTED: COP9 signalosome complex subunit 3 isoform 3 M. mulatta 100.0 422
XP_003912448.1 PREDICTED: COP9 signalosome complex subunit 3 P. anubis 100.0 422
XP_001160602.1 PREDICTED: COP9 signalosome complex subunit 3 isoform 3 P. troglodytes 100.0 422
NP_003644.2 COPS3 gene product H. sapiens 100.0 422
XP_864801.2 PREDICTED: COP9 signalosome complex subunit 3 isoform 6 C. lupus familiaris 100.0 422
XP_001489831.1 PREDICTED: COP9 signalosome complex subunit 3 E. caballus 100.0 422
XP_002723369.1 PREDICTED: COP9 (constitutive photomorphogenic), subunit 3-like O. cuniculus 99.8 422
XP_001510734.1 PREDICTED: COP9 signalosome complex subunit 3 O. anatinus 99.8 402
XP_002191424.1 PREDICTED: COP9 signalosome complex subunit 3 T. guttata 99.5 422
NP_001006163.1 COPS3 gene product G. gallus 99.5 422
NP_001080121.1 COP9 signalosome complex subunit 3 X. laevis 96.0 422
NP_955979.1 cops3 gene product D. rerio 95.0 422
NP_524190.2 COP9 complex homolog subunit 3 D. melanogaster 60.7 440
NP_568296.1 COP9 signalosome complex subunit 3 A. thaliana 50.0 280
Other hits (2 of 37) [Show all]SpeciesId(%)Len(aa)
NP_001092374.1 COPS3 gene product B. taurus 99.3 422
XP_004012789.1 PREDICTED: COP9 signalosome complex subunit 3 O. aries 99.3 422

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; placenta; mixed; kidney; bladder; umbilical cord; skin; uncharacterized tissue; eye; muscle; vascular; blood; pancreas; embryonic tissue; prostate; lung; heart; intestine; uterus; larynx; lymph; adrenal gland; tonsil; epididymis; spleen; connective tissue; lymph node; ovary; pharynx; liver; mammary gland; cervix; mouth; parathyroid; pituitary gland; bone marrow; ascites; bone; stomach; thyroid; esophagus; thymus
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 17
Map position: 17p11.2
UniSTS entry: Chr 17 D17S1925
UniSTS entry: Chr 17 STS-W80395
UniSTS entry: RH129531
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (9)

NM_003653.3 Homo sapiens COP9 constitutive photomorphogenic homolog subunit 3 (Arabidopsis) (COPS3), transcript variant 1, mRNA PA
AF098109.1 Homo sapiens COP9 complex subunit 3 (COPS3) mRNA, complete cds P
BC001891.1 Homo sapiens COP9 constitutive photomorphogenic homolog subunit 3 (Arabidopsis), mRNA (cDNA clone MGC:1773 IMAGE:3537198), complete cds PA
AK312476.1 Homo sapiens cDNA, FLJ92834, Homo sapiens COP9 constitutive photomorphogenic homolog subunit 3(Arabidopsis) (COPS3), mRNA P
AK297706.1 Homo sapiens cDNA FLJ57332 complete cds, highly similar to COP9 signalosome complex subunit 3 PA
AK302304.1 Homo sapiens cDNA FLJ51147 complete cds, highly similar to COP9 signalosome complex subunit 3 PA
AK316400.1 Homo sapiens cDNA, FLJ79299 complete cds, highly similar to COP9 signalosome complex subunit 3 P
NM_001199125.1 Homo sapiens COP9 constitutive photomorphogenic homolog subunit 3 (Arabidopsis) (COPS3), transcript variant 2, mRNA PA
AF031647.1 Homo sapiens JAB1-containing signalosome subunit 3 (SGN3) mRNA, complete cds P

EST sequences (10 of 570) [Show all sequences]

AA969875.1 Clone IMAGE:1579447 mixed 3' read A
AA994703.1 Clone IMAGE:1625451 mixed 3' read
AA927684.1 Clone IMAGE:1552701 uncharacterized tissue 3' read A
AI026953.1 Clone IMAGE:1643878 testis 3' read A
AI027211.1 Clone IMAGE:1643906 testis 3' read A
AI092817.1 Clone IMAGE:1692364 heart 3' read A
AI143777.1 Clone IMAGE:1708300 heart 3' read P
AI160396.1 Clone IMAGE:1721517 uterus 3' read P
AI167662.1 Clone IMAGE:1682861 parathyroid 3' read A
BX118608.1 Clone IMAGp998O06585_;_IMAGE:267101 skin P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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