> SMAD family member 1 (SMAD1)
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UGID:2073599     UniGene Hs.604588     Homo sapiens (human)   SMAD1 Order cDNA clone, Links
SMAD family member 1 (SMAD1)

Human protein-coding gene SMAD1. Represented by 364 ESTs from 178 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 2073599 - Hs.604588]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001096679.1 PREDICTED: mothers against decapentaplegic homolog 1 M. mulatta 100.0 464
XP_003899284.1 PREDICTED: mothers against decapentaplegic homolog 1 isoform 1 P. anubis 100.0 464
XP_001148403.1 PREDICTED: mothers against decapentaplegic homolog 1 isoform 6 P. troglodytes 100.0 464
NP_001003688.1 SMAD1 gene product H. sapiens 100.0 464
XP_867318.2 PREDICTED: mothers against decapentaplegic homolog 1 isoform 11 C. lupus familiaris 100.0 464
NP_001157354.1 mothers against decapentaplegic homolog 1 E. caballus 100.0 464
NP_999130.1 SMAD1 gene product S. scrofa 100.0 464
NP_001069691.2 SMAD1 gene product B. taurus 100.0 464
XP_004017268.1 PREDICTED: mothers against decapentaplegic homolog 1 O. aries 100.0 464
NP_032565.2 Smad1 gene product M. musculus 99.8 464
XP_001367006.1 PREDICTED: mothers against decapentaplegic homolog 1 M. domestica 99.8 464
XP_001510186.1 PREDICTED: mothers against decapentaplegic homolog 1-like O. anatinus 99.8 464
NP_037262.2 Smad1 gene product R. norvegicus 99.6 467
XP_003221725.1 PREDICTED: mothers against decapentaplegic homolog 1-like A. carolinensis 99.6 464
NP_001079973.1 SMAD family member 1 X. laevis 98.9 463
NP_571431.1 smad1 gene product D. rerio 95.5 471
NP_477017.1 mothers against dpp, isoform A D. melanogaster 89.3 447
NP_498931.2 Protein SMA-2 C. elegans 66.6 406
Other hits (2 of 27) [Show all]SpeciesId(%)Len(aa)
NP_001188384.1 SMAD1 gene product G. gallus 99.3 464
XP_003205468.1 PREDICTED: mothers against decapentaplegic homolog 1-like M. gallopavo 99.3 464

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; uncharacterized tissue; lung; uterus; cervix; heart; ovary; prostate; skin; lymph node; adrenal gland; mouth; liver; pancreas; mixed; stomach; mammary gland; muscle; thymus; embryonic tissue; intestine; vascular; amniotic fluid; umbilical cord; kidney; trachea; thyroid; eye; placenta; pituitary gland; connective tissue; pharynx; adipose tissue; spleen; esophagus; bladder; ganglia; nerve; bone; parathyroid
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 4
Map position: 4q31
UniSTS entry: Chr 4 D4S2549E [Map Viewer]
UniSTS entry: Chr 4 RH102368
UniSTS entry: STS-Z39684
UniSTS entry: Chr 4 ksks229
UniSTS entry: Chr 7 SGC32632 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (12)

BT007386.1 Homo sapiens MAD, mothers against decapentaplegic homolog 1 (Drosophila) mRNA, complete cds P
NM_005900.2 Homo sapiens SMAD family member 1 (SMAD1), transcript variant 1, mRNA P
BC069781.1 Homo sapiens cDNA clone IMAGE:7262583, with apparent retained intron P
BC069804.1 Homo sapiens cDNA clone IMAGE:7262595, with apparent retained intron P
BC069711.1 Homo sapiens cDNA clone IMAGE:7262571, with apparent retained intron P
NM_001003688.1 Homo sapiens SMAD family member 1 (SMAD1), transcript variant 2, mRNA P
BC001878.1 Homo sapiens SMAD family member 1, mRNA (cDNA clone MGC:1376 IMAGE:3546771), complete cds PA
AK293055.1 Homo sapiens cDNA FLJ75507 complete cds, highly similar to Homo sapiens SMAD, mothers against DPP homolog 1 (Drosophila) (SMAD1), transcript variant 2, mRNA P
U59912.1 Human chromosome 4 Mad homolog Smad1 mRNA, complete cds P
U59423.1 Human Smad1 mRNA, complete cds PA
U57456.1 Human transforming growth factor-beta signaling protein-1 (bsp-1) mRNA, complete cds P
U54826.1 Human mad-related protein MADR1 mRNA, complete cds P

EST sequences (10 of 364) [Show all sequences]

AA992928.1 Clone IMAGE:1624243 embryonic tissue 3' read A
AI023010.1 Clone IMAGE:1650950 parathyroid 3' read P
AI022336.1 Clone IMAGE:1654554 mixed 3' read
R19015.1 Clone IMAGE:33515 brain 5' read
AI032160.1 Clone IMAGE:1611301 uncharacterized tissue 3' read
AI090680.1 Clone IMAGE:1692171 heart 3' read P
AI127123.1 Clone IMAGE:1708152 heart 3' read P
AI146485.1 Clone IMAGE:1706820 heart 3' read
BX091882.1 Clone IMAGp998P03133_;_IMAGE:128882 mixed P
AI187115.1 Clone IMAGE:1741662 lung 3' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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