Toll-like receptor 5 (TLR5)

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UGID:2073553 UniGene Hs.604542 Homo sapiens (human) TLR5

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Toll-like receptor 5 (TLR5)

Human protein-coding gene TLR5. Represented by 50 ESTs from 33 cDNA libraries. Corresponds to reference sequence NM_003268.5. [UniGene 2073553 - Hs.604542]

SELECTED PROTEIN SIMILARITIES

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.

Best Hits and Hits from model organisms		Species	Id(%)	Len(aa)
NP_003259.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	TLR5 gene product	H. sapiens	100.0	857
NP_058624.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Tlr5 gene product	M. musculus	74.5	861
NP_001088449.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	toll-like receptor 5	X. laevis	53.4	841
NP_001124067.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	tlr5b gene product	D. rerio	49.6	254
Other hits (2 of 19) [Show all]		Species	Id(%)	Len(aa)
NP_001123934.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	TLR5 gene product	P. troglodytes	99.0	857
NP_001123901.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	TLR5 gene product	M. mulatta	95.9	857

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

	EST Profile:	Approximate expression patterns inferred from EST sources. [Show more entries with profiles like this]
	GEO Profiles:	Experimental gene expression data (Gene Expression Omnibus).
	cDNA Sources:	brain; pancreas; mammary gland; liver; lung; uncharacterized tissue; ovary; mouth; uterus; placenta; testis; trachea; connective tissue; mixed; kidney; skin

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	1
Map position:	1q41-q42
UniSTS entry:	Chr 1	PMC128073P6
UniSTS entry:	Chr 1	TLR5_1375

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (7)

AF051151.1	Homo sapiens Toll/interleukin-1 receptor-like protein 3 (TIL3) mRNA, complete cds	P
BC109118.1	Homo sapiens toll-like receptor 5, mRNA (cDNA clone MGC:126430 IMAGE:40035617), complete cds	P
BC109119.1	Homo sapiens toll-like receptor 5, mRNA (cDNA clone MGC:126431 IMAGE:40035618), complete cds	P
AB060695.1	Homo sapiens TLR5 mRNA for Toll-like receptor 5, complete cds	P
NM_003268.5	Homo sapiens toll-like receptor 5 (TLR5), mRNA	PA
AB445645.1	Homo sapiens TLR5 mRNA for toll-like receptor 5, complete cds	P
U88881.1	Homo sapiens Toll-like receptor 5 (TLR5) mRNA, partial cds	P

EST sequences (10 of 50) [Show all sequences]

BX112000.1	Clone IMAGp998E06612_;_IMAGE:277229	brain		P
BX089684.1	Clone IMAGp998I043970_;_IMAGE:1566795	mixed		A
AI336793.1	Clone IMAGE:1847812	mixed	3' read
AI554481.1	Clone IMAGE:2209526	uterus	3' read	PA
AI628024.1	Clone IMAGE:2279739	uterus	3' read
AI628028.1	Clone IMAGE:2279751	uterus	3' read
AI672306.1	Clone IMAGE:2283769	kidney	3' read	P
CB988553.1	Clone IMAGE:30346374	placenta	5' read	P
BX441259.2	Clone CS0DF016YM17	brain	5' read
BX431083.1	Clone CS0DF016YM17	brain	5' read	P

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria